-
1
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996;87: 159-70.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
2
-
-
0035496104
-
APC, signal transduction and genetic instability in colorectal cancer
-
Fodde R, Smits R, Clevers H. APC, signal transduction and genetic instability in colorectal cancer. Nat Rev Cancer 2001;1: 55-67.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 55-67
-
-
Fodde, R.1
Smits, R.2
Clevers, H.3
-
3
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002;3:415-28.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
4
-
-
0034644655
-
Human colorectal cancers express a constitutively active cholecystokinin-B/ gastrin receptor that stimulates cell growth
-
Hellmich MR, Rui XL, Hellmich HL, Fleming RY, Evers BM, Townsend CM, Jr. Human colorectal cancers express a constitutively active cholecystokinin-B/ gastrin receptor that stimulates cell growth. J Biol Chem 2000;275:32122-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 32122-32128
-
-
Hellmich, M.R.1
Rui, X.L.2
Hellmich, H.L.3
Fleming, R.Y.4
Evers, B.M.5
Townsend Jr., C.M.6
-
5
-
-
0033671373
-
Gastrin and gastrin receptor activation: An early event in the adenoma-carcinoma sequence
-
Smith AM, Watson SA. Gastrin and gastrin receptor activation: an early event in the adenoma-carcinoma sequence. Gut 2000;47:820-4.
-
(2000)
Gut
, vol.47
, pp. 820-824
-
-
Smith, A.M.1
Watson, S.A.2
-
6
-
-
0037183682
-
Potential role of endocrine gastrin in the colonic adenoma carcinoma sequence
-
Watson SA, Morris TM, McWilliams DF, Harris J, Evans S, Smith A, Clarke PA. Potential role of endocrine gastrin in the colonic adenoma carcinoma sequence. Br J Cancer 2002;87:567-73.
-
(2002)
Br J Cancer
, vol.87
, pp. 567-573
-
-
Watson, S.A.1
Morris, T.M.2
McWilliams, D.F.3
Harris, J.4
Evans, S.5
Smith, A.6
Clarke, P.A.7
-
7
-
-
3042676790
-
Gastrins, cholecystokinins and gastrointestinal cancer
-
Aly A, Shulkes A, Baldwin GS. Gastrins, cholecystokinins and gastrointestinal cancer. Biochim Biophys Acta 2004;1704: 1-10.
-
(2004)
Biochim Biophys Acta
, vol.1704
, pp. 1-10
-
-
Aly, A.1
Shulkes, A.2
Baldwin, G.S.3
-
8
-
-
0030821859
-
Rectal cell proliferation and colon cancer risk in patients with hypergastrinaemia
-
Renga M, Brandi G, Paganelli GM, Calabrese C, Papa S, Tosti A, Tomassetti P, Miglioli M, Biasco G. Rectal cell proliferation and colon cancer risk in patients with hypergastrinaemia. Gut 1997; 41:330-2.
-
(1997)
Gut
, vol.41
, pp. 330-332
-
-
Renga, M.1
Brandi, G.2
Paganelli, G.M.3
Calabrese, C.4
Papa, S.5
Tosti, A.6
Tomassetti, P.7
Miglioli, M.8
Biasco, G.9
-
9
-
-
0027293072
-
Chronic endogenous hypergastrinemia in humans: Evidence for a mitogenic effect on the colonic mucosa
-
Sobhani I, Lehy T, Laurent-Puig P, Cadiot G, Ruszniewski P, Mignon M. Chronic endogenous hypergastrinemia in humans: evidence for a mitogenic effect on the colonic mucosa. Gastroenterology 1993;105: 22-30.
-
(1993)
Gastroenterology
, vol.105
, pp. 22-30
-
-
Sobhani, I.1
Lehy, T.2
Laurent-Puig, P.3
Cadiot, G.4
Ruszniewski, P.5
Mignon, M.6
-
10
-
-
0032924189
-
Helicobacter pylori and the risk of colonic adenomas. Colorectal Adenoma Study Group
-
Breuer-Katschinski B, Nemes K, Marr A, Rump B, Leiendecker B, Breuer N, Goebell H. Helicobacter pylori and the risk of colonic adenomas. Colorectal Adenoma Study Group. Digestion 1999;60:210-15.
