Oxidative stress induction by (+)-cordiaquinone J triggers both mitochondria-dependent apoptosis and necrosis in leukemia cells

Chemico-Biological Interactions

Volumn 183, Issue 3, 2010, Pages 369-379

  Marinho Filho, José Delano B ^a   Bezerra, Daniel P ^b   Araújo, Ana J ^a   Montenegro, Raquel C ^a   Pessoa, Claudia ^a   Diniz, Jaécio C ^c   Viana, Francisco A ^c   Pessoa, Otília D L ^d   Silveira, Edilberto R ^d   de Moraes, Manoel O ^a   Costa Lotufo, Letícia V ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

^c DEPARTAMENTO DE FÍSICA   (Brazil)

^d Centro de Ciências   (Brazil)

Author keywords

(+) Cordiaquinone J; Apoptosis; Cytotoxicity; HL 60 cells; Reactive oxygen species

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; ACETYLCYSTEINE; BETA LAPACHONE; BROXURIDINE; CASPASE; CORDIAQUINONE J; DOXORUBICIN; GLUTATHIONE; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CELL STRAIN HL 60; CELL VIABILITY; CONTROLLED STUDY; CORDIA; CORDIA LEUCOCEPHALA; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; ERYTHROCYTE MEMBRANE; HEMOLYSIS; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; MELANOMA CELL; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL;

APOPTOSIS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CORDIA; GLUTATHIONE; HL-60 CELLS; HUMANS; LEUKEMIA; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NAPHTHOQUINONES; NECROSIS; OXIDATIVE STRESS; PLANT ROOTS; REACTIVE OXYGEN SPECIES;

CORDIA LEUCOCEPHALA;

EID: 74149085500     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.11.030     Document Type: Article

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