Sensory contributions to impaired emotion processing in schizophrenia

Schizophrenia Bulletin

Volumn 35, Issue 6, 2009, Pages 1095-1107

  Butler, Pamela D ^a,b,c   Abeles, Ilana Y ^a,c   Weiskopf, Nicole G ^a   Tambini, Arielle ^a   Jalbrzikowski, Maria ^d   Legatt, Michael E ^a,e   Zemon, Vance ^a,e   Loughead, James ^f   Gur, Ruben C ^f   Javitt, Daniel C ^a,b,c  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e YESHIVA UNIVERSITY   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

contrast; gain control; magnocellular; spatial frequency; visual

Indexed keywords

ARTICLE; CONTRAST SENSITIVITY; CORRELATION ANALYSIS; EMOTIONALITY; EVOKED VISUAL RESPONSE; FACIAL EXPRESSION; MAGNOCELLULAR NUCLEUS; PRIORITY JOURNAL; SCHIZOPHRENIA; SPATIAL FREQUENCY DISCRIMINATION; TASK PERFORMANCE; VISUAL DISORDER; ADULT; ATTENTION; DECISION MAKING; EMOTION; FEMALE; GENICULATE BODY; HUMAN; MALE; NERVE CELL; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PATTERN RECOGNITION; PERCEPTION DISORDER; PERCEPTIVE DISCRIMINATION; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; PSYCHOLOGY; PSYCHOPHYSICS; PSYCHOSIS; VISUAL CORTEX; VISUAL SYSTEM;

ADULT; ATTENTION; CONTRAST SENSITIVITY; DECISION MAKING; DISCRIMINATION (PSYCHOLOGY); EMOTIONS; FACIAL EXPRESSION; FEMALE; GENICULATE BODIES; HUMANS; MALE; NEURONS; NEUROPSYCHOLOGICAL TESTS; PATTERN RECOGNITION, VISUAL; PERCEPTUAL DISORDERS; PSYCHOPHYSICS; PSYCHOTIC DISORDERS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; VISUAL CORTEX; VISUAL PATHWAYS;

EID: 73949149661     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbp109     Document Type: Article

References (103)

