Electrically evoked [3H]GABA release from cerebral cortical cultures: An in vitro approach for studying glutamate-induced neurotoxicity

Synapse

Volumn 30, Issue 3, 1998, Pages 247-254

  Tomasini, Maria Cristina ^a   Antonelli, Tiziana ^a  

^a UNIVERSITY OF FERRARA   (Italy)

Author keywords

Cerebral cortical cells; Electrical field stimulation; Excitotoxicity; Glutamate

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMIC ACID; TRITIUM; NEUROTOXIN;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; ELECTROSTIMULATION; NERVE CELL LESION; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; ANALYSIS OF VARIANCE; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT; KINETICS; METABOLISM; NERVE CELL; NEWBORN; SPRAGUE DAWLEY RAT; TRANSPORT AT THE CELLULAR LEVEL;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL TRANSPORT; CELLS, CULTURED; CEREBRAL CORTEX; ELECTRIC STIMULATION; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; KINETICS; NEURONS; NEUROTOXINS; RATS; RATS, SPRAGUE-DAWLEY; TRITIUM;

EID: 0031595253     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(199811)30:3<247::AID-SYN2>3.0.CO;2-B     Document Type: Article

References (50)

1. Abdulla, E.M., and Campbell, I.C. (1993) In vitro tests of neurotoxicity. J. Pharmacol. Toxicol. Methods, 29:69-75.
2. Alho, H., Ferrarese, C., Vicini, S., and Vaccarino, F. (1988) Subsets of GABAergic neurons in dissociated cell cultures of neonatal rat cerebral cortex show co-localization with specific modulator peptides. Dev. Brain Res., 39:193-204.
3. Andinè, P., Sandberg, M., Bågenholm, R., Lehmann, A., and Hagberg, H. (1991) Intra- and extracellular changes of amino acids in the cerebral cortex of the neonatal rat during hypoxic-ischemia. Dev. Brain Res., 64:115-120.
4. Ankarcrona, M., Dypbukt, J.M., Bonfoco, E., Zhivotovsky, B., Orrenius, S., Lipton, S.A., and Nicotera, P. (1995) Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function. Neuron, 15:961-973.
5. Badini, I., Zerbetto, E., Bianchi, C., Beani, L., and Siniscalchi, A. (1996) Post-hypoxic recovery of acetylcholine release: Different sensitivity of guinea pig neocortical and striatal slices. Neurochem. Int., 29:477-485.
6. Beani, L., Bianchi, C., Siniscalchi, A., Tanganelli, S., and Veratti, E. (1984) Different approaches to study acetylcholine release: Endogenous Ach versus tritium efflux. Naunyn Schmiedebergs Arch. Pharmacol., 328:119-126.
7. Benveniste, H., Drejer, J., Schousboe, A., and Diemer, N.H. (1984) Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem., 43:1369-1374.
8. Bianchi, C., Beani, L., Antonelli, T., Vedovato, M., Calò, G., and Tomasini, C. (1992) A simple method for electrical field stimulation of cultured granule cells. J. Neurosci. Methods, 45:175-182.
9. Buisson, A., and Choi, D.W. (1995) The inhibitory mGluR agonist, s-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death. Neuropharmacology, 34:1081-1087.
10. Cai, N., and Erdö, S.L. (1992) Developmental dissociation of pharmacological and neurotoxic effects of excitatory amino acids. Dev. Brain Res., 66:262-265.
11. Choi, D.W. (1990a) Methods for antagonizing glutamate neurotoxicity. Cerebrovasc. Brain Metab. Rev., 2:105-147.
12. Choi, D.W. (1990b) Cerebral hypoxia: Some new approaches and unanswered questions. J. Neurosci., 10:2493-2501.
13. Choi, D.W. (1995) Calcium: Still center-stage in hypoxic-ischemic neuronal death. Trends Neurosci., 18:58-60.
