Glycosylation pattern of humanized IgG-like bispecific antibody produced by recombinant CHO cells

Applied Microbiology and Biotechnology

Volumn 85, Issue 3, 2010, Pages 535-542

  Kim, Wook Dong ^a   Tokunaga, Miwako ^a   Ozaki, Hiroyuki ^a   Ishibashi, Takuya ^b   Honda, Kohsuke ^a   Kajiura, Hiroyuki ^a   Fujiyama, Kazuhito ^a   Asano, Ryutaro ^c   Kumagai, Izumi ^c   Omasa, Takeshi ^a   Ohtake, Hisao ^a  

^a OSAKA UNIVERSITY   (Japan)

^b Toyobo Biologics Inc   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

Bispecific diabody; Bispecific IgG like antibody; Chinese hamster ovary cells; Glycosylation; Immunoglobulin G

Indexed keywords

ANTI-EGFR; BISPECIFIC DIABODY; CHINESE HAMSTER OVARY CELLS; CHO CELL; DIABODY; HUMAN SERUM; IMMUNOGLOBULIN G; MATRIX-ASSISTED LASER DESORPTION/IONIZATION-TIME-OF-FLIGHT MASS SPECTROMETRY; N-LINKED; NEUTRAL OLIGOSACCHARIDES; OLIGOSACCHARIDE STRUCTURE; SIALYLATION;

BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; DESORPTION; ESTERIFICATION; GLYCOSYLATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; OLIGOSACCHARIDES;

ANTIBODIES;

CD3 ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; IMMUNOGLOBULIN G1; INTERLEUKIN 8 ANTIBODY;

ANTIBODY; BIOCHEMISTRY; HOMINID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SERUM;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CHEMICAL STRUCTURE; CHO CELL; CONTROLLED STUDY; FEMALE; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; SIALYLATION;

ANIMALS; ANTIBODIES, BISPECIFIC; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; CRICETULUS; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN G; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

CRICETULUS GRISEUS;

EID: 74149087566     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-009-2152-z     Document Type: Article

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