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Volumn 86, Issue 12, 2008, Pages 2784-2791

Memantine leads to behavioral improvement and amyloid reduction in Alzheimer's-disease-model transgenic mice shown as by micromagnetic resonance imaging

Author keywords

Alzheimer's disease; Amyloid; Micromagnetic resonance imaging; NMDA antagonist

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID PRECURSOR PROTEIN; GADOLINIUM PENTETATE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PRESENILIN 1;

EID: 57049085109     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21713     Document Type: Article
Times cited : (110)

References (32)
  • 3
    • 0029924670 scopus 로고    scopus 로고
    • Effects of the uncompetitive NMDA receptor antagonist memantine on hippocampal long-term potentiation, short-term exploratory modulation and spatial memory in awake, freely moving rats
    • Barnes CA, Danysz W, Parsons CG. 1996. Effects of the uncompetitive NMDA receptor antagonist memantine on hippocampal long-term potentiation, short-term exploratory modulation and spatial memory in awake, freely moving rats. Eur J Neurosci 8:565-571.
    • (1996) Eur J Neurosci , vol.8 , pp. 565-571
    • Barnes, C.A.1    Danysz, W.2    Parsons, C.G.3
  • 5
    • 33748746399 scopus 로고    scopus 로고
    • From tau to toxicity: Emerging roles of NMDA receptor in Alzheimer's disease
    • Chohan MO, Iqbal K. 2006. From tau to toxicity: emerging roles of NMDA receptor in Alzheimer's disease. J Alzheimers Dis 10:81-87.
    • (2006) J Alzheimers Dis , vol.10 , pp. 81-87
    • Chohan, M.O.1    Iqbal, K.2
  • 6
    • 0141707078 scopus 로고    scopus 로고
    • The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: Preclinical evidence
    • Danysz W, Parsons CG. 2003. The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence. Int J Geriatr Psychiatry 18:S23-S32.
    • (2003) Int J Geriatr Psychiatry , vol.18
    • Danysz, W.1    Parsons, C.G.2
  • 7
    • 34249672242 scopus 로고    scopus 로고
    • Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
    • De Felice FG, Velasco PT, Lambert MP, Viola K, Fernandez SJ, Ferreira ST, Klein WL. 2007. Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine. J Biol Chem 282:11590-11601.
    • (2007) J Biol Chem , vol.282 , pp. 11590-11601
    • De Felice, F.G.1    Velasco, P.T.2    Lambert, M.P.3    Viola, K.4    Fernandez, S.J.5    Ferreira, S.T.6    Klein, W.L.7
  • 8
    • 34748915821 scopus 로고    scopus 로고
    • Reduction of phosphorylated tau during memantine treatment of Alzheimer's disease
    • Degerman GM, Kilander L, Basun H, Lannfelt L. 2007. Reduction of phosphorylated tau during memantine treatment of Alzheimer's disease. Dement Geriatr Cogn Disord 24:247-252.
    • (2007) Dement Geriatr Cogn Disord , vol.24 , pp. 247-252
    • Degerman, G.M.1    Kilander, L.2    Basun, H.3    Lannfelt, L.4
  • 9
    • 0346995345 scopus 로고    scopus 로고
    • Sex differences in the behavioral response to spatial and object novelty in adult C57BL/6 mice
    • Frick KM, Gresack JE. 2003. Sex differences in the behavioral response to spatial and object novelty in adult C57BL/6 mice. Behav Neurosci 117:1283-1291.
    • (2003) Behav Neurosci , vol.117 , pp. 1283-1291
    • Frick, K.M.1    Gresack, J.E.2
  • 10
    • 3042693940 scopus 로고    scopus 로고
    • Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease
    • Hynd MR, Scott HL, Dodd PR. 2004. Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease. Neurochem Int 45:583-595.
