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Volumn 10, Issue 3, 2008, Pages 306-315

Intravenous glial-derived neurotrophic factor gene therapy of experimental Parkinson's disease with Trojan horse liposomes and a tyrosine hydroxylase promoter

Author keywords

Blood brain barrier; Brain gene therapy; Non viral gene transfer; Tyrosine hydroxylase

Indexed keywords

APOMORPHINE; COMPLEMENTARY DNA; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GROWTH HORMONE; LIPOSOME; OXIDOPAMINE; PLASMID DNA; TROJAN HORSE LIPOSOME; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

EID: 40549111959     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1152     Document Type: Article
Times cited : (83)

References (34)
  • 1
    • 0027285510 scopus 로고
    • GDNF: a glial cell line‐derived neurotrophic factor for midbrain dopaminergic neurons
    • 1 Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F. GDNF: a glial cell line‐derived neurotrophic factor for midbrain dopaminergic neurons. Science 1993 ; 260: 1130–1132.
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, LF1    Doherty, DH2    Lile, JD3    Bektesh, S4    Collins, F5
  • 2
    • 0028109526 scopus 로고
    • Glial cell line‐derived neurotrophic factor reverses toxin‐induced injury to midbrain dopaminergic neurons in vivo
    • 2 Hoffer BJ, Hoffman A, Bowenkamp K, et al. Glial cell line‐derived neurotrophic factor reverses toxin‐induced injury to midbrain dopaminergic neurons in vivo. Neurosci Lett 1994 ; 182: 107–111.
    • (1994) Neurosci Lett , vol.182 , pp. 107-111
    • Hoffer, BJ1    Hoffman, A2    Bowenkamp, K3
  • 3
    • 0030950227 scopus 로고    scopus 로고
    • Glial cell line‐derived neurotrophic factor attenuates behavioural deficits and regulates nigrostriatal dopaminergic and peptidergic markers in 6‐hydroxydopamine‐lesioned adult rats: comparison of intraventricular and intranigral delivery
    • 3 Lapchak PA, Miller PJ, Collins F, Jiao S. Glial cell line‐derived neurotrophic factor attenuates behavioural deficits and regulates nigrostriatal dopaminergic and peptidergic markers in 6‐hydroxydopamine‐lesioned adult rats: comparison of intraventricular and intranigral delivery. Neuroscience 1997 ; 78: 61–72.
    • (1997) Neuroscience , vol.78 , pp. 61-72
    • Lapchak, PA1    Miller, PJ2    Collins, F3    Jiao, S4
  • 4
    • 0037451884 scopus 로고    scopus 로고
    • Glial cell line‐derived neurotrophic factor does not enter normal mouse brain
    • 4 Kastin AJ, Akerstrom V, Pan W. Glial cell line‐derived neurotrophic factor does not enter normal mouse brain. Neurosci Lett 2003 ; 340: 239–241.
    • (2003) Neurosci Lett , vol.340 , pp. 239-241
    • Kastin, AJ1    Akerstrom, V2    Pan, W3
  • 5
    • 13144282676 scopus 로고    scopus 로고
    • Intraputamenal infusion of glial cell line‐derived neurotrophic factor in PD: a two‐year outcome study
    • 5 Patel NK, Bunnage M, Plaha P, et al. Intraputamenal infusion of glial cell line‐derived neurotrophic factor in PD: a two‐year outcome study. Ann Neurol 2005 ; 57: 298–302.
    • (2005) Ann Neurol , vol.57 , pp. 298-302
    • Patel, NK1    Bunnage, M2    Plaha, P3
  • 6
    • 0034721690 scopus 로고    scopus 로고
    • Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
    • 6 Kordower JH, Emborg ME, Bloch J, et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 2000 ; 290: 767–773.
    • (2000) Science , vol.290 , pp. 767-773
    • Kordower, JH1    Emborg, ME2    Bloch, J3
  • 7
    • 0036434879 scopus 로고    scopus 로고
    • Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long‐lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer
    • 7 Georgievska B, Kirik D, Bjorklund A. Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long‐lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer. Exp Neurol 2002 ; 177: 461–474.
    • (2002) Exp Neurol , vol.177 , pp. 461-474
    • Georgievska, B1    Kirik, D2    Bjorklund, A3
  • 8
    • 12844287442 scopus 로고    scopus 로고
    • Continuous low‐level glial cell line‐derived neurotrophic factor delivery using recombinant adeno‐associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease
    • 8 Eslamboli A, Georgievska B, Ridley RM, et al. Continuous low‐level glial cell line‐derived neurotrophic factor delivery using recombinant adeno‐associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease. J Neurosci 2005 ; 25: 769–777.
    • (2005) J Neurosci , vol.25 , pp. 769-777
    • Eslamboli, A1    Georgievska, B2    Ridley, RM3
  • 9
    • 29144524873 scopus 로고    scopus 로고
    • Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease
    • 9 Brizard M, Carcenac C, Bemelmans AP, et al. Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease. Neurobiol Dis 2006 ; 21: 90–101.
    • (2006) Neurobiol Dis , vol.21 , pp. 90-101
    • Brizard, M1    Carcenac, C2    Bemelmans, AP3
  • 10
    • 33847195063 scopus 로고    scopus 로고
    • Does neuronal expression of GDNF effectively protect dopaminergic neurons in a rat model of Parkinson's disease?
    • 10 Do Thi NA, Saillour P, Ferrero L, Paunio T, Mallet J. Does neuronal expression of GDNF effectively protect dopaminergic neurons in a rat model of Parkinson's disease? Gene Ther 2007 ; 14: 441–450.
    • (2007) Gene Ther , vol.14 , pp. 441-450
    • Do Thi, NA1    Saillour, P2    Ferrero, L3    Paunio, T4    Mallet, J5
  • 11
    • 1342332987 scopus 로고    scopus 로고
    • Gene targeting in vivo with pegylated immunoliposomes
    • 11 Pardridge WM. Gene targeting in vivo with pegylated immunoliposomes. Methods Enzymol 2003 ; 373: 507–528.
    • (2003) Methods Enzymol , vol.373 , pp. 507-528
    • Pardridge, WM1
  • 12
    • 0034815482 scopus 로고    scopus 로고
    • Receptor‐mediated gene targeting to tissues in the rat in vivo
    • 12 Shi N, Boado RJ, Pardridge WM. Receptor‐mediated gene targeting to tissues in the rat in vivo. Pharm Res 2001 ; 18: 1091–1095.
    • (2001) Pharm Res , vol.18 , pp. 1091-1095
    • Shi, N1    Boado, RJ2    Pardridge, WM3
  • 13
    • 0035940380 scopus 로고    scopus 로고
    • Brain‐specific expression of an exogenous gene after iv. administration
    • 13 Shi N, Zhang Y, Boado RJ, Zhu C, Pardridge WM. Brain‐specific expression of an exogenous gene after iv. administration. Proc Natl Acad Sci USA 2001 ; 98: 12754–12759.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12754-12759
    • Shi, N1    Zhang, Y2    Boado, RJ3    Zhu, C4    Pardridge, WM5
  • 14
    • 0037222013 scopus 로고    scopus 로고
    • Global non‐viral gene transfer to the primate brain following intravenous administration
    • 14 Zhang Y, Schlachetzki F, Pardridge WM. Global non‐viral gene transfer to the primate brain following intravenous administration. Mol Ther 2003 ; 7: 11–18.
    • (2003) Mol Ther , vol.7 , pp. 11-18
    • Zhang, Y1    Schlachetzki, F2    Pardridge, WM3
  • 15
    • 0347555450 scopus 로고    scopus 로고
    • Organ‐specific gene expression in the rhesus monkey eye following intravenous non‐viral gene transfer
    • 15 Zhang Y, Schlachetzki F, Li JY, Boado RJ, Pardridge WM. Organ‐specific gene expression in the rhesus monkey eye following intravenous non‐viral gene transfer. Mol Vis 2003 ; 9: 465–472.
    • (2003) Mol Vis , vol.9 , pp. 465-472
    • Zhang, Y1    Schlachetzki, F2    Li, JY3    Boado, RJ4    Pardridge, WM5
  • 16
    • 13644249272 scopus 로고    scopus 로고
    • Organ‐specific expression of the lacZ gene controlled by the opsin promoter after intravenous gene administration in adult mice
    • 16 Zhu C, Zhang Y, Zhang YF, et al. Organ‐specific expression of the lacZ gene controlled by the opsin promoter after intravenous gene administration in adult mice. J Gene Med 2004 ; 6: 906–912.
    • (2004) J Gene Med , vol.6 , pp. 906-912
    • Zhu, C1    Zhang, Y2    Zhang, YF3
  • 17
    • 0036178992 scopus 로고    scopus 로고
    • Marked dopaminergic cell loss subsequent to developmental, intranigral expression of glial cell line‐derived neurotrophic factor
    • 17 Chun HS, Yoo MS, DeGiorgio LA, et al. Marked dopaminergic cell loss subsequent to developmental, intranigral expression of glial cell line‐derived neurotrophic factor. Exp Neurol 2002 ; 173: 235–244.
    • (2002) Exp Neurol , vol.173 , pp. 235-244
    • Chun, HS1    Yoo, MS2    DeGiorgio, LA3
