메뉴 건너뛰기




Volumn , Issue , 2009, Pages 4262-4267

Dynamically dysfunctional protein interactions in the development of Alzheimer's disease

Author keywords

Alzheimer's disease; Differential gene; Dynamics; Dysfunctional pathway; Protein protein interaction; Systems biology

Indexed keywords

ALZHEIMER'S DISEASE; BIO-MOLECULAR; DIFFERENTIAL GENE; DISEASE PROGRESSION; DYNAMICAL PATHWAY; DYSFUNCTIONAL PROTEINS; GENE EXPRESSION DATA; NERVE CELLS; NETWORK-BASED; NETWORK-BASED ANALYSIS; OLD PEOPLE; PROTEIN NETWORK; PROTEIN-PROTEIN INTERACTION SYSTEMS;

EID: 74849132183     PISSN: 1062922X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/ICSMC.2009.5346814     Document Type: Conference Paper
Times cited : (13)

References (37)
  • 1
    • 33750705653 scopus 로고    scopus 로고
    • A century of Alzheimer's disease
    • M.Goedert, M.G. Spillantini, "A century of Alzheimer's disease," Science, vol. 314, pp. 777-781, 2006.
    • (2006) Science , vol.314 , pp. 777-781
    • Goedert, M.1    Spillantini, M.G.2
  • 2
    • 42149184133 scopus 로고    scopus 로고
    • From presenilinase to gamma-secretase, cleave to capacitate
    • W. Xia, " From presenilinase to gamma-secretase, cleave to capacitate," Curr. Alzheimer Res., vol. 5, pp. 172-178, 2008.
    • (2008) Curr. Alzheimer Res , vol.5 , pp. 172-178
    • Xia, W.1
  • 3
    • 33845892752 scopus 로고    scopus 로고
    • Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
    • L. Bertram, M.B. McQueen, K. Mullin, D. Blacker, R.E. Tanzi, " Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database," Nat. Genet., vol. 39, pp. 17-23, 2007.
    • (2007) Nat. Genet , vol.39 , pp. 17-23
    • Bertram, L.1    McQueen, M.B.2    Mullin, K.3    Blacker, D.4    Tanzi, R.E.5
  • 5
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • D.J. Selkoe, "Alzheimer's disease: genes, proteins, and therapy," Physiol. Rev., vol. 81, pp. 741-766, 2001.
    • (2001) Physiol. Rev , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 6
    • 0036736218 scopus 로고    scopus 로고
    • Amyloid precursor protein, presenilins, and alpha-synuclein: Molecular pathogenesis and pharmacological applications in Alzheimer's disease
    • Y.H. Suh, F. Checler, "Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease," Pharmacol. Rev., vol. 54, pp. 469-525, 2002.
    • (2002) Pharmacol. Rev , vol.54 , pp. 469-525
    • Suh, Y.H.1    Checler, F.2
  • 7
    • 1242341923 scopus 로고    scopus 로고
    • Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
    • E.M. Blalock, J.W. Geddes, K.C. Chen, N.M. Porter, W.R. Markesbery, P.W. Landfield, " Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses," Proc. Natl. Acad. Sci. USA, vol. 101, pp. 2173-2178, 2004
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 2173-2178
    • Blalock, E.M.1    Geddes, J.W.2    Chen, K.C.3    Porter, N.M.4    Markesbery, W.R.5    Landfield, P.W.6
  • 8
    • 0742305866 scopus 로고    scopus 로고
    • Network biology: Understanding the cell's functional organization
    • A. Barabasi, Z. Oltvai, " Network biology: understanding the cell's functional organization," Nat. Rev. Genet., vol. 5, pp. 101-113, 2004.
    • (2004) Nat. Rev. Genet , vol.5 , pp. 101-113
    • Barabasi, A.1    Oltvai, Z.2
  • 9
    • 35348891430 scopus 로고    scopus 로고
    • Network-based classification of breast cancer metastasis
    • H.Y. Chuang, E. Lee, Y.T. Liu, D. Lee, T. Ideker, " Network-based classification of breast cancer metastasis," Mol. Syst. Biol., vol. 3, 140, 2007.
    • (2007) Mol. Syst. Biol , vol.3 , pp. 140
    • Chuang, H.Y.1    Lee, E.2    Liu, Y.T.3    Lee, D.4    Ideker, T.5
  • 10
    • 0842309161 scopus 로고    scopus 로고
    • Discovering molecular pathways from protien interaction and gene expression data
    • E. Segal, H. Wang, D. Koller, " Discovering molecular pathways from protien interaction and gene expression data," Bioinformatics, vol. 19(Suppl), pp. i264-i272, 2003.
