Synthetic atrial natriuretic peptide improves systemic and splanchnic circulation and has a lung-protective effect during endotoxemia in pigs

Anesthesia and Analgesia

Volumn 110, Issue 1, 2010, Pages 141-147

  Sekino, Motohiro ^a   Makita, Tetsuji ^a   Ureshino, Hiroyuki ^b   Sungsam, Cho ^b   Sumikawa, Koji ^b  

^a NAGASAKI UNIVERSITY HOSPITAL   (Japan)

^b NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATRIAL NATRIURETIC FACTOR ALPHA; ENDOTOXIN; SODIUM CHLORIDE; ATRIAL NATRIURETIC FACTOR; ENDOTOXIN, ESCHERICHIA COLI; LIPOPOLYSACCHARIDE; NPPA PROTEIN, HUMAN;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY BLOOD FLOW; ARTICLE; CARBON DIOXIDE TENSION; CONTINUOUS INFUSION; CONTROLLED STUDY; DETERIORATION; DOMESTIC PIG; DRUG EFFECT; ENDOTOXEMIA; EXPERIMENTAL STUDY; FEMALE; FLUID RESUSCITATION; HEART INDEX; HEMODYNAMICS; INTESTINE MUCOSA; INTESTINE PERFUSION; LOW DRUG DOSE; LUNG VENTILATION; LUNG WEDGE PRESSURE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; PROTECTION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RESPIRATORY SYSTEM; SEPSIS; SPLANCHNIC BLOOD FLOW; SUPERIOR MESENTERIC ARTERY; SYSTEMIC CIRCULATION; ANIMAL; BLOOD GAS ANALYSIS; CIRCULATION; LUNG DISEASE; MESENTERIC ARTERY; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PHYSIOLOGY; SWINE;

ANESTHESIA; ANIMALS; ATRIAL NATRIURETIC FACTOR; BLOOD CIRCULATION; BLOOD GAS ANALYSIS; ENDOTOXEMIA; ENDOTOXINS; FEMALE; HEMODYNAMICS; LIPOPOLYSACCHARIDES; LUNG DISEASES; MALE; MESENTERIC ARTERIES; OXYGEN CONSUMPTION; SPLANCHNIC CIRCULATION; SWINE;

EID: 74049108617     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e3181c4ee6c     Document Type: Article

References (32)

1. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001;29:1303-1310
2. Parrillo JE. Pathogenetic mechanisms of septic shock. N Engl J Med 1993;328:1471-1477
3. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL. Surviving Sepsis campaign: International guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008;36:296-327
4. Fiddian-Green RG, Haglund U, Gutierrez G, Shoemaker WC. Goals for the resuscitation of shock. Crit Care Med 1993;21:S25-31
5. Hiltebrand LB, Krejci V, Sigurdsson GH. Effects of dopamine, dobutamine, and dopexamine on microcirculatory blood flow in the gastrointestinal tract during sepsis and anesthesia. Anesthesiology 2004;100:1188-1197
6. Krejci V, Hiltebrand LB, Sigurdsson GH. Effects of epinephrine, norepinephrine, and phenylephrine on microcirculatory blood flow in the gastrointestinal tract in sepsis. Crit Care Med 2006;34:1456-1463
7. Hiltebrand LB, Krejci V, Jakob SM, Takala J, Sigurdsson GH. Effects of vasopressin on microcirculatory blood flow in the gastrointestinal tract in anesthetized pigs in septic shock. Anesthesiology 2007;106:1156-1167
8. Buwalda M, Ince C. Opening the microcirculation: can vasodilators be useful in sepsis? Intensive Care Med 2002;28:1208-1217
9. Oldner A, Wanecek M, Weitzberg E, Rundgren M, Alving K, Ullman J, Rudehill A. Angiotensin II receptor antagonism increases gut oxygen delivery but fails to improve intestinal mucosal acidosis in porcine endotoxin shock. Shock 1999;11:127-135
10. Wiel E, Pu Q, Leclerc J, Corseaux D, Bordet R, Lund N, Jude B, Vallet B. Effects of the angiotensin-converting enzyme inhibitor perindopril on endothelial injury and hemostasis in rabbit endotoxic shock. Intensive Care Med 2004;30:1652-1659
11. Laesser M, Oi Y, Ewert S, Fandriks L, Aneman A. The angiotensin II receptor blocker candesartan improves survival and mesenteric perfusion in acute porcine endotoxin model. Acta Anaesthesiol Scand 2004;48:198-204
12. Floras JS. Sympathoinhibitory effects of atrial natriuretic factor in normal humans. Circulation 1990;81:1860-1873
13. Hayashi M, Tsutamoto T, Wada A, Maeda K, Mabuchi N, Tsutsui T, Horie H, Ohnishi M, Kinoshita M. Intravenous atrial natriuretic peptide prevents left ventricular remodeling in patients with first anterior acute myocardial infarction. J Am Coll Cardiol 2001;37:1820-1826
14. Nishikimi T, Maeda N, Matsuoka H. The role of natriuretic peptides in cardioprotection. Cardiovasc Res 2006;69:318-328
15. Ladetzki-Baehs K, Keller M, Kiemer AK, Koch E, Zahler S, Wendel A, Vollmar AM. Atrial natriuretic peptide, a regulator of nuclear factor B activation in vivo. Endocrinology 2007;148:332-336
16. 2 balance during endotoxemia in pigs. Intensive Care Med 2005;31:985-992
17. Kuniyoshi T, Kakihana Y, Isowaki S, Nagata E, Tobo K, Kaminosono, Hashiguchi T, Tahara M, Kawamae H, Okayama N, Kanmura Y. Effects of olprinone on hepatosplanchnic circulation and mitochondrial oxidation in a porcine model of endotoxemia. J Anesth 2005;19:295-301
18. Toung T, Reilly PM, Fuh KC, Ferris R, Bulkley GB. Mesenteric vasoconstriction in response to hemorrhagic shock. Shock 2000;13:267-273
19. Kuebler JF, Jarrar D, Toth B, Bland KI, Rue L III, Wang P, Chaudry IH. Estradiol administration improves splanchnic perfusion following trauma-hemorrhage and sepsis. Arch Surg 2002;137:74-79
20. Seguin P, Bellissant E, Le Tulzo Y, Laviolle B, Lessard Y, Thomas R, Malledant Y. Effects of epinephrine compared with the combination of dobutamine and norepinephrine on gastric perfusion in septic shock. Clin Pharmacol Ther 2002;71:381-388
21. Wall P, Buising C, Henderson L, Rickers T, Cardenas A, Owens L, Timberlake G, Paradise N. Enalaprilat improves systemic cardiovascular parameters and mesenteric blood flow during hypotensive resuscitation from hemorrhagic shock in dogs. Shock 2002;17:228-233
22. Aneman A, Svensson M, Broome M, Biber B, Petterson A, Fandriks L. Specific angiotensin II receptor blockade improves intestinal perfusion during graded hypovolemia in pigs. Crit Care Med 2000;28:818-823
23. Laesser M, Spak E, Ewert S, Aneman A, Fandriks L. Candesartan improves survival following severe hypovolemia in pigs; a role for the angiotensin II type 2 receptor? Intensive Care Med 2005;31:1109-1115
24. Dubin A, Murias G, Maskin B, Pozo MO, Sottile JP, Baran M, Edul VS, Canales HS, Badie JC, Etcheverry G, Estenssoro E. Increased blood flow prevents intramucosal acidosis in sheep endotoxemia: a controlled study. Crit Care 2005;9:R66-73
25. Tugtekin IF, Radermacher P, Theisen M, Matejovic M, Stehr A, Ploner F, Matura K, Ince C, Georgieff M, Trager K. Increased ileal-mucosal-arterial Pco2 gap is associated with impaired villus microcirculation in endotoxic pigs. Intensive Care Med 2001;27:757-766
26. Mitaka C, Hirata Y, Nagura T, Tsunoda Y, Amaha K. Beneficial effect of atrial natriuretic peptide on pulmonary gas exchange in patients with acute lung injury. Chest 1998;114:223-228
27. Mitaka C, Hirata Y, Habuka K, Narumi Y, Yokoyama K, Makita K, Imai T. Atrial natriuretic peptide improves pulmonary gas exchange by reducing extravascular lung water in canine model with oleic acid-induced pulmonary edema. Crit Care Med 2002;30:1570-1575
28. Traber DL, Flynn JT, Herndon DN, Redl H, Schlag G, Traber LD. Comparison of cardiopulmonary responses to single bolus and continuous infusion of endotoxin in an ovine model. Circ Shock 1989;27:123-138
29. Lui SF, Malik AB. NF-κ B activation as a pathological mechanism of septic shock and inflammation. Am J Physiol Lung Cell Mol Physiol 2006;290:L622-45
30. Gorgen I, Hartung T, Leist M, Niehorster M, Tiegs G, Uhlig S, Weitzel F, Wendel A. Granulocyte colony-stimulating factor treatment protects rodents against lipopolysaccharide-induced toxicity via suppression of systemic tumor necrosis factor-α. J Immunol 1992;149:918-924
31. Reinhart K, Karzai W. Anti-tumor necrosis factor therapy in sepsis: update on clinical trials and lessons learned. Crit Care Med 2001;29:S121-5
32. Konrad D, Oldner A, Rossi P, Wanecek M, Rudehill A, Weitzberg E. Differentiated and dose-related cardiovascular effects of a dual endothelin receptor antagonist in endotoxin shock. Crit Care Med 2004;32:1192-1199