  • 18
    • 34447571799 scopus 로고    scopus 로고
    • Comparison of cDNA and genomic forms of tyrosine hydroxylase gene therapy of the brain with Trojan horse liposomes
    • 18 Xia CF, Chu C, Li JY, et al. Comparison of cDNA and genomic forms of tyrosine hydroxylase gene therapy of the brain with Trojan horse liposomes. J Gene Med 2007 ; 9: 605–612.
    • (2007) J Gene Med , vol.9 , pp. 605-612
    • Xia, CF1    Chu, C2    Li, JY3
  • 19
    • 34447505329 scopus 로고    scopus 로고
    • Non‐viral gene transfer across the blood‐brain barrier with Trojan horse liposomes, in: Gene Transfer: Delivery and Expression of DNA and RNA
    • 19 Pardridge WM. Non‐viral gene transfer across the blood‐brain barrier with Trojan horse liposomes. In Gene Transfer: Delivery and Expression of DNA and RNA, Friedmann T, Rossi J (eds). Cold Spring Harbor Laboratory Press: Cold Spring Harbor, 2007 ; 701–710.
    • (2007) , pp. 701-710
    • Pardridge, WM1
  • 20
    • 0037249449 scopus 로고    scopus 로고
    • Intravenous nonviral gene therapy causes normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism
    • 20 Zhang Y, Calon F, Zhu C, Boado RJ, Pardridge WM. Intravenous nonviral gene therapy causes normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism. Hum Gene Ther 2003 ; 14: 1–12.
    • (2003) Hum Gene Ther , vol.14 , pp. 1-12
    • Zhang, Y1    Calon, F2    Zhu, C3    Boado, RJ4    Pardridge, WM5
  • 21
    • 0037725257 scopus 로고    scopus 로고
    • A rapid assay for glial cell line‐derived neurotrophic factor and neurturin based on transfection of cells with tyrosine hydroxylase promoter‐luciferase construct
    • 21 Tanaka M, Xiao H, Hirata Y, Kiuchi K. A rapid assay for glial cell line‐derived neurotrophic factor and neurturin based on transfection of cells with tyrosine hydroxylase promoter‐luciferase construct. Brain Res Protoc 2003 ; 11: 119–122.
    • (2003) Brain Res Protoc , vol.11 , pp. 119-122
    • Tanaka, M1    Xiao, H2    Hirata, Y3    Kiuchi, K4
  • 22
    • 1842636306 scopus 로고    scopus 로고
    • Normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism with intravenous nonviral gene therapy and a brain‐specific promoter
    • 22 Zhang Y, Schlachetzki F, Zhang YF, Boado RJ, Pardridge WM. Normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism with intravenous nonviral gene therapy and a brain‐specific promoter. Hum Gene Ther 2004 ; 15: 339–350.
    • (2004) Hum Gene Ther , vol.15 , pp. 339-350
    • Zhang, Y1    Schlachetzki, F2    Zhang, YF3    Boado, RJ4    Pardridge, WM5
  • 23
    • 0025872852 scopus 로고
    • Tissue‐specific and high‐level expression of the human tyrosine hydroxylase gene in transgenic mice
    • 23 Kaneda N, Sasaoka T, Kobayashi K, et al. Tissue‐specific and high‐level expression of the human tyrosine hydroxylase gene in transgenic mice. Neuron 1991 ; 6: 583–594.
    • (1991) Neuron , vol.6 , pp. 583-594
    • Kaneda, N1    Sasaoka, T2    Kobayashi, K3
  • 25
    • 0028172887 scopus 로고
    • 5′ Upstream DNA sequence of the rat tyrosine hydroxylase gene directs high‐level and tissue‐specific expression to catecholaminergic neurons in the central nervous system of transgenic mice
    • 25 Min N, Joh TH, Kim KS, Peng C, Son JH. 5′ Upstream DNA sequence of the rat tyrosine hydroxylase gene directs high‐level and tissue‐specific expression to catecholaminergic neurons in the central nervous system of transgenic mice. Mol Brain Res 1994 ; 27: 281–289.
    • (1994) Mol Brain Res , vol.27 , pp. 281-289
    • Min, N1    Joh, TH2    Kim, KS3    Peng, C4    Son, JH5
  • 26
    • 10744225121 scopus 로고    scopus 로고
    • Cloning and cell type‐specific regulation of the human tyrosine hydroxylase gene promoter
    • 26 Kim TE, Park MJ, Choi EJ, et al. Cloning and cell type‐specific regulation of the human tyrosine hydroxylase gene promoter. Biochem Biophys Res Commun 2003 ; 312: 1123–1131.
    • (2003) Biochem Biophys Res Commun , vol.312 , pp. 1123-1131
    • Kim, TE1    Park, MJ2    Choi, EJ3
  • 27
    • 34547864590 scopus 로고    scopus 로고
    • Nurr1 is phosphorylated by ERK2 in vitro and its phosphorylation upregulates tyrosine hydroxylase expression in SH‐SY5Y cells
