Coagulation factor Xa cleaves protease-activated receptor-1 and mediates signaling dependent on binding to the endothelial protein C receptor

Journal of Thrombosis and Haemostasis

Volumn 8, Issue 2, 2010, Pages 379-388

  Schuepbach, R A ^a   Riewald, M ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Endothelial cells; Endothelial protein C receptor; Factor Xa; Protease activated receptor 1

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; CONNECTIVE TISSUE GROWTH FACTOR; ENDOTHELIAL PROTEIN C RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLASMIN; PROTEINASE ACTIVATED RECEPTOR 1; THROMBOPLASTIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; CELL PROTECTION; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE CONSTRUCT; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANTIGENS, CD; CELLS, CULTURED; CONNECTIVE TISSUE GROWTH FACTOR; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FACTOR XA; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN C; PROTEIN TRANSPORT; RECEPTOR, PAR-1; RECEPTORS, CELL SURFACE; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; THROMBIN;

EID: 74749096059     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2009.03682.x     Document Type: Article

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