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Volumn 53, Issue 1, 2010, Pages 36-46

Immune escape mutations detected within HIV-1 epitopes associated with viral control during treatment interruption

Author keywords

CD8+ T cell responses; HIV immune escape; HIV 1 Gag gene; Neutralizing antibodies; Treatment interruption

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; AZATHIOPRINE; CD4 ANTIGEN; CD8 ANTIGEN; EPITOPE; GAG PROTEIN; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 160; GLYCOPROTEIN GP 41; HLA ANTIGEN CLASS 1; LAMIVUDINE; NEUTRALIZING ANTIBODY; NEVIRAPINE; VIRUS GLYCOPROTEIN;

EID: 74049163820     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e3181c4b885     Document Type: Article
Times cited : (11)

References (36)
  • 1
    • 0034979270 scopus 로고    scopus 로고
    • + T cells in peripheral blood after initiation of highly active antiretroviral therapy
    • + T cells in peripheral blood after initiation of highly active antiretroviral therapy. J Virol. 2001;75: 6508-6516.
    • (2001) J Virol , vol.75 , pp. 6508-6516
    • Casazza, J.P.1    Betts, M.R.2    Picker, L.J.3
  • 2
    • 0032941595 scopus 로고    scopus 로고
    • HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression
    • Pitcher CJ, Quittner C, Peterson DM, et al. HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression. Nat Med. 1999;5:518-525.
    • (1999) Nat Med , vol.5 , pp. 518-525
    • Pitcher, C.J.1    Quittner, C.2    Peterson, D.M.3
  • 3
    • 0006922163 scopus 로고    scopus 로고
    • Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy
    • Ogg GS, Jin X, Bonhoeffer S, et al. Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy. J Virol. 1999;73:797-800.
    • (1999) J Virol , vol.73 , pp. 797-800
    • Ogg, G.S.1    Jin, X.2    Bonhoeffer, S.3
  • 4
    • 0033609174 scopus 로고    scopus 로고
    • Control of HIV despite the discontinuation of antiretroviral therapy
    • Lisziewicz J, Rosenberg E, Lieberman J, et al. Control of HIV despite the discontinuation of antiretroviral therapy. N Engl J Med. 1999;340: 1683-1684.
    • (1999) N Engl J Med , vol.340 , pp. 1683-1684
    • Lisziewicz, J.1    Rosenberg, E.2    Lieberman, J.3
  • 5
    • 0032719664 scopus 로고    scopus 로고
    • HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy
    • Ortiz GM, Nixon DF, Trkola A, et al. HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy. J Clin Invest. 1999;104: R13-R18.
    • (1999) J Clin Invest , vol.104
    • Ortiz, G.M.1    Nixon, D.F.2    Trkola, A.3
  • 6
    • 0033823590 scopus 로고    scopus 로고
    • The effect of highly active antiretroviral therapy on binding and neutralizing antibody responses to human immunodeficiency virus type 1 infection
    • Binley JM, Trkola A, Ketas T, et al. The effect of highly active antiretroviral therapy on binding and neutralizing antibody responses to human immunodeficiency virus type 1 infection. J Infect Dis. 2000;182: 945-949.
    • (2000) J Infect Dis , vol.182 , pp. 945-949
    • Binley, J.M.1    Trkola, A.2    Ketas, T.3
  • 7
    • 0034711393 scopus 로고    scopus 로고
    • Control of SIV rebound through structured treatment interruptions during early infection
    • Lori F, Lewis MG, Xu J, et al. Control of SIV rebound through structured treatment interruptions during early infection. Science. 2000;290: 1591-1593.
    • (2000) Science , vol.290 , pp. 1591-1593
    • Lori, F.1    Lewis, M.G.2    Xu, J.3
  • 8
    • 0034071659 scopus 로고    scopus 로고
    • Structured treatment interruption in chronically HIV-1 infected patients after long-term viral suppression
    • Ruiz L, Martinez-Picado J, Romeu J, et al. Structured treatment interruption in chronically HIV-1 infected patients after long-term viral suppression. AIDS. 2000;14:397-403.
    • (2000) AIDS , vol.14 , pp. 397-403
    • Ruiz, L.1    Martinez-Picado, J.2    Romeu, J.3
  • 9
    • 0036340339 scopus 로고    scopus 로고
    • Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection
    • Yu XG, Addo MM, Rosenberg ES, et al. Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection. J Virol. 2002;76:8690-8701.
    • (2002) J Virol , vol.76 , pp. 8690-8701
    • Yu, X.G.1    Addo, M.M.2    Rosenberg, E.S.3
  • 10
    • 0037108925 scopus 로고    scopus 로고
    • Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection
    • Oxenius A, Price DA, Gunthard HF, et al. Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection. Proc Natl Acad Sci U S A. 2002;99: 13747-13752.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13747-13752
    • Oxenius, A.1    Price, D.A.2    Gunthard, H.F.3
