Novel semisynthetic spin-labeled derivatives of podophyllotoxin with cytotoxic and antioxidative activity

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 3, 2010, Pages 983-986

  Zhang, Jia Qiang ^a   Zhang, Zhi Wei ^a   Hui, Ling ^c   Chen, Shi Wu ^a,b   Tian, Xuan ^a  

^a LANZHOU UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

^c LANZHOU GENERAL HOSPITAL   (China)

Author keywords

Antioxidants; Antitumor; Nitroxides; Podophyllotoxin

Indexed keywords

ETOPOSIDE; PODOPHYLLOTOXIN DERIVATIVE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CYTOTOXIN; PODOPHYLLOTOXIN; SPIN LABELING;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL STRAIN A 549; CELL STRAIN HL 60; CELL STRAIN RPMI 8226; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SOLUBILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; PARTITION COEFFICIENT; TUMOR CELL LINE; ANIMAL; COMPARATIVE STUDY; HT 29 CELL LINE; RAT; SPIN LABELING; SPRAGUE DAWLEY RAT; SYNTHESIS;

RATTUS;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CELL LINE, TUMOR; CYTOTOXINS; HT29 CELLS; HUMANS; PODOPHYLLOTOXIN; RATS; RATS, SPRAGUE-DAWLEY; SPIN LABELS;

EID: 74349103565     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.048     Document Type: Article

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