Governing the monomer-dimer ratio of human cystatin C by single amino acid substitution in the hinge region

Acta Biochimica Polonica

Volumn 56, Issue 3, 2009, Pages 455-463

  Szymańska, Aneta ^a   Radulska, Adrianna ^a   Czaplewska, Paulina ^a   Grubb, Anders ^b   Grzonka, Zbigniew ^a   Rodziewicz Motowidło, Sylwia ^a  

^a UNIVERSITY OF GDA SK   (Poland)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Conformational tension; Dimerization; Hinge loop; Human cystatin C; Point mutation

Indexed keywords

CYSTATIN C;

AMINO ACID SUBSTITUTION; ARTICLE; CHEMISTRY; CIRCULAR DICHROISM; ELECTROPHORESIS; GEL CHROMATOGRAPHY; GENETICS; HUMAN; PHYSIOLOGY; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SUBSTITUTION; CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; CYSTATIN C; ELECTROPHORESIS; HUMANS; MUTAGENESIS, SITE-DIRECTED; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 74049084604     PISSN: 0001527X     EISSN: 1734154X     Source Type: Journal    
DOI: 10.18388/abp.2009_2480     Document Type: Article

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