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Volumn 79, Issue 6, 2010, Pages 842-852

Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1

Author keywords

Anti invasion; Anti proliferation; Nasopharyngeal carcinoma (NPC); Reverse phase protein array; YC 1 mechanisms

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; ACETYL COENZYME A CARBOXYLASE; BETA CATENIN; CAVEOLIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

EID: 74249106458     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.10.021     Document Type: Article
Times cited : (19)

References (48)
  • 3
    • 33846529846 scopus 로고    scopus 로고
    • Cancer of the pancreas
    • Schottenfeld D., and Fraumeni Jr. J.F. (Eds), Oxford University Press, New York
    • Anderson K.E., Mack T.M., and Silverman D.T. Cancer of the pancreas. In: Schottenfeld D., and Fraumeni Jr. J.F. (Eds). Cancer epidemiology and prevention (2006), Oxford University Press, New York 721-762
    • (2006) Cancer epidemiology and prevention , pp. 721-762
    • Anderson, K.E.1    Mack, T.M.2    Silverman, D.T.3
  • 5
    • 13144275282 scopus 로고    scopus 로고
    • Advanced nasopharyngeal carcinoma treated with chemotherapy and radiotherapy: distant metastasis and local recurrence
    • Isobe K., Ito H., Shigematsu N., Kawada T., Yasuda S., Hara R., et al. Advanced nasopharyngeal carcinoma treated with chemotherapy and radiotherapy: distant metastasis and local recurrence. Int J Oncol 12 (1998) 1183-1187
    • (1998) Int J Oncol , vol.12 , pp. 1183-1187
    • Isobe, K.1    Ito, H.2    Shigematsu, N.3    Kawada, T.4    Yasuda, S.5    Hara, R.6
  • 6
    • 0028109332 scopus 로고
    • YC-1, a novel activator of platelet guanylate cyclase
    • Ko F.N., Wu C.C., Kuo S.C., Lee F.Y., and Teng C.M. YC-1, a novel activator of platelet guanylate cyclase. Blood 84 (1994) 4226-4233
    • (1994) Blood , vol.84 , pp. 4226-4233
    • Ko, F.N.1    Wu, C.C.2    Kuo, S.C.3    Lee, F.Y.4    Teng, C.M.5
  • 7
    • 34547660100 scopus 로고    scopus 로고
    • Preclinical evaluation of YC-1, a HIF inhibitor, for the prevention of tumor spreading
    • Shin D.H., Kim J.H., Jung Y.J., Kim K.E., Jeong J.M., Chun Y.S., et al. Preclinical evaluation of YC-1, a HIF inhibitor, for the prevention of tumor spreading. Cancer Lett 255 (2007) 107-116
    • (2007) Cancer Lett , vol.255 , pp. 107-116
    • Shin, D.H.1    Kim, J.H.2    Jung, Y.J.3    Kim, K.E.4    Jeong, J.M.5    Chun, Y.S.6
  • 8
    • 23044433522 scopus 로고    scopus 로고
    • YC-1 [3-(5′-hydroxymethyl-2γ-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models
    • Pan S.L., Guh J.H., Peng C.Y., Wang S.W., Chang Y.L., Cheng F.C., et al. YC-1 [3-(5′-hydroxymethyl-2γ-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models. J Pharmacol Exp Ther 314 (2005) 35-42
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 35-42
    • Pan, S.L.1    Guh, J.H.2    Peng, C.Y.3    Wang, S.W.4    Chang, Y.L.5    Cheng, F.C.6
  • 9
    • 1842525176 scopus 로고    scopus 로고
    • Versatile pharmacological actions of YC-1: anti-platelet to anticancer
    • Chun Y.S., Yeo E.J., and Park J.W. Versatile pharmacological actions of YC-1: anti-platelet to anticancer. Cancer Lett 207 (2004) 1-7
    • (2004) Cancer Lett , vol.207 , pp. 1-7
    • Chun, Y.S.1    Yeo, E.J.2    Park, J.W.3
