Effects of the angiotensin-converting enzyme inhibitor perindopril on endothelial injury and hemostatin in rabbit endotoxic shock

Intensive Care Medicine

Volumn 30, Issue 8, 2004, Pages 1652-1659

  Wiel, Eric ^a   Pu, Qian ^a   Leclerc, Jérôme ^a   Corseaux, Delphine ^a   Bordet, Régis ^a   Lund, Niels ^b   Jude, Brigitte ^a   Vallet, Benoît ^a  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b UNIVERSITY OF ROCHESTER   (United States)

Author keywords

Ace inhibitor; Endothelium; Endotoxic shock; Lipopolysaccharide; Monocyte; Tissue factor

Indexed keywords

BLOOD CLOTTING FACTOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; PERINDOPRIL; THROMBOPLASTIN;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM INJURY; ESCHERICHIA COLI; HEMOSTASIS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; RABBIT; RANDOMIZATION; SEPTIC SHOCK; SEROTYPE; VASODILATATION;

ANALYSIS OF VARIANCE; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BLOOD GAS ANALYSIS; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HEMOSTASIS; IMMUNOHISTOCHEMISTRY; NG-NITROARGININE METHYL ESTER; PERINDOPRIL; RABBITS; REGRESSION ANALYSIS; SHOCK, SEPTIC; STATISTICS, NONPARAMETRIC;

