Pyrogallol-mediated toxicity and natural antioxidants: Triumphs and pitfalls of preclinical findings and their translational limitations

Chemico-Biological Interactions

Volumn 183, Issue 3, 2010, Pages 333-340

  Upadhyay, Ghanshyam ^a   Gupta, Satya Prakash ^a   Prakash, Om ^b   Singh, Mahendra Pratap ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b BANARAS HINDU UNIVERSITY   (India)

Author keywords

Natural antioxidants; Pyrogallol toxicity; Translational limitations; Triumphs and pitfalls

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CURCUMIN; EPIGALLOCATECHIN GALLATE; GANODERMA LUCIDUM EXTRACT; KELCH LIKE ECH ASSOCIATED PROTEIN 1; NITRIC OXIDE; PYROGALLOL; RESORCINOL; RESVERATROL; SILYMARIN; TRANSCRIPTION FACTOR NRF2;

ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; AUTOOXIDATION; CALCIUM CELL LEVEL; CALCIUM CURRENT; CARCINOGENESIS; DNA DAMAGE; GASTROINTESTINAL TOXICITY; GENOTOXICITY; GINGER; HEART PROTECTION; HEPATITIS C; HUMAN; LIPID PEROXIDATION; LIVER DISEASE; LIVER PROTECTION; LIVER REGENERATION; LIVER TOXICITY; MEMBRANE DAMAGE; MUTAGENESIS; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PSORIASIS; REVIEW;

ANIMALS; ANTIOXIDANTS; BRAIN DISEASES; CARDIOVASCULAR DISEASES; DRUG EVALUATION, PRECLINICAL; DRUG-INDUCED LIVER INJURY; DRUGS, CHINESE HERBAL; GASTROINTESTINAL DISEASES; HUMANS; MICE; OXIDATIVE STRESS; PYROGALLOL; RATS;

EID: 74149084352     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.11.028     Document Type: Review

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