  • 10
    • 34948817308 scopus 로고    scopus 로고
    • Proteomic approach to studying the cytotoxicity of YC-1 on U937 leukemia cells and antileukemia activity in orthotopic model of leukemia mice
    • Chung J.G., Yang J.S., Huang L.J., Lee F.Y., Teng C.M., Tsai S.C., et al. Proteomic approach to studying the cytotoxicity of YC-1 on U937 leukemia cells and antileukemia activity in orthotopic model of leukemia mice. Proteomics 7 (2007) 3305-3317
    • (2007) Proteomics , vol.7 , pp. 3305-3317
    • Chung, J.G.1    Yang, J.S.2    Huang, L.J.3    Lee, F.Y.4    Teng, C.M.5    Tsai, S.C.6
  • 11
    • 27644518437 scopus 로고    scopus 로고
    • YC-1 suppresses constitutive nuclear factor-kappaB activation and induces apoptosis in human prostate cancer cells
    • Huang Y.T., Pan S.L., Guh J.H., Chang Y.L., Lee F.Y., Kuo S.C., et al. YC-1 suppresses constitutive nuclear factor-kappaB activation and induces apoptosis in human prostate cancer cells. Mol Cancer Ther 4 (2005) 1628-1635
    • (2005) Mol Cancer Ther , vol.4 , pp. 1628-1635
    • Huang, Y.T.1    Pan, S.L.2    Guh, J.H.3    Chang, Y.L.4    Lee, F.Y.5    Kuo, S.C.6
  • 12
    • 0037414180 scopus 로고    scopus 로고
    • YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1
    • Yeo E.J., Chun Y.S., Cho Y.S., Kim J., Lee J.C., Kim M.S., et al. YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1. J Natl Cancer Inst 95 (2003) 516-525
    • (2003) J Natl Cancer Inst , vol.95 , pp. 516-525
    • Yeo, E.J.1    Chun, Y.S.2    Cho, Y.S.3    Kim, J.4    Lee, J.C.5    Kim, M.S.6
  • 13
    • 42549131961 scopus 로고    scopus 로고
    • Inhibition of Stat3 activity by YC-1 enhances chemo-sensitivity in hepatocellular carcinoma
    • Lau C.K., Yang Z.F., Lam S.P., Lam C.T., Ngai P., Tam K.H., et al. Inhibition of Stat3 activity by YC-1 enhances chemo-sensitivity in hepatocellular carcinoma. Cancer Biol Ther 6 (2007) 1900-1907
    • (2007) Cancer Biol Ther , vol.6 , pp. 1900-1907
    • Lau, C.K.1    Yang, Z.F.2    Lam, S.P.3    Lam, C.T.4    Ngai, P.5    Tam, K.H.6
  • 15
    • 53849131648 scopus 로고    scopus 로고
    • YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway
    • Wu S.Y., Pan S.L., Chen T.H., Liao C.H., Huang D.Y., Guh J.H., et al. YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway. Br J Pharmacol 155 (2008) 505-513
    • (2008) Br J Pharmacol , vol.155 , pp. 505-513
    • Wu, S.Y.1    Pan, S.L.2    Chen, T.H.3    Liao, C.H.4    Huang, D.Y.5    Guh, J.H.6
  • 16
    • 33745728147 scopus 로고    scopus 로고
    • YC-1 induces S cell cycle arrest and apoptosis by activating checkpoint kinases
    • Yeo E.J., Ryu J.H., Chun Y.S., Cho Y.S., Jang I.J., Cho H., et al. YC-1 induces S cell cycle arrest and apoptosis by activating checkpoint kinases. Cancer Res 66 (2006) 6345-6352
    • (2006) Cancer Res , vol.66 , pp. 6345-6352
    • Yeo, E.J.1    Ryu, J.H.2    Chun, Y.S.3    Cho, Y.S.4    Jang, I.J.5    Cho, H.6
  • 17
    • 33750456480 scopus 로고    scopus 로고
    • Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells
    • Tibes R., Qiu Y., Lu Y., Hennessy B., Andreeff M., Mills G.B., et al. Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells. Mol Cancer Ther 5 (2006) 2512-2521
    • (2006) Mol Cancer Ther , vol.5 , pp. 2512-2521
    • Tibes, R.1    Qiu, Y.2    Lu, Y.3    Hennessy, B.4    Andreeff, M.5    Mills, G.B.6