    • (2003) Bioinformatics , vol.19 , Issue.SUPPL.
    • Segal, E.1    Wang, H.2    Koller, D.3
  • 11
    • 0000801240 scopus 로고    scopus 로고
    • Discovering regulatory and signalling circuits in molecular interaction networks
    • T. Ideker, O. Ozier, B. Schwikowski, A.F. Siegel, " Discovering regulatory and signalling circuits in molecular interaction networks," Bioinformatics, vol. 18(Suppl), pp. S233-S240, 2002.
    • (2002) Bioinformatics , vol.18 , Issue.SUPPL.
    • Ideker, T.1    Ozier, O.2    Schwikowski, B.3    Siegel, A.F.4
  • 12
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • V.G. Tusher, R. Tibshirani, G. Chu, " Significance analysis of microarrays applied to the ionizing radiation response," Proc. Natl. Acad. Sci. USA, vol. 98, pp. 5116-5121, 2001.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 14
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • D.W. Huang, B.T. Sherman, R.A. Lempicki, " Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists," Nucleic Acids Res., vol. 37, pp. 1-13, 2009.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 16
    • 47249120912 scopus 로고    scopus 로고
    • Detecting disease-specific dysregulated pathways via analysis of clinical expression profiles
    • I. Ulitsky, R.M. Karp and R. Shamir, " Detecting disease-specific dysregulated pathways via analysis of clinical expression profiles," Lecture Notes in Comput. Sci., vol. 4955, pp. 347-359, 2008.
    • (2008) Lecture Notes in Comput. Sci , vol.4955 , pp. 347-359
    • Ulitsky, I.1    Karp, R.M.2    Shamir, R.3
  • 17
    • 0035733690 scopus 로고    scopus 로고
    • Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae
    • H. Ge, Z. Liu, G.M. Church, M. Vidal, " Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae," Nat. Genet., vol. 29, pp. 482-486, 2001.
    • (2001) Nat. Genet , vol.29 , pp. 482-486
    • Ge, H.1    Liu, Z.2    Church, G.M.3    Vidal, M.4
  • 18
    • 20744456475 scopus 로고    scopus 로고
    • Correlation between gene expression profiles and protein-protein interactions within and across genomes
    • N. Bhardwaj, H. Lu, " Correlation between gene expression profiles and protein-protein interactions within and across genomes," Bioinformatics, vol. 21, pp. 2730-2738, 2005.
    • (2005) Bioinformatics , vol.21 , pp. 2730-2738
    • Bhardwaj, N.1    Lu, H.2
  • 19
    • 0035445792 scopus 로고    scopus 로고
    • A relationship between gene expression and protein interactions on the proteome scale: Analysis of the bacteriophage T7 and the yeast Saccharomyces cerevisiae
    • A. Grigoriev, "A relationship between gene expression and protein interactions on the proteome scale: analysis of the bacteriophage T7 and the yeast Saccharomyces cerevisiae," Nucleic Acids Res., vol. 29, pp. 3513-3519, 2001.
    • (2001) Nucleic Acids Res , vol.29 , pp. 3513-3519
    • Grigoriev, A.1
  • 25
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID Bioinformatics Resources
    • D.W. Huang, B.T. Sherman, R.A. Lempicki, " Systematic and integrative analysis of large gene lists using DAVID Bioinformatics Resources," Nat. Protoc., vol. 4, pp. 44-57, 2009.
    • (2009) Nat. Protoc , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 26
    • 0002294353 scopus 로고
    • Combining independent tests of significance
    • R.A. Fisher, " Combining independent tests of significance," American Statistician, vol. 2(5), pp. 30, 1948.
    • (1948) American Statistician , vol.2 , Issue.5 , pp. 30
    • Fisher, R.A.1
  • 28
    • 34548583420 scopus 로고    scopus 로고
    • Edge-based scoring and searching method for identifying condition-responsive protein-protein interaction sub-network