EID: 4143102412     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Cotran RS, Pober JS (1990) Cytokine-endothelial interactions in inflammation, immunity, and vascular injury. J Am Soc Nephrol 1:225-235
2. Vallet B (1998) Vascular reactivity and tissue oxygenation. Intensive Care Med 24:3-11
3. Astiz ME, Rackow EC (1998) Septic shock. Lancet 351:1501-1505
4. Myers PR, Zhong Q, Jones JJ, Tanner MA, Adams HR, Parker JL (1995) Release of EDRF and NO in ex vivo perfused aorta: inhibition by in vivo E. coli endotoxemia. Am J Physiol Heart Circ Physiol 268:H955-H961
5. Parker JL, Adams HR (1993) Selective inhibition of endothelium-dependent vasodilatation capacity by Escherichia coli endotoxemia. Circ Res 72:539-551
6. Baker CH, Sutton ET (1993) Arteriolar endothelium-dependent vasodilation occurs during endotoxin shock. Am J Physiol Heart Circ Physiol 264:1118-1123
7. Leclerc J, Pu Q, Corseaux D, Haddad E, Decoene C, Bordet R, Six I, Jude B, Vallet B (2000) A single endotoxin injection in the rabbit causes prolonged blood vessel dysfunction and a procoagulant state. Crit Care Med 28:3672-3678
8. Tavernier B, Guarrigue D, Boulle C, Vallet B, Adnet P (1998) Myofilament calcium sensitivity is decreased in skinned cardiac fibres of endotoxin-treated rabbits. Cardiovasc Res 38:472-479
9. Kessler P, Bauersachs J, Busse R, Schini-Kerth VB (1997) Inhibition of inducible NO synthase restores the impaired endothelium-dependent relaxations in isolated arteries exposed to proinflammatory mediators. Arterioscler Thromb Vasc Biol 17:1746-1755
10. Park JL, Chang KM, Lee SH, Shin SH (1996) Protective effect of nitric oxide in an endotoxin-induced septic shock. Am J Surg 171:340-345
11. Becker RHA, Weimer G, Linz W (1991) Preservation of endothelial function by ramipril in rabbits on a long-term atherogenic diet. J Cardiovasc Pharmacol 18 (Suppl 2):110-115
12. Hickey H, Makdissi M, Hyland R, Wilks D, Dusting GJ (1996) Perindopril treatment prevents the loss of endothelial nitric oxide function and development of nitric oxide function and development of neo-intima in rabbits. J Mol Cell Cardiol 28:1985-1994
13. Van Belle E, Vallet B, Auffray JL, Bauters C, Hamon M, McFadden EP, Lablanche JM, Dupuis B, Bertrand ME (1996) NO synthesis is involved in structural and functional effect of ACE inhibitors in injured arteries. Am J Physiol Heart Circ Physiol 270:H298-H305
14. DeJonge A, Tholen MJ, Timmermanns PB (1984) Interaction of angiotensin converting enzyme inhibitors with the sympathetic nervous system. Prog Pharmacol 5:25-38
15. Yang HYT, Erdös EG (1967) Second kinase in human blood plasma. Nature 215:1402-1043
16. McMurray J, Chopra M (1991) Influence of ACE inhibitors on free radicals and reperfusion injury: pharmacological curiosity or therapeutic hope? Br J Clin Pharmacol 31:373-379
17. Monbouli JV, Illiano S, Scott-Burden T, Vanhoutte PM (1992) The potentiation of endothelium-dependent relaxations to bradykinin by angiotensin converting enzyme inhibitors in canine coronary artery involves both endothelium-derived relaxing and contracting factors. Circ Res 71:137-144
18. Napoleone E, Di Santo A, Camera M, Tremoli E, Lorenzet R (2000) Angiotensin-converting enzyme inhibitors downregulate tissue factor synthesis in monocytes. Circ Res 86:139-143
19. Boldt J, Papsdorf M, Kumle B, Piper S, Hempelmann G (1998) Influence of angiotensin-converting enzyme inhibitor enalaprilat on endothelial-derived substances in the critically ill. Crit Care Med 26:1663-1670
20. Gennari R, Alexander JW, Boyce ST, Lilly N, Babcock GF, Cornaggia M (1996) Effects of the angiotensin converting enzyme inhibitor enalapril on bacterial translocation after thermal injury and bacterial challenge. Shock 6:95-100
21. Kincaid EH, Miller PR, Meredith JW, Chang MC (1998) Enalaprilat improves gut perfusion in critically injured patients. Shock 9:79-83
22. Hamon M, Vallet B, Bauters C, Wernert N, McFadden EP, Lablanche JM, Dupuis B, Bertrand M (1994) Long-term oral administration of L-arginine reduces intimai thickening and enhances neoendothelium-dependent acetylcholine-induced relaxation after arterial injury. Circulation 90:1357-1362
23. Carson S (1987) Continuous chromogenic tissue factor assay: comparison to clot-based assays and sensitivity established using pure tissue factor. Thromb Res 47:379-387
24. Corseaux D, Le Tourneau T, Six I, Ezekowitz MD, McFadden EP, Meurice T, Asserman P, Bauters C, Jude B (1998) Enhanced monocyte tissue factor response after experimental balloon angioplasty in hypercholesterolemic rabbit: inhibition with dietary L-arginine. Circulation 98:1776-1782
25. Mulder P, Elfertak L, Richard V, Compagnon P, Devaux B, Henry JP, Scalbert E, Desche P, Mace B, Thuillez C (1996) Peripheral artery structure and endothelial function in heart failure: effect of ACE inhibition. Am J Physiol Heart Circ Physiol 271:H469-H477
26. Frenette PS, Moyna C, Hartwell DW, Lowe JB, Hynes RO, Wagner DD (1998) Platelet-endothelial interactions in inflamed mesenteric venules. Blood 91:1318-1324
27. Warr T, Rao M, Rapaport S (1990) Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway inhibitor activity. Blood 75:1481-1489
28. Gupta RK, Kjeldsen SE, Motley E, Weder AB, Zweifler AJ, Julius S (1991) Platelet function during antihypertensive treatment with quinapril, a novel angiotensin converting enzyme inhibitor. J Cardiovasc Pharmacol 17:13-19
29. Okrucka A, Pechan J, Kratochvilova H (1998) Effect of the angiotensin-converting enzyme (ACE) inhibitor perindopril on endothelial and platelet functions in essential hypertension. Platelets 9:63-67
30. Zhuo J, Casley D, Murone C, Mendelsohn FAO (1997) Acute and chronic in vivo inhibition of angiotensin-converting enzyme by perindopril in the endothelium and adventitia of large arteries and organs of the rabbit. J Cardiovasc Pharmacol 29:297-310
31. Aoki N, Siegfried M, Lefer AM (1989) Anti-EDRF effect of tumor necrosis factor in isolated, perfused cat carotid arteries. Am J Physiol Heart Circ Physiol 256:H1509-H1512
32. Julou-Schaeffer G, Gray GA, Fleming I, Schott C, Parratt JR, Stockt JC (1990) Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway. Am J Physiol Heart Circ Physiol 259:H1038-H1043
33. Rees DD, Monkhouse JE, Cambridge D, Moncada S (1998) Nitric oxide and the haemodynamic profile of endotoxin shock in the conscious mouse. Br J Pharmacol 124:540-546
34. Adeagbo ASO, Triggle CR (1993) Interactions of nitric oxide synthase inhibitors and dexamethasone with α-adrenoceptor-mediated responses in rat. Br J Pharmacol 109:495-501
35. Tiffany CW, Burch RM (1989) Bradykinin stimulates tumor necrosis factor and interleukin-1 release from macrophages. FEBS Lett 247:189-192
36. Daemen MJAP, Lombardi DM, Bosnian FT, Schwartz SM (1991) Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall. Circ Res 68:450-456
37. Chopra M, Beswick M, Clapperton M, Dargie HJ, Smith WE, McMurray J (1992) Antioxidant effect of angiotensin-con verting enzyme (ACE) inhibitors: free radical and oxidant scavenging are sulfhydryl dependent, but lipid peroxidation is inhibited by both sulfhydryl-and nonsulfhydryl-containing ACE inhibitors. J Cardiovasc Pharmacol 19:330-340
38. Matsubara T, Ziff M (1986) Increased superoxide anion release from human endothelial cells in response to cytokines. J Immunol 137:3295-3298
39. Szabó C, Cuzzocrea S, Zinngarelli B, O'Connor M, Salzman AL (1997) Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. J Clin Invest 100:723-735