  • 18
    • 17844377553 scopus 로고    scopus 로고
    • Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma
    • Sheehan K.M., Calvert V.S., Kay E.W., Lu Y., Fishman D., Espina V., et al. Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma. Mol Cell Proteomics 4 (2005) 346-355
    • (2005) Mol Cell Proteomics , vol.4 , pp. 346-355
    • Sheehan, K.M.1    Calvert, V.S.2    Kay, E.W.3    Lu, Y.4    Fishman, D.5    Espina, V.6
  • 19
    • 49749088333 scopus 로고    scopus 로고
    • Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: accurate detection of CA19-9 levels in pancreatic cancer
    • Grote T., Siwak D.R., Fritsche H.A., Joy C., Mills G.B., Simeone D., et al. Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: accurate detection of CA19-9 levels in pancreatic cancer. Proteomics 8 (2008) 3051-3060
    • (2008) Proteomics , vol.8 , pp. 3051-3060
    • Grote, T.1    Siwak, D.R.2    Fritsche, H.A.3    Joy, C.4    Mills, G.B.5    Simeone, D.6
  • 21
    • 62349092784 scopus 로고    scopus 로고
    • A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy
    • Kim W.Y., Chang D.J., Hennessy B., Kang H.J., Yoo J., Han S.H., et al. A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy. Cancer Prev Res (Phila PA) 1 (2008) 577-587
    • (2008) Cancer Prev Res (Phila PA) , vol.1 , pp. 577-587
    • Kim, W.Y.1    Chang, D.J.2    Hennessy, B.3    Kang, H.J.4    Yoo, J.5    Han, S.H.6
  • 22
    • 34248193845 scopus 로고    scopus 로고
    • Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer
    • Zhang Q., Bhola N.E., Lui V.W., Siwak D.R., Thomas S.M., Gubish C.T., et al. Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer. Mol Cancer Ther 6 (2007) 1414-1424
    • (2007) Mol Cancer Ther , vol.6 , pp. 1414-1424
    • Zhang, Q.1    Bhola, N.E.2    Lui, V.W.3    Siwak, D.R.4    Thomas, S.M.5    Gubish, C.T.6
  • 23
    • 70349256524 scopus 로고    scopus 로고
    • STAT3 activation contributes directly to Epstein-Barr virus-mediated invasiveness of nasopharyngeal cancer cells in vitro
    • Lui V.W., Wong E.Y., Ho Y., Hong B., Wong S.C., Tao Q., et al. STAT3 activation contributes directly to Epstein-Barr virus-mediated invasiveness of nasopharyngeal cancer cells in vitro. Int J Cancer 125 (2009) 1884-1893
    • (2009) Int J Cancer , vol.125 , pp. 1884-1893
    • Lui, V.W.1    Wong, E.Y.2    Ho, Y.3    Hong, B.4    Wong, S.C.5    Tao, Q.6
  • 24
    • 34247480458 scopus 로고    scopus 로고
    • Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1
    • Lui V.W., Boehm A.L., Koppikar P., Leeman R.J., Johnson D., Ogagan M., et al. Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1. Mol Pharmacol 71 (2007) 1435-1443
    • (2007) Mol Pharmacol , vol.71 , pp. 1435-1443
    • Lui, V.W.1    Boehm, A.L.2    Koppikar, P.3    Leeman, R.J.4    Johnson, D.5    Ogagan, M.6
  • 25
    • 72149129447 scopus 로고    scopus 로고
    • A small molecule inhibitor of NF-kappaB, dehydroxymethylepoxyquinomicin (DHMEQ), suppresses growth and invasion of nasopharyngeal carcinoma (NPC) cells
    • in press
    • Wong JH, Lui VW, Umezawa K, Ho Y, Wong EY, Ng MH, et al. A small molecule inhibitor of NF-kappaB, dehydroxymethylepoxyquinomicin (DHMEQ), suppresses growth and invasion of nasopharyngeal carcinoma (NPC) cells. Cancer Lett; in press.
