Biosynthesis of bacterial aromatic polyketides

Current Topics in Medicinal Chemistry

Volumn 9, Issue 17, 2009, Pages 1598-1610

  Zhan, Jixun ^a  

^a Utah State University   (United States)

Author keywords

Aromatic polyketides; Biosynthesis; Heterologous hosts; Minimal PKSs; Starter units; Tailoring enzymes

Indexed keywords

12 NORDEFUCOGILVOCARCIN V; 2 OXOISOVALERATE DEHYDROGENASE (LIPOAMIDE); 4' HYDROXYGILVOCARCIN E; 4' HYDROXYGILVOCARCIN M; ACETIC ACID; ACTINORHODINE; ACYL COENZYME A; ANTINEOPLASTIC AGENT; AROMATASE; AROMATIC COMPOUND; BACTERIAL AROMATIC POLYKETIDE; BENASTATIN; DEFUCOGILVOCARCIN V; DIOXYGENASE; ENZYME INHIBITOR; FLUOROACETIC ACID; GILVOCARCIN V; GLYCOSYLTRANSFERASE; HEDAMYCIN; HOMORABELOMYCIN; MALONYL COENZYME A; METHYLTRANSFERASE; MULTIENZYME COMPLEX; OXYGENASE; OXYTETRACYCLINE; POLYKETIDE; POLYKETIDE SYNTHASE; POLYKETIDE SYNTHASE TYPE II; PRADIMICIN A; UNCLASSIFIED DRUG; UNINDEXED DRUG; BIOLOGICAL PRODUCT; MACROLIDE; POLYCYCLIC AROMATIC HYDROCARBON;

ACTINOMADURA; ACTINOMADURA HIBISCA; ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; BACTERIAL GENE; CHEMICAL REACTION; CYCLIZATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; GENE CLUSTER; GENE DELETION; HETEROLOGOUS EXPRESSION; KETOREDUCTION; NONHUMAN; OXIDATION; PROTEIN FUNCTION; REDUCTION; REVIEW; STREPTOMYCES COELICOLOR; STRUCTURE ACTIVITY RELATION; ANIMAL; BIOSYNTHESIS; CATALYSIS; CHEMISTRY; HUMAN; METABOLISM;

ANIMALS; BIOLOGICAL PRODUCTS; CATALYSIS; ESCHERICHIA COLI; HUMANS; MACROLIDES; POLYCYCLIC HYDROCARBONS, AROMATIC; POLYKETIDE SYNTHASES; STREPTOMYCES COELICOLOR;

EID: 74549131570     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802609789941906     Document Type: Review

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