    • Z. Guo, Y. Li, X. Gong, C. Yao, W. Ma, D. Wang, Y. Li, J. Zhu, M. Zhang, D. Yang, J. Wang, " Edge-based scoring and searching method for identifying condition-responsive protein-protein interaction sub-network," Bioinformatics, vol. 23, pp. 2121-2128, 2007.
    • (2007) Bioinformatics , vol.23 , pp. 2121-2128
    • Guo, Z.1    Li, Y.2    Gong, X.3    Yao, C.4    Ma, W.5    Wang, D.6    Li, Y.7    Zhu, J.8    Zhang, M.9    Yang, D.10    Wang, J.11
  • 29
    • 2942549112 scopus 로고    scopus 로고
    • Iterative Group Analysis (iGA): A simple tool to enhance sensitivity and facilitate interpretation of microarray experiments
    • Breitling R, Amtmann A, Herzyk P (2004) Iterative Group Analysis (iGA): a simple tool to enhance sensitivity and facilitate interpretation of microarray experiments. BMC Bioinformatics 5:34
    • (2004) BMC Bioinformatics , vol.5 , pp. 34
    • Breitling, R.1    Amtmann, A.2    Herzyk, P.3
  • 31
    • 34748897213 scopus 로고    scopus 로고
    • Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1
    • Q. Liu, C.V. Zerbinatti, J. Zhang, H.S. Hoe, B. Wang, S.L. Cole, J. Herz, L. Muglia, G. Bu, "Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1," Neuron, vol. 56, pp. 66- 78, 2007.
    • (2007) Neuron , vol.56 , pp. 66-78
    • Liu, Q.1    Zerbinatti, C.V.2    Zhang, J.3    Hoe, H.S.4    Wang, B.5    Cole, S.L.6    Herz, J.7    Muglia, L.8    Bu, G.9
  • 32
    • 33747425620 scopus 로고    scopus 로고
    • GSK-3 is essential in the pathogenesis of Alzheimer's disease
    • A. Takashima, " GSK-3 is essential in the pathogenesis of Alzheimer's disease," J. Alzheimers Dis., vol. 9(Suppl), pp. 309-317, 2006.
    • (2006) J. Alzheimers Dis , vol.9 , Issue.SUPPL. , pp. 309-317
    • Takashima, A.1
  • 33
    • 33751218015 scopus 로고    scopus 로고
    • Tau-dependent microtubule disassembly initiated by prefibrillar beta-amyloid
    • M.E. King, H.M. Kan, P.W. Baas, A. Erisir, C.G. Glabe, G.S. Bloom, " Tau-dependent microtubule disassembly initiated by prefibrillar beta-amyloid," J. Cell Biol., vol. 175, pp. 541-546, 2006.
    • (2006) J. Cell Biol , vol.175 , pp. 541-546
    • King, M.E.1    Kan, H.M.2    Baas, P.W.3    Erisir, A.4    Glabe, C.G.5    Bloom, G.S.6
  • 34
    • 0034069495 scopus 로고    scopus 로고
    • Gene Ontology: Tool for the unification of biology
    • The Gene Ontology Consortium
    • The Gene Ontology Consortium (2000) Gene Ontology: tool for the unification of biology. Nature Genet 25:25-29
    • (2000) Nature Genet , vol.25 , pp. 25-29
  • 35
    • 38949175007 scopus 로고    scopus 로고
    • A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging
    • J.A. Miller, M.C. Oldham, D.H. Geschwind, "A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging," J. Neurosci., vol. 28, pp. 1410-1420, 2008.
    • (2008) J. Neurosci , vol.28 , pp. 1410-1420
    • Miller, J.A.1    Oldham, M.C.2    Geschwind, D.H.3
  • 36
    • 55049095941 scopus 로고    scopus 로고
    • Variations in the transcriptome of Alzheimer's disease reveal modular networks involved in cardiovascular diseases
    • M. Ray, J. Ruan and W. Zhang, " Variations in the transcriptome of Alzheimer's disease reveal modular networks involved in cardiovascular diseases," Genome Biol., vol. 9, R148, 2008.
    • (2008) Genome Biol , vol.9
    • Ray, M.1    Ruan, J.2    Zhang, W.3
  • 37
    • 6344229209 scopus 로고    scopus 로고
    • Molecular triangulation: Bridging linkage and molecular-network information for identifying candidate genes in Alzheimer's disease
    • M. Krauthammer, C.A. Kaufmann, T.C. Gilliam, A. Rzhetsky, " Molecular triangulation: bridging linkage and molecular-network information for identifying candidate genes in Alzheimer's disease," Proc. Natl. Acad. Sci. USA, vol. 101, pp. 15148- 15153, 2004.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 15148-15153
    • Krauthammer, M.1    Kaufmann, C.A.2    Gilliam, T.C.3    Rzhetsky, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.