    • (2004) Neurochem Int , vol.45 , pp. 583-595
    • Hynd, M.R.1    Scott, H.L.2    Dodd, P.R.3
  • 11
    • 33846633336 scopus 로고    scopus 로고
    • Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
    • Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, Wood M, Viola KL, Klein WL. 2007. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J Neurosci 27:796-807.
    • (2007) J Neurosci , vol.27 , pp. 796-807
    • Lacor, P.N.1    Buniel, M.C.2    Furlow, P.W.3    Clemente, A.S.4    Velasco, P.T.5    Wood, M.6    Viola, K.L.7    Klein, W.L.8
  • 14
    • 57049164806 scopus 로고    scopus 로고
    • Effects of memantine on the activity of secretase enzymes in human neuroblastoma cells
    • Lahiri DK, Chen D, Alley GM, Banerjee PK. 2006. Effects of memantine on the activity of secretase enzymes in human neuroblastoma cells. Eur Neuropsychopharmacol 16:S483-S484.
    • (2006) Eur Neuropsychopharmacol , vol.16
    • Lahiri, D.K.1    Chen, D.2    Alley, G.M.3    Banerjee, P.K.4
  • 16
    • 34249093924 scopus 로고    scopus 로고
    • Pathologically-activated therapeutics for neuroprotection: Mechanism of NMDA receptor block by memantine and S-nitrosylation
    • Lipton SA. 2007. Pathologically-activated therapeutics for neuroprotection: mechanism of NMDA receptor block by memantine and S-nitrosylation. Curr Drug Targets 8:621-632.
    • (2007) Curr Drug Targets , vol.8 , pp. 621-632
    • Lipton, S.A.1
  • 17
    • 34547382568 scopus 로고    scopus 로고
    • Inflammatory mediators leading to protein misfolding and uncompetitive/fast off-rate drug therapy for neurodegenerative disorders
    • Lipton SA, Gu Z, Nakamura T. 2007. Inflammatory mediators leading to protein misfolding and uncompetitive/fast off-rate drug therapy for neurodegenerative disorders. Int Rev Neurobiol 82:1-27.
    • (2007) Int Rev Neurobiol , vol.82 , pp. 1-27
    • Lipton, S.A.1    Gu, Z.2    Nakamura, T.3
  • 18
    • 20444439628 scopus 로고    scopus 로고
    • In vivo and ex vivo MRI detection of localized and disseminated neural stem cell grafts in the mouse brain
    • Magnitsky S, Watson DJ, Walton RM, Pickup S, Bulte JW, Wolfe JH, Poptani H. 2005. In vivo and ex vivo MRI detection of localized and disseminated neural stem cell grafts in the mouse brain. Neuroimage 26:744-754.
    • (2005) Neuroimage , vol.26 , pp. 744-754
    • Magnitsky, S.1    Watson, D.J.2    Walton, R.M.3    Pickup, S.4    Bulte, J.W.5    Wolfe, J.H.6    Poptani, H.7
  • 19
    • 0037146905 scopus 로고    scopus 로고
    • Neuroprotection by memantine against neurodegeneration induced by beta-amyloid(1-40)
    • Miguel-Hidalgo JJ, Alvarez XA, Cacabelos R, Quack G. 2002. Neuroprotection by memantine against neurodegeneration induced by beta-amyloid(1-40). Brain Res 958:210-221.
    • (2002) Brain Res , vol.958 , pp. 210-221
    • Miguel-Hidalgo, J.J.1    Alvarez, X.A.2    Cacabelos, R.3    Quack, G.4
  • 20
    • 6344247564 scopus 로고    scopus 로고
    • Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease
    • Minkeviciene R, Banerjee P, Tanila H. 2004. Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease. J Pharmacol Exp Ther 311:677-682.
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 677-682
    • Minkeviciene, R.1    Banerjee, P.2    Tanila, H.3
  • 21
    • 0032892343 scopus 로고    scopus 로고
    • Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist - a review of preclinical data
