Synthesis of opioid ligands having oxabicyclo[2.2.2]octane and oxabicyclo[2.2.1]heptane skeletons

Tetrahedron Letters

Volumn 48, Issue 14, 2007, Pages 2547-2553

  Nagase, Hiroshi ^a   Watanabe, Akio ^a   Nemoto, Toru ^a   Yamamoto, Naoshi ^a   Osa, Yumiko ^a   Sato, Noriko ^a   Yoza, Kenji ^b   Kai, Toshitsugu ^a  

^a KITASATO UNIVERSITY   (Japan)

^b BRUKER AXS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4,5 EPOXYMORPHINAN DERIVATIVE; BICYCLO COMPOUND; MORPHINAN DERIVATIVE; OPIATE; OXABICYCLO[2.2.2]HEPTANE DERIVATIVE; OXABICYCLO[2.2.2]OCTANE DERIVATIVE; SULFUR DERIVATIVE; SULFUR YLIDE DERIVATIVE; TAN 821; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DRUG SELECTIVITY; HYDROPHILICITY; LIGAND BINDING; MOLECULAR STABILITY; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; SYNTHESIS;

EID: 33847620822     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.02.022     Document Type: Article

References (11)

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6. Trost B.M., and Melvin L.S. Sulfur Ylides: Emerging Synthetic Intermediates (1975), Academic Press, New York
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8. +.
9. 4: C, 71.52; H, 7.37; N, 3.79. Found: C, 71.69; H, 7.47; N, 3.86.
10. 4: C, 70.96; H, 7.09; N, 3.94. Found: C, 70.86; H, 7.14; N, 3.96.
11. CCDC 630585 contains the supplementary crystallographic data for this Letter. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request/cif.