-
(1999)
Digestion
, vol.60
, pp. 210-215
-
-
Breuer-Katschinski, B.1
Nemes, K.2
Marr, A.3
Rump, B.4
Leiendecker, B.5
Breuer, N.6
Goebell, H.7
-
11
-
-
0024467060
-
Risk for colorectal adenocarcinoma in pernicious anemia. A population-based cohort study
-
Talley NJ, Chute CG, Larson DE, Epstein R, Lydick EG, Melton LJ, III. Risk for colorectal adenocarcinoma in pernicious anemia. A population-based cohort study. Ann Intern Med 1989;111:738-42.
-
(1989)
Ann Intern Med
, vol.111
, pp. 738-742
-
-
Talley, N.J.1
Chute, C.G.2
Larson, D.E.3
Epstein, R.4
Lydick, E.G.5
Melton III, L.J.6
-
12
-
-
0031927720
-
Gastrin and colorectal cancer: A prospective study
-
Thorburn CM, Friedman GD, Dickinson CJ, Vogelman JH, Orentreich N, Parsonnet J. Gastrin and colorectal cancer: a prospective study. Gastroenterology 1998; 115:275-80.
-
(1998)
Gastroenterology
, vol.115
, pp. 275-280
-
-
Thorburn, C.M.1
Friedman, G.D.2
Dickinson, C.J.3
Vogelman, J.H.4
Orentreich, N.5
Parsonnet, J.6
-
13
-
-
0033856281
-
Gastrin is a target of the beta-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis
-
Koh TJ, Bulitta CJ, Fleming JV, Dockray GJ, Varro A, Wang TC. Gastrin is a target of the beta-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis. J Clin Invest 2000;106:533-9.
-
(2000)
J Clin Invest
, vol.106
, pp. 533-539
-
-
Koh, T.J.1
Bulitta, C.J.2
Fleming, J.V.3
Dockray, G.J.4
Varro, A.5
Wang, T.C.6
-
14
-
-
0035863511
-
Hypergastrinemia promotes adenoma progression in the APC(Min-/+) mouse model of familial adenomatous polyposis
-
Watson SA, Smith AM. Hypergastrinemia promotes adenoma progression in the APC(Min-/+) mouse model of familial adenomatous polyposis. Cancer Res 2001; 61:625-31.
-
(2001)
Cancer Res
, vol.61
, pp. 625-631
-
-
Watson, S.A.1
Smith, A.M.2
-
15
-
-
0032708056
-
-
Noble F, Wank SA, Crawley JN, Bradwejn J, Seroogy KB, Hamon M, Roques BP. International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacol Rev 1999;51:745-81.
-
Noble F, Wank SA, Crawley JN, Bradwejn J, Seroogy KB, Hamon M, Roques BP. International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacol Rev 1999;51:745-81.
-
-
-
-
17
-
-
34248589304
-
Role of Annexin-II in GI cancers: Interaction with gastrins/progastrins
-
Singh P. Role of Annexin-II in GI cancers: interaction with gastrins/progastrins. Cancer Lett 2007;252:19-35.
-
(2007)
Cancer Lett
, vol.252
, pp. 19-35
-
-
Singh, P.1
-
18
-
-
74049145127
-
Inactivation of cholecystokinin-2 receptor inhibits progastrin-dependent colonic proliferation and colorectal cancer in mice
-
Jin G, Dubeykovskiy AN, Pritchard DM, Betz KS, Varro A, Wang TC. Inactivation of cholecystokinin-2 receptor inhibits progastrin-dependent colonic proliferation and colorectal cancer in mice. Gastroenterology 2008;134:A115.