1. Kraepelin E. Dementia Praecox and Paraphrenia. (Translated by RM Barclay from the 8th German edition) Robertson GM, ed. Edinburgh: Livingstone; 1919.
2. Kring AM, Moran EK. Emotional response deficits in schizophrenia: insights from affective science. Schizophr Bull. 2008;34:819-834.
3. Ochsner KN. The social-emotional processing stream: five core constructs and their translational potential for schizophrenia and beyond. Biol Psychiatry. 2008;64:48-61.
4. Kohler CG, Walker JB, Martin EA, Healey KM, Moberg PJ. Facial emotion perception in schizophrenia: a metaanalytic review. Schizophr Bull. March 27, 2009; doi:10.1093/schbul/sbn192.
5. Edwards J, Jackson HJ, Pattison PE. Emotion recognition via facial expression and affective prosody in schizophrenia: a methodological review. Clin Psychol Rev. 2002; 22:789-832.
6. Kohler CG, Turner TH, Bilker WB, et al. Facial emotion recognition in schizophrenia: intensity effects and error pattern. Am J Psychiatry. 2003;160:1768-1774.
7. Heimberg C, Gur RE, Erwin RJ, Shtasel DL, Gur RC. Facial emotion discrimination: III. Behavioral findings in schizophrenia. Psychiatry Res. 1992;42:253-265.
8. Feinberg TE, Rifkin A, Schaffer C, Walker E. Facial discrimination and emotional recognition in schizophrenia and affective disorders. Arch Gen Psychiatry. 1986;43: 276-279.
9. Sergi MJ, Rassovsky Y, Nuechterlein KH, Green MF. Social perception as a mediator of the influence of early visual processing on functional status in schizophrenia. Am J Psychiatry. 2006;163:448-454.
10. Mueser KT, Doonan R, Penn DL, et al. Emotion recognition and social competence in chronic schizophrenia. J Abnorm Psychol. 1996;105:271-275.
11. Penn DL, Spaulding W, Reed D, Sullivan M. The relationship of social cognition to ward behavior in schizophrenia. Schizophr Res. 1996;20:327-335.
12. Brekke J, Kay DD, Lee KS, Green MF. Biosocial pathways to functional outcome in schizophrenia. Schizophr Res. 2005;80:213-225.
13. Couture SM, Penn DL, Roberts DL. The functional significance of social cognition in schizophrenia: a review. Schizophr Bull. 2006;32(suppl 1):S44-S63.
14. Kohler CG, Gur RC, Gur RE. Emotional processes in schizophrenia: a focus on affective states. In: Borod JC, ed. The Neuropsychology of Emotion. New York, NY: Oxford University Press; 2000:432-455.
15. Kring AM, Kerr SL, Smith DA, Neale JM. Flat affect in schizophrenia does not reflect diminished subjective experience of emotion. J Abnorm Psychol. 1993;102: 507-517.
16. Kring AM, Neale JM. Do schizophrenic patients show a disjunctive relationship among expressive, experiential, and psychophysiological components of emotion? J Abnorm Psychol. 1996;105:249-257.
17. Berenbaum H, Oltmanns TF. Emotional experience and expression in schizophrenia and depression. J Abnorm Psychol. 1992;101:37-44.
18. Mattes RM, Schneider F, Heimann H, Birbaumer N. Reduced emotional response of schizophrenic patients in remission during social interaction. Schizophr Res. 1995; 17:249-255.
19. Aghevli MA, Blanchard JJ, Horan WP. The expression and experience of emotion in schizophrenia: a study of social interactions. Psychiatry Res. 2003;119:261-270.
20. Tremeau F, Malaspina D, Duval F, et al. Facial expressiveness in patients with schizophrenia compared to depressed patients and nonpatient comparison subjects. Am J Psychiatry. 2005;162:92-101.
21. Gur RE, McGrath C, Chan RM, et al. An fMRI study of facial emotion processing in patients with schizophrenia. Am J Psychiatry. 2002;159:1992-1999.
22. Li H, Chan RC, McAlonan GM, Gong QY. Facial emotion processing in schizophrenia: a meta-analysis of functional neuroimaging data. Schizophr Bull. May 20, 2009; doi:10.1093/ schbul/sbn190.
23. Holt DJ, Kunkel L, Weiss AP, et al. Increased medial temporal lobe activation during the passive viewing of emotional and neutral facial expressions in schizophrenia. Schizophr Res. 2006;82:153-162.
24. Schneider F, Gur RC, Koch K, et al. Impairment in the specificity of emotion processing in schizophrenia. Am J Psychiatry. 2006;163:442-447.
25. Turetsky BI, Kohler CG, Indersmitten T, Bhati MT, Charbonnier D, Gur RC. Facial emotion recognition in schizophrenia: when and why does it go awry? Schizophr Res. 2007;94:253-263.
