Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs

Journal of Medicinal Chemistry

Volumn 39, Issue 6, 1996, Pages 1201-1209

  Deutsch, Howard M ^a   Shi, Qing ^a   Gruszecka Kowalik, Ewa ^a   Schwer, Margaret M ^b  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b MERCER UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; COCAINE DERIVATIVE; METHYLPHENIDATE;

ALKYLATION; ARTICLE; BINDING SITE; DOPAMINE UPTAKE; DOPAMINERGIC TRANSMISSION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; NONHUMAN; PRESYNAPTIC NERVE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; COCAINE; DOPAMINE; MALE; METHYLPHENIDATE; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029919127     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950697c     Document Type: Article

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