-
(2008)
Gastroenterology
, vol.134
-
-
Jin, G.1
Dubeykovskiy, A.N.2
Pritchard, D.M.3
Betz, K.S.4
Varro, A.5
Wang, T.C.6
-
19
-
-
0028795540
-
Development and characterization of normal colonic epithelial cell lines derived from normal mucosa of patients with colon cancer
-
Stauffer JS, Manzano LA, Balch GC, Merriman RL, Tanzer LR, Moyer MP. Development and characterization of normal colonic epithelial cell lines derived from normal mucosa of patients with colon cancer. Am J Surg 1995;169:190-5.
-
(1995)
Am J Surg
, vol.169
, pp. 190-195
-
-
Stauffer, J.S.1
Manzano, L.A.2
Balch, G.C.3
Merriman, R.L.4
Tanzer, L.R.5
Moyer, M.P.6
-
20
-
-
11144224144
-
Efficient functional pseudotyping of oncoretroviral and lentiviral vectors by Venezuelan equine encephalitis virus envelope proteins
-
Kolokoltsov AA, Weaver SC, Davey RA. Efficient functional pseudotyping of oncoretroviral and lentiviral vectors by Venezuelan equine encephalitis virus envelope proteins. J Virol 2005;79:756-63.
-
(2005)
J Virol
, vol.79
, pp. 756-763
-
-
Kolokoltsov, A.A.1
Weaver, S.C.2
Davey, R.A.3
-
21
-
-
0031037150
-
Selective reconstitution of gastrin-releasing peptide receptor with G alpha q
-
Hellmich MR, Battey JF, Northup JK. Selective reconstitution of gastrin-releasing peptide receptor with G alpha q. Proc Natl Acad Sci U S A 1997;94:751-6.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 751-756
-
-
Hellmich, M.R.1
Battey, J.F.2
Northup, J.K.3
-
22
-
-
33847063200
-
Constitutively active CCK2 receptor splice variant increases Srcdependent HIF-1 alpha expression and tumor growth
-
Chao C, Goluszko E, Lee YT, Kolokoltsov AA, Davey RA, Uchida T, Townsend CM, Jr, Hellmich MR. Constitutively active CCK2 receptor splice variant increases Srcdependent HIF-1 alpha expression and tumor growth. Oncogene 2007;26:1013-19.
-
(2007)
Oncogene
, vol.26
, pp. 1013-1019
-
-
Chao, C.1
Goluszko, E.2
Lee, Y.T.3
Kolokoltsov, A.A.4
Davey, R.A.5
Uchida, T.6
Townsend Jr, C.M.7
Hellmich, M.R.8
-
23
-
-
25844457372
-
SRC regulates constitutive internalization and rapid resensitization of a cholecystokinin 2 receptor splice variant
-
Chao C, Ives KL, Goluszko E, Kolokoltsov AA, Davey RA, Townsend CM, Jr, Hellmich MR. SRC regulates constitutive internalization and rapid resensitization of a cholecystokinin 2 receptor splice variant. J Biol Chem 2005;280:33368-73.
-
(2005)
J Biol Chem
, vol.280
, pp. 33368-33373
-
-
Chao, C.1
Ives, K.L.2
Goluszko, E.3
Kolokoltsov, A.A.4
Davey, R.A.5
Townsend Jr, C.M.6
Hellmich, M.R.7
-
24
-
-
17444384884
-
Analysis of the cellular and molecular mechanisms of trophic action of a misspliced form of the type B cholecystokinin receptor present in colon and pancreatic cancer
-
Cheng ZJ, Harikumar KG, Ding WQ, Holicky EL, Miller LJ. Analysis of the cellular and molecular mechanisms of trophic action of a misspliced form of the type B cholecystokinin receptor present in colon and pancreatic cancer. Cancer Lett 2005;222:95-105.