26. Norton D, McBain R, Holt DJ, Ongur D, Chen Y. Association of impaired facial affect recognition with basic facial and visual processing deficits in schizophrenia. Biol Psychiatry. 2009;65:1094-1098.
27. Johnston PJ, Stojanov W, Devir H, Schall U. Functional MRI of facial emotion recognition deficits in schizophrenia and their electrophysiological correlates. Eur J Neurosci. 2005;22:1221-1232.
28. Kerr SL, Neale JM. Emotion perception in schizophrenia: specific deficit or further evidence of generalized poor performance? J Abnorm Psychol. 1993;102:312-318.
29. Kohler CG, Bilker W, Hagendoorn M, Gur RE, Gur RC. Emotion recognition deficit in schizophrenia: association with symptomatology and cognition. Biol Psychiatry. 2000;48:127-136.
30. Salem JE, Kring AM, Kerr SL. More evidence for generalized poor performance in facial emotion perception in schizophrenia. J Abnorm Psychol. 1996;105:480-483.
31. Addington J, Addington D. Facial affect recognition and information processing in schizophrenia and bipolar disorder. Schizophr Res. 1998;32:171-181.
32. Herbener ES, Rosen C, Khine T, Sweeney JA. Failure of positive but not negative emotional valence to enhance memory in schizophrenia. J Abnorm Psychol. 2007;116:43-55.
33. Horan WP, Green MF, Kring AM, Nuechterlein KH. Does anhedonia in schizophrenia reflect faulty memory for subjectively experienced emotions? J Abnorm Psychol. 2006;115:496-508.
34. Burbridge JA, Barch DM. Anhedonia and the experience of emotion in individuals with schizophrenia. J Abnorm Psychol. 2007;116:30-42.
35. Chen Y, Nakayama K, Levy D, Matthysse S, Holzman P. Processing of global, but not local, motion direction is deficient in schizophrenia. Schizophr Res. 2003;61:215-227.
36. Keri S, Kelemen O, Benedek G, Janka Z. Vernier threshold in patients with schizophrenia and in their unaffected siblings. Neuropsychology. 2004;18:537-542.
37. Slaghuis WL, Holthouse T, Hawkes A, Bruno R. Eye movement and visual motion perception in schizophrenia II: global coherent motion as a function of target velocity and stimulus density. Exp Brain Res. 2007;182:415-426.
38. Butler PD, Martinez A, Foxe JJ, et al. Subcortical visual dysfunction in schizophrenia drives secondary cortical impairments. Brain. 2007;130:417-430.
39. Green MF, Nuechterlein KH, Mintz J. Backward masking in schizophrenia and mania. II. Specifying the visual channels. Arch Gen Psychiatry. 1994;51:945-951.
40. Schechter I, Butler PD, Silipo G, Zemon V, Javitt DC. Magnocellular and parvocellular contributions to backward masking dysfunction in schizophrenia. Schizophr Res. 2003;64:91-101.
41. Brenner CA, Wilt MA, Lysaker PH, Koyfman A, ODonnell BF. Psychometrically matched visual-processing tasks in schizophrenia spectrum disorders. J Abnorm Psychol. 2003;112:28-37.
42. Cadenhead KS, Serper Y, Braff DL. Transient versus sustained visual channels in the visual backward masking deficits of schizophrenia patients. Biol Psychiatry. 1998;43:132-138.
43. Martinez A, Hillyard SA, Dias EC, et al. Magnocellular pathway impairment in schizophrenia: evidence from fMRI. J Neurosci. 2008;28:7492-7500.
44. Merigan WH, Maunsell JHR. How parallel are the primate visual pathways? In: Cowan WM, Shooter EM, Stevens CF, Thompson RF, eds. Annual Reviews of Neuroscience. Palo Alto, CA: Annual Reviews, Inc.; 1993:369-402.
45. Schroeder CE, MehtaAD, Givre SJ. A spatiotemporal profile of visual system activation revealed by current source density analysis in the awakemacaque. Cereb Cortex. 1998;8:575-592.
46. Vuilleumier P, Armony JL, Driver J, Dolan RJ. Distinct spatial frequency sensitivities for processing faces and emotional expressions. Nat Neurosci. 2003;6:624-631.
47. Doniger GM, Foxe JJ, Murrary MM, Higgins BA, Javitt DC. Impaired visual object recogntion and dorsal/ventral stream interaction in schizophrenia. Arch Gen Psychiatry. 2002;59:1011-1020.
48. Sehatpour P,Molholm S, Javitt DC, Foxe JJ. Spatiotemporal dynamics of human object recognition processing: an integrated high-density electrical mapping and functional imaging study of "closure" processes. Neuroimage. 2006;29:605-618.
49. Sehatpour P, Molholm S, Schwartz TH, et al. A human intracranial study of long-range oscillatory coherence across a frontal-occipital-hippocampal brain network during visual object processing. Proc Natl Acad Sci U S A. 2008;105: 4399-4404.