14. Choi, D.W., Koh, J.Y., and Peters, S. (1988) Pharmacology of glutamate neurotoxicity in cortical cell culture: Attenuation by NMDA antagonists. J. Neurosci., 8:185-196.
15. Clifford, D.B., Zorumski, C.F., and Olney, J.W. (1989) Ketamine and MK801 prevent degeneration of thalamic neurons induced by focal cortical seizures. Exp. Neurol., 105:272-279.
16. Danysz, W., Parsons, C.G., Bresink, I., and Quack, G. (1995) A revived target for drug development? Glutamate in CNS disorders. DN&P, 8:261-277.
17. Dessi, F., Charriaut-Marlangue, C., and Ben-Ari, Y. (1994) Glutamate-induced neuronal death in cerebellar culture is mediated by two distinct components: A sodium-chloride component and a calcium component. Brain Res., 650:49-55.
18. 3H-GABA from cultured mouse cerebral cortex interneurons. J. Neurosci., 7:2910-2916.
19. Durkin, J.P., Tremblay, R., Buchan, A., Blosser, J., Chakravarthy, B., Mealing, G., Morley, P., and Song, D. (1996) An early loss in membrane protein kinase C activity precedes the excitatory amino acid-induced death of primary cortical neurons. J. Neurochem., 66:951-962.
20. Faden, A.I., Demediuk, P., Scott Panter, S., and Vink, R. (1989) The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science, 244:798-800.
21. Frandsen, A., and Schousboe, A. (1987) Time and concentration dependency of the toxicity of excitatory amino acids on cerebral neurons in primary culture. Neurochem. Int., 10:583-591.
22. Frandsen, A., Andersen, C.F., and Schousboe, A. (1992) Possible role of cGMP in excitatory amino acid induced cytotoxicity in cultured cerebral cortical neurons. Neurochem. Res., 17:35-43.
23. Garthwaite, G., Williams, G.D., and Garthwaite, J. (1992) Glutamate toxicity: An experimental and theoretical analysis. Eur. J. Neurosci., 4:353-360.
24. Globus, M.Y.T., Busto, R., Dietrich, W.D., Martinez, E., Valdes, I. and Ginsberg, M.D. (1988) Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and γ-aminobutyric acid studied by intracerebral microdialysis. J. Neurochem., 51:1455-4164.
25. Goldberg, M.P., Weiss, J.H., Pham, P.C., and Choi, D. (1987) N-methyl-D-aspartate receptors mediate bypoxic neuronal injur in cortical culture. J. Pharmacol. Exp. Ther., 243:784-791.
26. Griffiths, T., Evans, M.C., and Meldrum, B.S. (1984) Status epilepticus: The reversibility of calcium loading and acute neuronal pathological changes in the rat hippocampus. Neuroscience, 12:557-567.
27. 2+-accumulation in cortical cell culture correlates with subsequent neuronal degeneration. J. Neurosci., 13:1993-2000.
28. 2+ concentration in isolated nerve terminals following metabolic inhibition: Possible relevance to hypoglycemia and anoxia. Neuroscience, 27:175-182.
29. Koh, J.Y., and Choi, D. (1991) Selective blockade of non-NMDA receptors does not block rapidly triggered glutamate-induced neuronal death. Brain Res., 548:318-321.
30. Larsson, O.M., Drejer, J., Hertz, L., and Schousboe, A. (1983) Ion dependency of uptake and release of GABA and (RS)-nipecotic acid studied in cultured mouse brain cortex neurons. J. Neurosci. Res., 9:291-302.
31. Lloyd, H.G.E., Morrison, M., and Johnston, A.R. (1992) Excitatory amino acid and purine release from hippocampal synaptosomes: An in vitro model for studying presynaptic mechanisms involved in ischaemia. Mol. Neuropharmacol., 2:211-214.