    • 27 Zhang T, Jia N, Fei E, et al. Nurr1 is phosphorylated by ERK2 in vitro and its phosphorylation upregulates tyrosine hydroxylase expression in SH‐SY5Y cells. Neurosci Lett 2007 ; 423: 118–122.
    • (2007) Neurosci Lett , vol.423 , pp. 118-122
    • Zhang, T1    Jia, N2    Fei, E3
  • 28
    • 0031784630 scopus 로고    scopus 로고
    • Transcriptional and posttranscriptional control of tyrosine hydroxylase gene expression during persistent stimulation of pituitary adenylate cyclase‐activating polypeptide receptors on PC12 cells: regulation by protein kinase A‐dependent and protein kinase A‐independent pathways
    • 28 Corbitt J, Vivekananda J, Wang SS, Strong R. Transcriptional and posttranscriptional control of tyrosine hydroxylase gene expression during persistent stimulation of pituitary adenylate cyclase‐activating polypeptide receptors on PC12 cells: regulation by protein kinase A‐dependent and protein kinase A‐independent pathways. J Neurochem 1998 ; 71: 478–486.
    • (1998) J Neurochem , vol.71 , pp. 478-486
    • Corbitt, J1    Vivekananda, J2    Wang, SS3    Strong, R4
  • 29
    • 0017656001 scopus 로고
    • Adrenergic, cholinergic, and inactive human neuroblastoma cell lines with the action‐potential Na+ ionophore
    • 29 West GJ, Uki J, Herschman HR, Seeger RC. Adrenergic, cholinergic, and inactive human neuroblastoma cell lines with the action‐potential Na + ionophore. Cancer Res 1977 ; 37: 1372–1376.
    • (1977) Cancer Res , vol.37 , pp. 1372-1376
    • West, GJ1    Uki, J2    Herschman, HR3    Seeger, RC4
  • 30
    • 0030795798 scopus 로고    scopus 로고
    • Intrastriatal injection of an adenoviral vector expressing glial‐cell‐line‐derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease
    • 30 Bilang‐Bleuel A, Revah F, Colin P, et al. Intrastriatal injection of an adenoviral vector expressing glial‐cell‐line‐derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease. Proc Natl Acad Sci USA 1997 ; 94: 8818–8823.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8818-8823
    • Bilang‐Bleuel, A1    Revah, F2    Colin, P3
  • 31
    • 0038014518 scopus 로고    scopus 로고
    • Timecourse of striatal re‐innervation following lesions of dopaminergic SNpc neurons of the rat
    • 31 Stanic D, Finkelstein DI, Bourke DW, Drago J, Horne MK. Timecourse of striatal re‐innervation following lesions of dopaminergic SNpc neurons of the rat. Eur J Neurosci 2003 ; 18: 1175–1188.
    • (2003) Eur J Neurosci , vol.18 , pp. 1175-1188
    • Stanic, D1    Finkelstein, DI2    Bourke, DW3    Drago, J4    Horne, MK5
  • 32
    • 35449007539 scopus 로고    scopus 로고
    • Protection of dopaminergic neurons by electroconvulsive shock in an animal model of Parkinson's disease
    • 32 Anastasia A, de Erausquin GA, Wojnacki J, Masco DH. Protection of dopaminergic neurons by electroconvulsive shock in an animal model of Parkinson's disease. J Neurochem 2007 ; 103: 1542–1552.
    • (2007) J Neurochem , vol.103 , pp. 1542-1552
    • Anastasia, A1    de Erausquin, GA2    Wojnacki, J3    Masco, DH4
  • 33
    • 33745591896 scopus 로고    scopus 로고
    • Decline in exogenous gene expression in primate brain following intravenous administration is due to plasmid degradation
    • 33 Chu C, Zhang Y, Boado RJ, Pardridge WM. Decline in exogenous gene expression in primate brain following intravenous administration is due to plasmid degradation. Pharm Res 2006 ; 23: 1586–1590.
    • (2006) Pharm Res , vol.23 , pp. 1586-1590
    • Chu, C1    Zhang, Y2    Boado, RJ3    Pardridge, WM4
  • 34
    • 33846897981 scopus 로고    scopus 로고
    • Humanization of anti‐human insulin receptor antibody for drug targeting across the human blood‐brain barrier
    • 34 Boado RJ, Zhang YF, Zhang Y, Pardridge WM. Humanization of anti‐human insulin receptor antibody for drug targeting across the human blood‐brain barrier. Biotechnol Bioeng 2007 ; 96: 381–391.
    • (2007) Biotechnol Bioeng , vol.96 , pp. 381-391
    • Boado, RJ1    Zhang, YF2    Zhang, Y3    Pardridge, WM4


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