50. Bar M, Kassam KS, Ghuman AS, et al. Top-down facilitation of visual recognition. Proc Natl Acad Sci U S A. 2006;103:449-454.
51. Kveraga K, Boshyan J, Bar M. Magnocellular projections as the trigger of top-down facilitation in recognition. J Neurosci. 2007;27:13232-13240.
52. LeggeG. Sustained and transientmechanisms in human vision: temporal and spatial properties. Vision Res. 1978;18:69-82.
53. Kaplan E. The M, P, and K pathways of the primate visual system. In: Chalupa LM, Werner JS, eds. The Visual Neurosciences. Vol.1. Cambridge, MA: MIT Press; 2003.
54. Tootell RB, Silverman MS, Hamilton SL, Switkes E, De Valois RL. Functional anatomy of macaque striate cortex. V. Spatial frequency. J Neurosci. 1988;8:1610-1624.
55. Derrington AM, Lennie P. Spatial and temporal contrast sensitivities of neurones in lateral geniculate nucleus of macaque. J Physiol. 1984;357:219-240.
56. Levitt JB, Schumer RA, Sherman SM, Spear PD, Movshon JA. Visual response properties of neurons in the LGN of normally reared and visually deprived macaque monkeys. J Neurophysiol. 2001;85:2111-2129.
57. Schyns PG, Oliva A. Dr. Angry and Mr. Smile: when categorization flexibly modifies the perception of faces in rapid visual presentations. Cognition. 1999;69:243-265.
58. Pourtois G, Dan ES, Grandjean D, Sander D, Vuilleumier P. Enhanced extrastriate visual response to bandpass spatial frequency filtered faces: time course and topographic evokedpotentials mapping. Hum Brain Mapp. 2005;26:65-79.
59. Kaplan E, Shapley R. The primate retina contains two types of ganglion cells, with high and low contrast sensitivity. Proc Natl Acad Sci U S A. 1986;83:2755-2757.
60. Kaplan E. The receptive field structure of retinal ganglion cells in cat and monkey. In: Leventhal AG, ed. Vision and Visual Dysfunction. Boston, MA: CRC Press; 1991:10-40.
61. Zemon V, Gordon J. Luminance-contrast mechanisms in humans: visual evoked potentials and a nonlinear model. Vision Res. 2006;46:4163-4180.
62. Tootell RB, Hamilton SL, Switkes E. Functional anatomy of macaque striate cortex. IV. Contrast and magno-parvo streams. J Neurosci. 1988;8:1594-1609.
63. Lalor EC, Foxe JJ. Visual evoked spread spectrum analysis (VESPA) responses to stimuli biased towards magnocellular and parvocellular pathways. Vision Res. 2009;49: 127-133.
64. Battista J, Badcock DR, McKendrick AM. Spatial summation properties for magnocellular and parvocellular pathways in glaucoma. Invest Ophthalmol Vis Sci. 2009; 50:1221-1226.
65. Barnett KJ, Foxe JJ, Molholm S, et al. Differences in early sensory-perceptual processing in synesthesia: a visual evoked potential study. Neuroimage. 2008;43:605-613.
66. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Edition. New York, NY: New York State Psychiatric Institute; 1997.
67. Hollingshead AB. Four Factor Index of Social Status. New Haven, CT: Yale University Department of Sociology; 1975.
68. Overall JE, Gorham DR. The brief psychiatric rating scale. Psychol Rep. 1962;10:799-812.
69. Andreasen NC. The scale for the assessment of negative symptoms (SANS). Iowa City, IA: The University of Iowa; 1984.
70. Hyman SE, Arana GW, Rosenbaum JF. Handbook of Psychiatric Drug Therapy. Boston, MA: Little, Brown and Company; 1995.
71. Peuskens J, Link CG. A comparison of quetiapine and chlorpromazine in the treatment of schizophrenia. Acta Psychiatr Scand. 1997;96:265-273.
72. Jibson MD, Tandon R. New atypical antipsychotic medications. J Psychiatr Res. 1998;32:215-228.
73. Woods SW. Chlorpromazine equivalent doses for the newer atypical antipsychotics. J Clin Psychiatry. 2003;64:663-667.
74. Butler PD, Zemon V, Schechter I, et al. Early-stage visual processing and cortical amplification deficits in schizophrenia. Arch Gen Psychiatry. 2005;62:495-504.
75. Gur RE, Nimgaonkar VL, Almasy L, et al. Neurocognitive endophenotypes in a multiplex multigenerational family study of schizophrenia. Am J Psychiatry. 2007;164:813-819.
76. Carter CS, Barch DM, Gur R, Gur R, Pinkham A, Ochsner K. CNTRICS final task selection: social cognitive and affective neuroscience-based measures. Schizophr Bull. 2009;35:153-162.
77. Silver H, Shlomo N, Turner T, Gur RC. Perception of happy and sad facial expressions in chronic schizophrenia: evidence for two evaluative systems. Schizophr Res. 2002;55:171-177.