32. Lustig, H.S., von Brauchitsch, K.L., Chan, J., and Greenberg, D.A. (1992) Cyclic GMP modulators and excitotoxic injury in cerebral cortical cultures. Brain Res., 577:343-346.
33. Martin, R.L., Lloyd, H.G.E., and Cowan, A. (1994) The early events of oxygen and glucose deprivation: Setting the scene for neuronal death? Trends Neurosci., 17:251-257.
34. Meldhal, A.S., and Fonnum, F. (1995) The effects of a purified toxic extract of Prymnesium patelliferum on transport of ions through the plasma membrane of synaptosomes. Toxicon, 33:1071-1086.
35. Milusheva, E., Doda, M., Pasztor, E., Lajtha. A., Sershen, H., and Vizi, E.S. (1992) Regulatory interactions among axon terminals affecting the release of different transmitters from rat striatal slices under hypoxic and hypoglycemic conditions. J. Neurochem., 59:946-952.
36. Mori, H., and Mishina, M. (1995) Review: Neurotransmitter receptors. VIII. Structure and function of the NMDA receptor channel. Neuropharmacology, 34:1219-1237.
37. Mosmann, T. (1983) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods, 65:55-63.
38. Pulsinelli, W. (1992) Pathophysiology of acute ischaemic stroke. Lancet, 339:533-536.
39. Randall, R.D., and Thayer, S.A. (1992) Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J. Neurosci., 12:1882-1895.
40. Regan, R.F., Panter, S.S., Witz, A., Tilly, J.L., and Giffard, R.G. (1995) Ultrastructure of excitotoxic neuronal death in murine cortical culture. Brain Res., 705:188-198.
41. Schousboe, A. (1982) Metabolism and function of neurotransmitter. In: Neuroscience Approached Through Cell-Culture. Pfeiffer, S.E., ed. CRC Press, Boca Raton, FL, pp. 107-141.
42. Schousboe, A., Drejer, J., Hansen, G.H., and Meier, E. (1985) Cultured neurons as model systems for biochemical and pharmacological studies on receptors for neurotransmitter amino acids. Dev. Neurosci., 7:252-262.
43. Siesjö, B.K., Memezawa, H., and Smith, M.L. (1991) Neurotoxicity: Pharmacological implications. Fundam. Clin. Pharmacol., 5:755-767.
44. Snodgrass, S.R., White, W.F., Biales, B., and Dichter, M. (1980) Biochemical correlates of GABA function in rat cortical neurons in culture. Brain Res., 190:123-138.
45. Sweeney, M.I., Yager, J.Y., Walz, W., and Juurlink, H.J. (1995) Cellular mechanisms involved in brain ischemia. Can. J. Physiol. Pharmacol., 73:1525-1535.
46. Tamura, Y., Sato, Y., Yokota, T., Akaike, A., Sasa, M., and Takaori, S. (1993) Ifenprodil prevents glutamate cytotoxicity via polyamine modulatory sites of N-methyl-D-aspartate receptors in cultured cortical neurons. J. Pharmacol. Exp. Ther., 265:1017-1025.
47. G-nitro-L-arginine of L-glutamate-induced neurotoxicity in cultured neonatal rat cortical neurons. Prolonged application enhances neuroprotective efficacy. Neuroscience, 55:893-901.
48. Watkins, J.C., Krogsgaard-Larsen, P., and Honorè, T. (1990) Structure-activity relationship in the development of excitatory amino acid receptor agonists and competitive antagonists. Trends Pharmacol. Sci., 11:25-33.
49. ++ concentration and subsequent loss of neuronal function in individual neocortical neurons in culture. Proc. Natl. Acad. Sci. USA, 91:12303-12307.
50. Wong, E., Kemp, J.A., Priestley, T., Knight, A.R., Woodruff, G.N., and Iversen, L.L. (1986) The anticonvulsivant MK801 is a potent N-methyl-D-aspartate antagonist. Proc. Natl. Acad. Sci. USA, 83: 7104-7108.