Investigation of Beckett-Casy model 1: Synthesis of novel 16,17-seco-naltrexone derivatives and their pharmacology

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 3, 2010, Pages 1055-1058

  Imaide, Satomi ^a   Fujii, Hideaki ^a   Watanabe, Akio ^a   Nemoto, Toru ^a   Nakajima, Mayumi ^b   Nakao, Kaoru ^b   Mochizuki, Hidenori ^b   Nagase, Hiroshi ^a  

^a KITASATO UNIVERSITY   (Japan)

^b TORAY INDUSTRIES INC   (Japan)

Author keywords

16,17 seco Naltrexone; Beckett Casy model; Opioid

Indexed keywords

16,17 SECO NALTREXONE; KNT 100; KNT 5; KNT 6; KNT 96; KNT 97; KNT 98; NALTREXONE; NALTREXONE DERIVATIVE; OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CHEMICAL REACTION; DRUG SYNTHESIS; PROCESS MODEL; RECEPTOR AFFINITY; ANALOGS AND DERIVATIVES; CHEMICAL STRUCTURE; COMPARATIVE STUDY; MEDICINAL CHEMISTRY; PROCEDURES; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

CHEMISTRY, PHARMACEUTICAL; MODELS, MOLECULAR; NALTREXONE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 74049085964     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.039     Document Type: Article

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