    • Cancer Lett
    • Wong, J.H.1    Lui, V.W.2    Umezawa, K.3    Ho, Y.4    Wong, E.Y.5    Ng, M.H.6
  • 26
    • 0142025133 scopus 로고    scopus 로고
    • Mitogenic effects of gastrin-releasing peptide in head and neck squamous cancer cells are mediated by activation of the epidermal growth factor receptor
    • Lui V.W., Thomas S.M., Zhang Q., Wentzel A.L., Siegfried J.M., Li J.Y., et al. Mitogenic effects of gastrin-releasing peptide in head and neck squamous cancer cells are mediated by activation of the epidermal growth factor receptor. Oncogene 22 (2003) 6183-6193
    • (2003) Oncogene , vol.22 , pp. 6183-6193
    • Lui, V.W.1    Thomas, S.M.2    Zhang, Q.3    Wentzel, A.L.4    Siegfried, J.M.5    Li, J.Y.6
  • 27
    • 0024332127 scopus 로고
    • Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas
    • Glaser R., Zhang H.Y., Yao K.T., Zhu H.C., Wang F.X., Li G.Y., et al. Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas. Proc Natl Acad Sci USA 86 (1989) 9524-9528
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9524-9528
    • Glaser, R.1    Zhang, H.Y.2    Yao, K.T.3    Zhu, H.C.4    Wang, F.X.5    Li, G.Y.6
  • 28
    • 0020546128 scopus 로고
    • Cytogenetic studies on an epithelial cell line derived from poorly differentiated nasopharyngeal carcinoma
    • Sizhong Z., Xiukung G., and Yi Z. Cytogenetic studies on an epithelial cell line derived from poorly differentiated nasopharyngeal carcinoma. Int J Cancer 31 (1983) 587-590
    • (1983) Int J Cancer , vol.31 , pp. 587-590
    • Sizhong, Z.1    Xiukung, G.2    Yi, Z.3
  • 29
    • 3943107573 scopus 로고    scopus 로고
    • Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
    • Sancar A., Lindsey-Boltz L.A., Unsal-Kacmaz K., and Linn S. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem 73 (2004) 39-85
    • (2004) Annu Rev Biochem , vol.73 , pp. 39-85
    • Sancar, A.1    Lindsey-Boltz, L.A.2    Unsal-Kacmaz, K.3    Linn, S.4
  • 31
    • 10744226821 scopus 로고    scopus 로고
    • Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays
    • Nishizuka S., Charboneau L., Young L., Major S., Reinhold W.C., Waltham M., et al. Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays. Proc Natl Acad Sci USA 100 (2003) 14229-14234
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14229-14234
    • Nishizuka, S.1    Charboneau, L.2    Young, L.3    Major, S.4    Reinhold, W.C.5    Waltham, M.6
  • 32
    • 0035984941 scopus 로고    scopus 로고
    • YC-1 increases cyclo-oxygenase-2 expression through protein kinase G- and p44/42 mitogen-activated protein kinase-dependent pathways in A549 cells
    • Chang M.S., Lee W.S., Teng C.M., Lee H.M., Sheu J.R., Hsiao G., et al. YC-1 increases cyclo-oxygenase-2 expression through protein kinase G- and p44/42 mitogen-activated protein kinase-dependent pathways in A549 cells. Br J Pharmacol 136 (2002) 558-567
    • (2002) Br J Pharmacol , vol.136 , pp. 558-567
    • Chang, M.S.1    Lee, W.S.2    Teng, C.M.3    Lee, H.M.4    Sheu, J.R.5    Hsiao, G.6
  • 33
    • 33748188459 scopus 로고    scopus 로고
    • Epidermal growth factor receptor biology in head and neck cancer
    • Kalyankrishna S., and Grandis J.R. Epidermal growth factor receptor biology in head and neck cancer. J Clin Oncol 24 (2006) 2666-2672
    • (2006) J Clin Oncol , vol.24 , pp. 2666-2672
    • Kalyankrishna, S.1    Grandis, J.R.2
  • 34
    • 56049111865 scopus 로고    scopus 로고
    • Drug development against metastasis-related genes and their pathways: a rationale for cancer therapy
    • Iiizumi M., Liu W., Pai S.K., Furuta E., and Watabe K. Drug development against metastasis-related genes and their pathways: a rationale for cancer therapy. Biochim Biophys Acta 1786 (2008) 87-104
    • (2008) Biochim Biophys Acta , vol.1786 , pp. 87-104
    • Iiizumi, M.1    Liu, W.2    Pai, S.K.3    Furuta, E.4    Watabe, K.5
  • 35
    • 0038386613 scopus 로고    scopus 로고
    • Src family kinases in tumor progression and metastasis
    • Summy J.M., and Gallick G.E. Src family kinases in tumor progression and metastasis. Cancer Metastasis Rev 22 (2003) 337-358
    • (2003) Cancer Metastasis Rev , vol.22 , pp. 337-358
    • Summy, J.M.1    Gallick, G.E.2
  • 36
    • 33749244775 scopus 로고    scopus 로고
    • Is caveolin-1 a viable therapeutic target to reduce cancer metastasis?