-
(2005)
Cancer Lett
, vol.222
, pp. 95-105
-
-
Cheng, Z.J.1
Harikumar, K.G.2
Ding, W.Q.3
Holicky, E.L.4
Miller, L.J.5
-
25
-
-
25844506681
-
Structure/function of the CCK2/gastrin receptor
-
Merchant JL, eds, Belleville: MedPub Inc
-
Hellmich MR, Hull R, Harper EA. Structure/function of the CCK2/gastrin receptor. In: Merchant JL, eds. Gastrin in the New Millenniumed. Belleville: MedPub Inc., 2004. 71-92.
-
(2004)
Gastrin in the New Millenniumed
, pp. 71-92
-
-
Hellmich, M.R.1
Hull, R.2
Harper, E.A.3
-
26
-
-
0030836306
-
Molecular mechanisms for the growth factor action of gastrin
-
Todisco A, Takeuchi Y, Urumov A, Yamada J, Stepan VM, Yamada T. Molecular mechanisms for the growth factor action of gastrin. Am J Physiol 1997; 273:G891-G898.
-
(1997)
Am J Physiol
, vol.273
-
-
Todisco, A.1
Takeuchi, Y.2
Urumov, A.3
Yamada, J.4
Stepan, V.M.5
Yamada, T.6
-
27
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
29
-
-
29144484693
-
Gastrointestinal hormone receptors in primary human colorectal carcinomas
-
Chao C, Tallman ML, Ives KL, Townsend CM, Jr, Hellmich MR. Gastrointestinal hormone receptors in primary human colorectal carcinomas. J Surg Res 2005;129: 313-21.
-
(2005)
J Surg Res
, vol.129
, pp. 313-321
-
-
Chao, C.1
Tallman, M.L.2
Ives, K.L.3
Townsend Jr, C.M.4
Hellmich, M.R.5
-
30
-
-
0032957050
-
Receptor autoradiographic evaluation of cholecystokinin, neurotensin, somatostatin and vasoactive intestinal peptide receptors in gastro-intestinal adenocarcinoma samples: Where are they really located?
-
Reubi JC, Waser B, Schmassmann A, Laissue JA. Receptor autoradiographic evaluation of cholecystokinin, neurotensin, somatostatin and vasoactive intestinal peptide receptors in gastro-intestinal adenocarcinoma samples: where are they really located? Int J Cancer 1999;81: 376-86.
-
(1999)
Int J Cancer
, vol.81
, pp. 376-386
-
-
Reubi, J.C.1
Waser, B.2
Schmassmann, A.3
Laissue, J.A.4
-
31
-
-
0035805103
-
Gastrininduced DNA synthesis requires p38-MAPK activation via PKC/Ca(2+) and Src-dependent mechanisms
-
Dehez S, Daulhac L, Kowalski-Chauvel A, Fourmy D, Pradayrol L, Seva C. Gastrininduced DNA synthesis requires p38-MAPK activation via PKC/Ca(2+) and Src-dependent mechanisms. FEBS Lett 2001;496:25-30.
-
(2001)
FEBS Lett
, vol.496
, pp. 25-30
-
-
Dehez, S.1
Daulhac, L.2
Kowalski-Chauvel, A.3
Fourmy, D.4
Pradayrol, L.5
Seva, C.6
-
32
-
-
0037073757
-
Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor
-
Guo YS, Cheng JZ, Jin GF, Gutkind JS, Hellmich MR, Townsend CM, Jr. Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor. J Biol Chem 2002;277: 48755-63.
-
(2002)
J Biol Chem
, vol.277
, pp. 48755-48763
-
-
Guo, Y.S.1
Cheng, J.Z.2
Jin, G.F.3
Gutkind, J.S.4
Hellmich, M.R.5
Townsend Jr, C.M.6
-
33
-
-
2342555148
-
Molecular mechanisms of gastrin-dependent gene regulation
-
Hocker M. Molecular mechanisms of gastrin-dependent gene regulation. Ann N Y Acad Sci 2004;1014:97-109.
