HPLC determination of novel dithiolethione containing drugs and its application for in vivo studies in rats

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 3-4, 2010, Pages 340-346

  Giustarini, Daniela ^a   Perrino, Elena ^b   Tazzari, Valerio ^b   Rossi, Ranieri ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Aspirin; Diclofenac; Dithiolethione; Sildenafil; Valproic acid

Indexed keywords

CHROMATOGRAPHIC SEPARATIONS; DICLOFENAC; DITHIOLETHIONE; GRADIENT ELUTION; HPLC METHOD; IN-VIVO; INTRAVENOUS ADMINISTRATION; MOBILE PHASE; PHARMACOKINETIC STUDIES; POTENTIAL DRUG; QUANTIFICATION LIMIT; SILDENAFIL; SIMULTANEOUS DETECTION; TRIFLUOROACETIC ACIDS; VALPROIC ACID;

ACETONITRILE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; RATS; SEPARATION;

ACIDS;

5 (4 HYDROXYPHENYL) 3H 1,2 DITHIOLE 3 THIONE; ACETYLSALICYLIC ACID; DICLOFENAC; SILDENAFIL; THIOL DERIVATIVE; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG; VALPROIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; PHARMACEUTICAL PREPARATIONS; RATS; RATS, SPRAGUE-DAWLEY; SPECTROPHOTOMETRY, ULTRAVIOLET; THIONES; THIOPHENES;

RATTUS;

EID: 74049088699     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.11.047     Document Type: Article

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