  • 12
    • 51049084622 scopus 로고    scopus 로고
    • Risk for opportunistic disease and death after reinitiating continuous antiretroviral therapy in patients with HIV previously receiving episodic therapy: A randomized trial
    • El-Sadr WM, Grund B, Neuhaus J, et al. Risk for opportunistic disease and death after reinitiating continuous antiretroviral therapy in patients with HIV previously receiving episodic therapy: a randomized trial. Ann Intern Med. 2008;149:289-299.
    • (2008) Ann Intern Med , vol.149 , pp. 289-299
    • El-Sadr, W.M.1    Grund, B.2    Neuhaus, J.3
  • 13
    • 15744361847 scopus 로고    scopus 로고
    • Limited durability of viral control following treated acute HIV infection
    • Kaufmann DE, Lichterfeld M, Altfeld M, et al. Limited durability of viral control following treated acute HIV infection. PLoS Med. 2004;1(2):e36.
    • (2004) PLoS Med , vol.1 , Issue.2
    • Kaufmann, D.E.1    Lichterfeld, M.2    Altfeld, M.3
  • 14
    • 0034785811 scopus 로고    scopus 로고
    • Neutralizing antibodies associated with viremia control in a subset of individuals after treatment of acute human immunodeficiency virus type 1 infection
    • Montefiori DC, Hill TS, Vo HT, et al. Neutralizing antibodies associated with viremia control in a subset of individuals after treatment of acute human immunodeficiency virus type 1 infection. J Virol. 2001;75:10200-10207.
    • (2001) J Virol , vol.75 , pp. 10200-10207
    • Montefiori, D.C.1    Hill, T.S.2    Vo, H.T.3
  • 15
    • 0034727073 scopus 로고    scopus 로고
    • Immune control of HIV-1 after early treatment of acute infection
    • Rosenberg ES, Altfeld M, Poon SH, et al. Immune control of HIV-1 after early treatment of acute infection. Nature. 2000;407:523-526.
    • (2000) Nature , vol.407 , pp. 523-526
    • Rosenberg, E.S.1    Altfeld, M.2    Poon, S.H.3
  • 16
    • 33748428894 scopus 로고    scopus 로고
    • A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection
    • Hecht FM, Wang L, Collier A, et al. A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection. J Infect Dis. 2006;194:725-733.
    • (2006) J Infect Dis , vol.194 , pp. 725-733
    • Hecht, F.M.1    Wang, L.2    Collier, A.3
  • 18
    • 4043176043 scopus 로고    scopus 로고
    • Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides
    • Kaufmann DE, Bailey PM, Sidney J, et al. Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides. J Virol. 2004;78:4463-4477.
    • (2004) J Virol , vol.78 , pp. 4463-4477
    • Kaufmann, D.E.1    Bailey, P.M.2    Sidney, J.3
  • 19
    • 0027968068 scopus 로고
    • Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson JD, Higgins DG, Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994;22:4673-4680.
    • (1994) Nucleic Acids Res , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, Tj.3    Clustal, W.4
  • 20
    • 0037389643 scopus 로고    scopus 로고
    • Rapid evolution of the neutralizing antibody response to HIV type 1 infection
    • Richman DD, Wrin T, Little SJ, et al. Rapid evolution of the neutralizing antibody response to HIV type 1 infection. Proc Natl Acad Sci U S A. 2003;100:4144-4149.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 4144-4149
    • Richman, D.D.1    Wrin, T.2    Little, S.J.3
  • 21
    • 34848864584 scopus 로고    scopus 로고
    • Development of an HIV-1 reference panel of subtype B envelope clones isolated from the plasma of recently infected individuals
    • Schweighardt B, Liu Y, Huang W, et al. Development of an HIV-1 reference panel of subtype B envelope clones isolated from the plasma of recently infected individuals. J Acquir Immune Defic Syndr. 2007;46:1-11.
    • (2007) J Acquir Immune Defic Syndr , vol.46 , pp. 1-11
    • Schweighardt, B.1    Liu, Y.2    Huang, W.3
  • 22
    • 36049027844 scopus 로고    scopus 로고
    • Evolution of human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitopes: Fitness-balanced escape
    • Liu Y, McNevin J, Zhao H, et al. Evolution of human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitopes: fitness-balanced escape. J Virol. 2007;81:12179-12188.
    • (2007) J Virol , vol.81 , pp. 12179-12188
    • Liu, Y.1    McNevin, J.2    Zhao, H.3
  • 23
    • 33645240933 scopus 로고    scopus 로고
    • Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1
    • Martinez-Picado J, Prado JG, Fry EE, et al. Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. J Virol. 2006;80:3617-3623.
    • (2006) J Virol , vol.80 , pp. 3617-3623
    • Martinez-Picado, J.1    Prado, J.G.2    Fry, E.E.3
  • 24
    • 10044227534 scopus 로고    scopus 로고
    • Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope
    • Peyerl FW, Bazick HS, Newberg MH, et al. Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope. J Virol. 2004;78:13901-13910.
    • (2004) J Virol , vol.78 , pp. 13901-13910
    • Peyerl, F.W.1    Bazick, H.S.2    Newberg, M.H.3
  • 25
    • 43949094512 scopus 로고    scopus 로고
    • Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid
    • Schneidewind A, Brockman MA, Sidney J, et al. Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid. J Virol. 2008;82:5594-5605.
    • (2008) J Virol , vol.82 , pp. 5594-5605
    • Schneidewind, A.1    Brockman, M.A.2    Sidney, J.3
  • 26
    • 84857959077 scopus 로고    scopus 로고
    • Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response
    • Troyer RM, McNevin J, Liu Y, et al. Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response. PLoS Pathog. 2009;5:e1000365.
    • (2009) PLoS Pathog , vol.5
    • Troyer, R.M.1    McNevin, J.2    Liu, Y.3
  • 27
    • 41949131678 scopus 로고    scopus 로고
    • Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells
    • Daucher M, Price DA, Brenchley JM, et al. Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells. J Virol. 2008;82:4102-4114.
    • (2008) J Virol , vol.82 , pp. 4102-4114
    • Daucher, M.1    Price, D.A.2    Brenchley, J.M.3
  • 28
    • 0034600786 scopus 로고    scopus 로고
    • HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function
    • Appay V, Nixon DF, Donahoe SM, et al. HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function. J Exp Med. 2000;192:63-75.
    • (2000) J Exp Med , vol.192 , pp. 63-75
    • Appay, V.1    Nixon, D.F.2    Donahoe, S.M.3
  • 29
    • 33646686040 scopus 로고    scopus 로고
    • HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
    • Betts MR, Nason MC, West SM, et al. HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood. 2006;107: 4781-4789.
    • (2006) Blood , vol.107 , pp. 4781-4789
    • Betts, M.R.1    Nason, M.C.2    West, S.M.3
  • 30
    • 33750379870 scopus 로고    scopus 로고
    • Antigen-specific T-cell-mediated immunity after HIV-1 infection: Implications for vaccine control of HIV development
    • Betts MR, Gray CM, Cox JH, et al. Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development. Expert Rev Vaccines. 2006;5:505-516.
    • (2006) Expert Rev Vaccines , vol.5 , pp. 505-516
    • Betts, M.R.1    Gray, C.M.2    Cox, J.H.3
  • 31
    • 4644249757 scopus 로고    scopus 로고
    • Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells
    • Lichterfeld M, Kaufmann DE, Yu XG, et al. Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells. J Exp Med. 2004;200:701-712.
    • (2004) J Exp Med , vol.200 , pp. 701-712
    • Lichterfeld, M.1    Kaufmann, D.E.2    Yu, X.G.3
  • 32
    • 3142559470 scopus 로고    scopus 로고
    • HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha
    • Lichterfeld M, Yu XG, Waring MT, et al. HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha. Blood. 2004;104: 487-494.
    • (2004) Blood , vol.104 , pp. 487-494
    • Lichterfeld, M.1    Yu, X.G.2    Waring, M.T.3
  • 33
    • 55949104717 scopus 로고    scopus 로고
    • Fully differentiated HIV-1 specific CD8+ T effector cells are more frequently detectable in controlled than in progressive HIV-1 infection
    • Addo MM, Draenert R, Rathod A, et al. Fully differentiated HIV-1 specific CD8+ T effector cells are more frequently detectable in controlled than in progressive HIV-1 infection. PLoS ONE. 2007;2(3): e321.
    • (2007) PLoS ONE , vol.2 , Issue.3
    • Addo, M.M.1    Draenert, R.2    Rathod, A.3
  • 34
    • 39349090265 scopus 로고    scopus 로고
    • Measuring HIV-1-specific T cell immunity how valid are current assays?
    • D'Souza MP, Altfeld M. Measuring HIV-1-specific T cell immunity: how valid are current assays? J Infect Dis. 2008;197:337-339.
    • (2008) J Infect Dis , vol.197 , pp. 337-339
    • D'Souza, M.P.1    Altfeld, M.2
  • 35
    • 38149079759 scopus 로고    scopus 로고
    • Aiming for successful vaccine-induced HIV-1-specific cytotoxic T lymphocytes
    • Yang OO. Aiming for successful vaccine-induced HIV-1-specific cytotoxic T lymphocytes. AIDS. 2008;22:325-331.
    • (2008) AIDS , vol.22 , pp. 325-331
    • Yang, O.O.1
  • 36
    • 3843149368 scopus 로고    scopus 로고
    • Tracking the killers: How should we measure CD8 T cells in HIV infection?
    • Lieberman J. Tracking the killers: how should we measure CD8 T cells in HIV infection? AIDS. 2004;18:1489-1493.
    • (2004) AIDS , vol.18 , pp. 1489-1493
    • Lieberman, J.1


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