-
(2004)
Ann N Y Acad Sci
, vol.1014
, pp. 97-109
-
-
Hocker, M.1
-
34
-
-
0037230016
-
Stimulation of gastrin-CCKB receptor promotes migration of gastric AGS cells via multiple paracrine pathways
-
Noble PJ, Wilde G, White MR, Pennington SR, Dockray GJ, Varro A. Stimulation of gastrin-CCKB receptor promotes migration of gastric AGS cells via multiple paracrine pathways. Am J Physiol Gastrointest Liver Physiol 2003;284:G75-G84.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Noble, P.J.1
Wilde, G.2
White, M.R.3
Pennington, S.R.4
Dockray, G.J.5
Varro, A.6
-
35
-
-
0033066686
-
Cell typespecific requirement of the MAPK pathway for the growth factor action of gastrin
-
Stepan VM, Dickinson CJ, del Valle J, Matsushima M, Todisco A. Cell typespecific requirement of the MAPK pathway for the growth factor action of gastrin. Am J Physiol 1999;276: G1363-G1372.
-
(1999)
Am J Physiol
, vol.276
-
-
Stepan, V.M.1
Dickinson, C.J.2
del Valle, J.3
Matsushima, M.4
Todisco, A.5
-
36
-
-
0034485821
-
Phase I/II study of G17-DT, an antigastrin immunogen, in advanced colorectal cancer
-
Smith AM, Justin T, Michaeli D, Watson SA. Phase I/II study of G17-DT, an antigastrin immunogen, in advanced colorectal cancer. Clin Cancer Res 2000;6:4719-24.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4719-4724
-
-
Smith, A.M.1
Justin, T.2
Michaeli, D.3
Watson, S.A.4
-
37
-
-
36549009932
-
Progress in developing cholecystokinin (CCK)/gastrin receptor ligands that have therapeutic potential
-
Berna MJ, Tapia JA, Sancho V, Jensen RT. Progress in developing cholecystokinin (CCK)/gastrin receptor ligands that have therapeutic potential. Curr Opin Pharmacol 2007;7:583-92.
-
(2007)
Curr Opin Pharmacol
, vol.7
, pp. 583-592
-
-
Berna, M.J.1
Tapia, J.A.2
Sancho, V.3
Jensen, R.T.4
-
38
-
-
33646155340
-
Gastrazole (JB95008), a novel CCK2/ gastrin receptor antagonist, in the treatment of advanced pancreatic cancer: Resultsfrom two randomised controlled trials
-
Chau I, Cunningham D, Russell C, Norman AR, Kurzawinski T, Harper P, Harrison P, Middleton G, Daniels F, Hickish T, Prendeville J, Ross PJ, et al. Gastrazole (JB95008), a novel CCK2/ gastrin receptor antagonist, in the treatment of advanced pancreatic cancer: resultsfrom two randomised controlled trials. Br J Cancer 2006;94: 1107-15.
-
(2006)
Br J Cancer
, vol.94
, pp. 1107-1115
-
-
Chau, I.1
Cunningham, D.2
Russell, C.3
Norman, A.R.4
Kurzawinski, T.5
Harper, P.6
Harrison, P.7
Middleton, G.8
Daniels, F.9
Hickish, T.10
Prendeville, J.11
Ross, P.J.12
-
39
-
-
33744804337
-
Cyclooxygenase-2 inhibitors: A painful lesson
-
Sanghi S, MacLaughlin EJ, Jewell CW, Chaffer S, Naus PJ, Watson LE, Dostal DE. Cyclooxygenase-2 inhibitors: a painful lesson. Cardiovasc Hematol Disord Drug Targets 2006;6:85-100.
-
(2006)
Cardiovasc Hematol Disord Drug Targets
, vol.6
, pp. 85-100
-
-
Sanghi, S.1
MacLaughlin, E.J.2
Jewell, C.W.3
Chaffer, S.4
Naus, P.J.5
Watson, L.E.6
Dostal, D.E.7
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