Structural requirements for 2,4- and 3,6-disubstituted pyran biomimetics of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine compounds to interact with monoamine transporters

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 23, 2004, Pages 6301-6315

  Zhang, Shijun ^a   Zhen, Juan ^b,c   Reith, Maarten E A ^b,c   Dutta, Aloke K ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b ILLINOIS STATE UNIVERSITY   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(2 BENZHYDRYLTETRAHYDROPYRAN 4 YL)(4 FLUOROBENZYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(1H IODO 5 YLMETHYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(2 INDOLEMETHYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(3 INDOLEMETHYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(3,4 DICHLOROBENZYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(3,4 DIFLUOROBENZYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(4 AMINOBENZYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(4 BROMOBENZYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(4 CYANOBENZYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(4 FLUOROBENZYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(4 HYDROXYBENZYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(4 IODOBENZYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(4 METHOXYBENZYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)(4 NITROBENZYL)AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)[2 (4 FLUOROPHENYL)ETHYL]AMINE; (6 BENZHYDRYLTETRAHYDROPYRAN 3 YL)BENZYLAMINE; 3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; BENZYLAMINE DERIVATIVE; CITALOPRAM; COCAINE; DOPAMINE; DOPAMINE TRANSPORTER; FUNCTIONAL GROUP; INDOLE DERIVATIVE; NISOXETINE; NORADRENALIN TRANSPORTER; PYRAN DERIVATIVE; SEROTONIN TRANSPORTER; TRITIUM; UNCLASSIFIED DRUG; VANOXERINE;

ANIMAL TISSUE; ARTICLE; ATOM; BINDING AFFINITY; BINDING ASSAY; BINDING COMPETITION; BIOMIMETICS; BRAIN; CIS ISOMER; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; NONHUMAN; PHARMACOPHORE; RAT; STRUCTURE ACTIVITY RELATION; TRANS ISOMER;

ANIMALS; BENZYLAMINES; BINDING, COMPETITIVE; BRAIN CHEMISTRY; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT MODULATORS; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; MOLECULAR MIMICRY; MOLECULAR STRUCTURE; NERVE TISSUE PROTEINS; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PROTEIN BINDING; PYRANS; RATS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS;

EID: 7444243985     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.07.069     Document Type: Article

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