    • Parsons CG, Danysz W, Quack G. 1999. Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist - a review of preclinical data. Neuropharmacology 38:735-767.
    • (1999) Neuropharmacology , vol.38 , pp. 735-767
    • Parsons, C.G.1    Danysz, W.2    Quack, G.3
  • 24
    • 33747423612 scopus 로고    scopus 로고
    • Memantine: A review of its use in Alzheimer's disease
    • Robinson DM, Keating GM. 2006. Memantine: a review of its use in Alzheimer's disease. Drugs 66:1515-1534.
    • (2006) Drugs , vol.66 , pp. 1515-1534
    • Robinson, D.M.1    Keating, G.M.2
  • 25
    • 34347326512 scopus 로고    scopus 로고
    • Disease modifying approaches for Alzheimer's pathology
    • Sadowski M, Wisniewski T. 2007. Disease modifying approaches for Alzheimer's pathology. Curr Pharmaceutic Design 13:1943-1954.
    • (2007) Curr Pharmaceutic Design , vol.13 , pp. 1943-1954
    • Sadowski, M.1    Wisniewski, T.2
  • 26
    • 33845484383 scopus 로고    scopus 로고
    • Blocking the apolipoproteinE/amyloid β interaction reduces the parenchymal and vascular amyloid-β deposition and prevents memory deficit in AD transgenic mice
    • Sadowski M, Pankiewicz J, Scholtzova H, Mehta P, Prelli F, Quarter-main D, Wisniewski T. 2006. Blocking the apolipoproteinE/amyloid β interaction reduces the parenchymal and vascular amyloid-β deposition and prevents memory deficit in AD transgenic mice. Proc Natl Acad Sci U S A 103:18787-18792.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 18787-18792
    • Sadowski, M.1    Pankiewicz, J.2    Scholtzova, H.3    Mehta, P.4    Prelli, F.5    Quarter-main, D.6    Wisniewski, T.7
  • 27
    • 33947314641 scopus 로고    scopus 로고
    • Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
    • Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, Sabatini BL. 2007. Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. J Neurosci 27:2866-2875.
    • (2007) J Neurosci , vol.27 , pp. 2866-2875
    • Shankar, G.M.1    Bloodgood, B.L.2    Townsend, M.3    Walsh, D.M.4    Selkoe, D.J.5    Sabatini, B.L.6
  • 28
    • 42649112757 scopus 로고    scopus 로고
    • Sigurdsson E, Wadghiri YZ, Mosconi L, Blind JA, Knudsen E, Asuni A, Tsui WH, Sadowski M, Turnbull D, de Leon M, Wisniewski T. 2008. A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice. Neurobiol Aging. 29:836-847.
    • Sigurdsson E, Wadghiri YZ, Mosconi L, Blind JA, Knudsen E, Asuni A, Tsui WH, Sadowski M, Turnbull D, de Leon M, Wisniewski T. 2008. A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice. Neurobiol Aging. 29:836-847.
  • 29
    • 33645114692 scopus 로고    scopus 로고
    • Effect of subchronic treatment of memantine, galantamine, and nicotine in the brain of Tg2576 (APPswe) transgenic mice
    • Unger C, Svedberg MM, Yu WF, Hedberg MM, Nordberg A. 2006. Effect of subchronic treatment of memantine, galantamine, and nicotine in the brain of Tg2576 (APPswe) transgenic mice. J Pharmacol Exp Ther 317:30-36.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 30-36
    • Unger, C.1    Svedberg, M.M.2    Yu, W.F.3    Hedberg, M.M.4    Nordberg, A.5
  • 32
    • 34447629569 scopus 로고    scopus 로고
    • Therapeutic approaches for prion and Alzheimer's diseases
    • Wisniewski T, Sigurdsson EM. 2007. Therapeutic approaches for prion and Alzheimer's diseases. FEBS J 274:3784-3798.
    • (2007) FEBS J , vol.274 , pp. 3784-3798
    • Wisniewski, T.1    Sigurdsson, E.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.