Nociceptin inhibits rat sympathetic preganglionic neurons in situ and in vitro

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 278, Issue 3 47-3, 2000, Pages

  Lai, Chih Chia ^a,b   Wu, Su Ying ^a   Chen, Chiung Tong ^a   Dun, Nae J ^a  

^a East Tennessee State University   (United States)

^b TZU CHI UNIVERSITY   (Taiwan)

Author keywords

Intermediolateral cell column; Opiates; Orphanin FQ

Indexed keywords

NALOXONE; NOCICEPTIN; TETRODOTOXIN;

ANIMAL CELL; ARTICLE; BRADYCARDIA; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; HYPERPOLARIZATION; HYPOTENSION; IMMUNOREACTIVITY; MALE; NERVE STIMULATION; NONHUMAN; PREGANGLIONIC NERVE CELL; PRIORITY JOURNAL; RAT; SYMPATHETIC NERVE CELL; SYMPATHETIC TONE;

EID: 0342514497     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.2000.278.3.r592     Document Type: Article

References (26)

1. Anton, B. J., T. Fein, X. To, L. Li, L. Silberstein, and C. J. Evans. Immunohistochemical localization of ORL-1 in the central nervous system of the rat. J. Comp. Neurol. 368: 229-251, 1996.
2. Bunzow, J. R., C. Saez, M. Mortrud, C. Bouvier, J. T. Williams, M. Low, and D. K. Grandy. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ., δ or κ opioid receptor subtype. FEBS Lett. 347: 284-288, 1994.
3. Champion, H. C., M. A. Czapla, and P. J. Kadowitz. Nociceptin, an endogenous ligand for the ORL1 receptor, decreases cardiac output and total peripheral resistance in the rat. Peptides 18: 729-732,1997.
4. 1 receptor, has novel hypotensive activity in the rat. Life Sci. 60: 241-245, 1997.
5. Chen, Y., Y. Fan, J. Liu, A. Mestek, M. Tian, C. A. Kozak, and L. Yu. Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family. FEBS Lett. 347: 279-283, 1994.
6. Chu, X., N. Xu, P. Li, and J. Q. Wang. Profound inhibition of cardiomotor neurons in the rat rostral ventrolateral medulla by nociceptin (orphanin FQ). Neuroreport 9: 1081-1084, 1998.
7. Dun, N. J., S. L. Dun, and L. L. Hwang. Nociceptin-like immunoreactivity in autonomic nuclei of the rat spinal cord. Neurosci. Lett. 234: 95-98, 1997.
8. Giulian, S., M. Tramontana, A. Lecci, and C. A. Maggi. Effect of nociceptin on heart rate and blood pressure in anaesthetized rats. Eur. J. Pharmacol. 333: 177-179, 1997.
9. 1) receptors possesses systemic vasorelaxant properties. Life Sci. 60: 141-145, 1997.
10. Holaday, J. W. Cardiovascular effects of endogenous opiate systems. Ann. Rev. Pharmacol. Toxicol. 23: 541-594, 1983.
11. Lai, C. C., S. Y. Wu, S. L. Dun, and N. J. Dun. Nociceptin-like immunoreactivity in the rat dorsal horn and inhibition of substantia gelatinosa neurons. Neuroscience 81: 887-891, 1997.
12. Lai, C. C., S. Y. Wu, H. H. Lin, and N. J. Dun. Excitatory action of pituitary adenylate cyclase activating polypeptide on rat sympathetic preganglionic neurons in vivo and in vitro. Brain Res. 748: 189-194, 1997.
13. Laubie, M., H. Schmitt, J. Canellas, J. Roquebert, and P. Desmichel. Centrally mediated bradycardia and hypotension induced by narcotic analgesics: dextromoramide and fentanyl. Eur. J. Pharmacol. 28: 66-75, 1974.
14. Liebel, J. T., D. Swandulla, and H. U. Zeilhofer. Modulation of excitatory synaptic transmission by nociceptin in superficial dorsal horn neurones of the neonatal rat spinal cord. Br. J. Pharmacol. 121: 425-432, 1997.
15. Meunier, J.-C., C. Mollereau, L. Toll, C. Suaudeau, C. Moisand, P. Alvinerie, J.-C. Butour, J.-C. Guillemot, P. Ferrera, B. Monserrat, H. Mazarguil, G. Vassart, M. Parmentier, and J. Constintin. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 377: 532-535, 1995.
16. Mollereau, C., M. Parmentier, P. Mailleux, J.-L. Butour, C. Moisand, P. Chalon, D. Caput, G. Vassart, and J.-C. Meunier. ORL1, a novel member of the opioid receptor family. FEBS Lett. 341: 33-38, 1994.
17. Neal, C. R., Jr., A. Mansour, R. Reinscheid, H. P. Nothacker, O. Civelli, and S. J. Watson, Jr. Localization of orphanin FQ (nociceptin) peptide and messenger RNA in the central nervous system of the rat. J. Comp. Neurol. 406: 503-547, 1999.
18. Paakkar, P., and G. Feuerstein. Opioid peptides in cardiovascular and respiratory regulation. In: The Pharmacology of Opioid Peptides, edited by L. F. Tseng. Amsterdam, The Netherlands: Harwood Academic, 1995, p. 425-444.
19. Reinscheid, R. K., H.-P. Nothacker, A. Bourson, A. Ardati, R. A. Henningson, J. R. Bunzow, D. K. Grandy, H. Langen, F. J. Monsma, Jr., and O. Civelli. Orphanin FQ: a neuropeptide that activates an opioid-like G protein-coupled receptor. Science 270: 792-794, 1995.
20. Sapru, H. N., R. N. Willette, and A. J. Krieger. Stimulation of pulmonary J receptors by an enkephalin-analog. J. Pharmacol. Exp. Ther. 217: 228-234, 1981.
21. Shen, E., and N. J. Dun. Neonate rat sympathetic preganglionic neurons intracellularly labelled with lucifer yellow in thin spinal cord slices. J. Auton. Nerv. Syst. 29: 247-254, 1990.
22. Shen, E., N. Mo, and N. J. Dun. APV-sensitive dorsal root afferent transmission to neonate rat sympathetic preganglionic neurons in vitro. J. Neurophysiol. 64: 991-999, 1990.
23. Shen, E., S. Y. Wu, and N. J. Dun. Spontaneous and transmitter-induced rhythmic activity in neonatal rat sympathetic preganglionic neurons in vitro. J. Neurophysiol. 71: 1197-1205, 1994.
24. Wick, M. J., S. R. Minnerath, X. Lin, R. Elde, P. Y. Law, and H. H. Loh. Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned μ, δ and κ opioid receptors. Mo. Brain Res. 117: 1609-1611, 1994.
25. Willette, R. N., P. Gatti, S. B. Gertner, and H. N. Sapru. Pulmonary vagal afferent stimulants in the conscious rat: opioids and phenyldiguanide. Pharmacol. Biochem. Behav. 17: 19-23, 1982.
26. Wu, S. Y., and N. J. Dun. Excitatory amino acids depress synaptic currents in neonate rat sympathetic preganglionic neurons. J. Neurophysiol. 69: 2030-2038, 1993.