78. Ekman P, Friesen WV. Pictures of Facial Affect. Palo Alto, CA: Consulting Psychologists Press; 1976.
79. Ojanpaa H, Nasanen R. Utilisation of spatial frequency information in face search. Vision Res. 2003;43:2505-2515.
80. Victor JD, Mast J. A new statistic for steady-state evoked potentials. Electroencephalogr Clin Neurophysiol. 1991; 78:378-388.
81. Zemon V, Hartmann EE, Gordon J, Prunte-Glowazki A. An electrophysiological technique for assessment of the development of spatial vision. Optom Vis Sci. 1997;74:708-716.
82. Butler PD, Schechter I, Zemon V, et al. Dysfunction of early stage visual processing in schizophrenia. Am J Psychiatry. 2001;158:1126-1133.
83. Nestor PG, Faux SF, McCarley RW, Shenton ME, Sands SF. Measurement of visual sustained attention in schizophrenia using signal detection analysis and a newly developed computerized CPT task. Schizophr Res. 1990;3:329-332.
84. Grier JB. Nonparametric indexes for sensitivity and bias: computing formulas. Psychol Bull. 1971;75:424-429.
85. Brenner CA, Krishnan GP, Vohs JL, et al. Steady state responses: Electrophysiological assessment of sensory function in schizophrenia. Schizophr Bull. September 2, 2009; doi:10.1093/schbul/sbp091.
86. Yoon JH, Rokem AS, Silver MA, Minzenberg MJ, Ursa S, Ragland JD, et al. Diminished orientation-specific surround suppression of visual processing in schizophrenia. July 20, 2009; doi:10.1093/schbul/sbp064.
87. ODonnell BF, Potts GF, Nestor PG, Stylianopoulos KC, Shenton ME, McCarley RW. Spatial frequency discrimination in schizophrenia. J Abnorm Psychol. 2002;111:620-625.
88. Javitt DC. When doors of perception close: bottom-up models of disrupted cognition in schizophrenia. Annu Rev Clin Psychol. 2009;5:249-275.
89. Pinkham AE, Sasson NJ, Calkins ME, et al. The other-race effect in face processing among African American and Caucasian individuals with schizophrenia. Am J Psychiatry. 2008;165:639-645.
90. Keri S, Antal A, Szekeres G, Benedek G, Janka Z. Spatiotemporal visual processing in schizophrenia. J Neuropsychiatry Clin Neurosci. 2002;14:190-196.
91. Slaghuis WL, Curran CE. Spatial frequency masking in positive- and negative-symptom schizophrenia. J Abnorm Psychol. 1999;108:42-50.
92. Javitt DC. Intracortical mechanisms of mismatch negativity dysfunction in schizophrenia. Audiol Neurootol. 2000;5: 207-215.
93. Adolphs R, Gosselin F, Buchanan TW, Tranel D, Schyns P, Damasio AR. A mechanism for impaired fear recognition after amygdala damage. Nature. 2005;433:68-72.
94. Sligte IG, Scholte HS, Lamme VA. V4 activity predicts the strength of visual short-term memory representations. J Neurosci. 2009;29:7432-7438.
95. Bednarek DB, Tarnowski A, Grabowska A. Latencies of stimulus-driven eye movements are shorter in dyslexic subjects. Brain Cogn. 2006;60:64-69.
96. Kirchner H, Barbeau EJ, Thorpe SJ, Regis J, Liegeois- Chauvel C. Ultra-rapid sensory responses in the human frontal eye field region. J Neurosci. 2009;29:7599-7606.
97. Kim D, Wylie G, Pasternak R, Butler PD, Javitt DC. Magnocellular contributions to impaired motion processing in schizophrenia. Schizophr Res. 2006;82:1-8.
98. Revheim N, Butler PD, Schechter I, Jalbrzikowski M, Silipo G, Javitt DC. Reading impairment and visual processing deficits in schizophrenia. Schizophr Res. 2006; 87:238-245.
99. Schyns PG, Petro LS, Smith ML. Transmission of facial expressions of emotion co-evolved with their efficient decoding in the brain: behavioral and brain evidence. PLoS ONE. 2009;4:e5625.
100. Yeap S, Kelly SP, Sehatpour P, et al. Early visual sensory deficits as endophenotypes for schizophrenia: high-density electrical mapping in clinically unaffected first-degree relatives. Arch Gen Psychiatry. 2006;63:1180-1188.
101. Leitman DI, Foxe JJ, Butler PD, Saperstein A, Revheim N, Javitt DC. Sensory contributions to impaired prosodic processing in schizophrenia. Biol Psychiatry. 2005;58:56-61.
102. Leitman DI, Hoptman MJ, Foxe JJ, et al. The neural substrates of impaired prosodic detection in schizophrenia and its sensorial antecedents. Am J Psychiatry. 2007; 164:474-482.
103. Adcock RA, Dale C, Fisher M, et al. When top-down meets bottom-up: Auditory training enhances verbal memory in schizophrenia. Schizophr Bull. September 10, 2009; doi:10.1093/schbul/sbp068