    • van Golen K.L. Is caveolin-1 a viable therapeutic target to reduce cancer metastasis?. Expert Opin Ther Targets 10 (2006) 709-721
    • (2006) Expert Opin Ther Targets , vol.10 , pp. 709-721
    • van Golen, K.L.1
  • 37
    • 10744230953 scopus 로고    scopus 로고
    • Prognostic significance of tumor angiogenesis, Ki 67, p53 oncoprotein, epidermal growth factor receptor and HER2 receptor protein expression in undifferentiated nasopharyngeal carcinoma-a prospective study
    • Ma B.B., Poon T.C., To K.F., Zee B., Mo F.K., Chan C.M., et al. Prognostic significance of tumor angiogenesis, Ki 67, p53 oncoprotein, epidermal growth factor receptor and HER2 receptor protein expression in undifferentiated nasopharyngeal carcinoma-a prospective study. Head Neck 25 (2003) 864-872
    • (2003) Head Neck , vol.25 , pp. 864-872
    • Ma, B.B.1    Poon, T.C.2    To, K.F.3    Zee, B.4    Mo, F.K.5    Chan, C.M.6
  • 38
    • 4444253496 scopus 로고    scopus 로고
    • Association of E-cadherin and beta-catenin with metastasis in nasopharyngeal carcinoma
    • Li Z., Ren Y., Lin S.X., Liang Y.J., and Liang H.Z. Association of E-cadherin and beta-catenin with metastasis in nasopharyngeal carcinoma. Chin Med J (Engl) 117 (2004) 1232-1239
    • (2004) Chin Med J (Engl) , vol.117 , pp. 1232-1239
    • Li, Z.1    Ren, Y.2    Lin, S.X.3    Liang, Y.J.4    Liang, H.Z.5
  • 39
    • 73449137584 scopus 로고    scopus 로고
    • Overexpression of caveolin-1 in hepatocellular carcinoma with metastasis and worse prognosis: correlation with vascular endothelial growth factor, microvessel density and unpaired artery
    • Zhang Z.B., Cai L., Zheng S.G., Xiong Y., and Dong J.H. Overexpression of caveolin-1 in hepatocellular carcinoma with metastasis and worse prognosis: correlation with vascular endothelial growth factor, microvessel density and unpaired artery. Pathol Oncol Res (2009)
    • (2009) Pathol Oncol Res
    • Zhang, Z.B.1    Cai, L.2    Zheng, S.G.3    Xiong, Y.4    Dong, J.H.5
  • 40
    • 0037083622 scopus 로고    scopus 로고
    • Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage
    • Kato K., Hida Y., Miyamoto M., Hashida H., Shinohara T., Itoh T., et al. Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage. Cancer 94 (2002) 929-933
    • (2002) Cancer , vol.94 , pp. 929-933
    • Kato, K.1    Hida, Y.2    Miyamoto, M.3    Hashida, H.4    Shinohara, T.5    Itoh, T.6
  • 41
    • 40349100358 scopus 로고    scopus 로고
    • Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma
    • Campbell L., Jasani B., Edwards K., Gumbleton M., and Griffiths D.F. Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma. Br J Cancer 98 (2008) 931-940
    • (2008) Br J Cancer , vol.98 , pp. 931-940
    • Campbell, L.1    Jasani, B.2    Edwards, K.3    Gumbleton, M.4    Griffiths, D.F.5
  • 42
    • 0032774407 scopus 로고    scopus 로고
    • Metastasis-related genes in prostate cancer: the role of caveolin-1
    • Thompson T.C. Metastasis-related genes in prostate cancer: the role of caveolin-1. Cancer Metastasis Rev 17 (1998) 439-442
    • (1998) Cancer Metastasis Rev , vol.17 , pp. 439-442
    • Thompson, T.C.1
  • 43
    • 70349235876 scopus 로고    scopus 로고
    • Upregulation of caveolin-1 and CD147 expression in nasopharyngeal carcinoma enhanced tumor cell migration and correlated with poor prognosis of the patients
    • Du Z.M., Hu C.F., Shao Q., Huang M.Y., Kou C.W., Zhu X.F., et al. Upregulation of caveolin-1 and CD147 expression in nasopharyngeal carcinoma enhanced tumor cell migration and correlated with poor prognosis of the patients. Int J Cancer 125 (2009) 1832-1841
    • (2009) Int J Cancer , vol.125 , pp. 1832-1841
    • Du, Z.M.1    Hu, C.F.2    Shao, Q.3    Huang, M.Y.4    Kou, C.W.5    Zhu, X.F.6
  • 44
    • 0038771261 scopus 로고    scopus 로고
    • YC-1 inhibits proliferation of human vascular endothelial cells through a cyclic GMP-independent pathway
    • Hsu H.K., Juan S.H., Ho P.Y., Liang Y.C., Lin C.H., Teng C.M., et al. YC-1 inhibits proliferation of human vascular endothelial cells through a cyclic GMP-independent pathway. Biochem Pharmacol 66 (2003) 263-271
    • (2003) Biochem Pharmacol , vol.66 , pp. 263-271
    • Hsu, H.K.1    Juan, S.H.2    Ho, P.Y.3    Liang, Y.C.4    Lin, C.H.5    Teng, C.M.6
  • 45
    • 21344454920 scopus 로고    scopus 로고
    • YC-1-inhibited proliferation of rat mesangial cells through suppression of cyclin D1-independent of cGMP pathway and partially reversed by p38 MAPK inhibitor
    • Chiang W.C., Teng C.M., Lin S.L., Chen Y.M., Tsai T.J., and Hsieh B.S. YC-1-inhibited proliferation of rat mesangial cells through suppression of cyclin D1-independent of cGMP pathway and partially reversed by p38 MAPK inhibitor. Eur J Pharmacol 517 (2005) 1-10
    • (2005) Eur J Pharmacol , vol.517 , pp. 1-10
    • Chiang, W.C.1    Teng, C.M.2    Lin, S.L.3    Chen, Y.M.4    Tsai, T.J.5    Hsieh, B.S.6
  • 46
    • 0037438777 scopus 로고    scopus 로고
    • Molecular cytogenetic characterization of nasopharyngeal carcinoma cell lines and xenografts by comparative genomic hybridization and spectral karyotyping
    • Wong N., Hui A.B., Fan B., Lo K.W., Pang E., Leung S.F., et al. Molecular cytogenetic characterization of nasopharyngeal carcinoma cell lines and xenografts by comparative genomic hybridization and spectral karyotyping. Cancer Genet Cytogenet 140 (2003) 124-132
    • (2003) Cancer Genet Cytogenet , vol.140 , pp. 124-132
    • Wong, N.1    Hui, A.B.2    Fan, B.3    Lo, K.W.4    Pang, E.5    Leung, S.F.6
  • 47
    • 85068488222 scopus 로고    scopus 로고
    • Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response
    • in press
    • Ma BB, Lui VW, Poon FF, Wong SC, To KF, Wong E, et al. Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response. Invest New Drugs; in press.
    • Invest New Drugs
    • Ma, B.B.1    Lui, V.W.2    Poon, F.F.3    Wong, S.C.4    To, K.F.5    Wong, E.6
  • 48
    • 0029063936 scopus 로고
    • The Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor
    • Miller W.E., Earp H.S., and Raab-Traub N. The Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor. J Virol 69 (1995) 4390-4398
    • (1995) J Virol , vol.69 , pp. 4390-4398
    • Miller, W.E.1    Earp, H.S.2    Raab-Traub, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.