메뉴 건너뛰기




Volumn 29, Issue 11, 2009, Pages 1874-1882

Foxp3 regulates megakaryopoiesis and platelet function

Author keywords

Foxp3; IPEX; Megakaryocytes; Platelets

Indexed keywords

CD40 LIGAND; MESSENGER RNA; THROMBOXANE B2; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

EID: 73949145667     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.193805     Document Type: Article
Times cited : (11)

References (54)
  • 4
    • 16844363097 scopus 로고    scopus 로고
    • A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
    • Fontenot JD, Rudensky AY. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat Immunol. 2005;6:331-337.
    • (2005) Nat Immunol , vol.6 , pp. 331-337
    • Fontenot, J.D.1    Rudensky, A.Y.2
  • 5
    • 0041931076 scopus 로고    scopus 로고
    • Foxp3 and natural regulatory T cells: Key to a cell lineage?
    • Ramsdell F. Foxp3 and natural regulatory T cells: key to a cell lineage? Immunity. 2003;19:165-168.
    • (2003) Immunity , vol.19 , pp. 165-168
    • Ramsdell, F.1
  • 8
    • 0025317650 scopus 로고
    • The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome
    • Lyon MF, Peters J, Glenister PH, Ball S, Wright E. The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome. Proc Natl Acad Sci USA. 1990; 87:2433-2437.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2433-2437
    • Lyon, M.F.1    Peters, J.2    Glenister, P.H.3    Ball, S.4    Wright, E.5
  • 9
    • 0036346861 scopus 로고    scopus 로고
    • Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
    • Wildin RS, Smyk-Pearson S, Filipovich AH. Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome. J Med Genet. 2002;39:537-545.
    • (2002) J Med Genet , vol.39 , pp. 537-545
    • Wildin, R.S.1    Smyk-Pearson, S.2    Filipovich, A.H.3
  • 10
    • 0022353446 scopus 로고
    • Establishment of a novel human megakaryoblastic leukemia cell line, MEG-01, with positive Philadelphia chromosome
    • Ogura M, Morishima Y, Ohno R, Kato Y, Hirabayashi N, Nagura H, Saito H. Establishment of a novel human megakaryoblastic leukemia cell line, MEG-01, with positive Philadelphia chromosome. Blood. 1985;66: 1384-1392.
    • (1985) Blood , vol.66 , pp. 1384-1392
    • Ogura, M.1    Morishima, Y.2    Ohno, R.3    Kato, Y.4    Hirabayashi, N.5    Nagura, H.6    Saito, H.7
  • 11
    • 0025636017 scopus 로고
    • M-07e human leukemic factor-dependent cell line provides a rapid and sensitive bioassay for the human cytokines GM-CSF and IL-3
    • Avanzi GC, Brizzi MF, Giannotti J, Ciarletta A, Yang YC, Pegoraro L, Clark SC. M-07e human leukemic factor-dependent cell line provides a rapid and sensitive bioassay for the human cytokines GM-CSF and IL-3. J Cell Physiol. 1990;145:458-464.
    • (1990) J Cell Physiol , vol.145 , pp. 458-464
    • Avanzi, G.C.1    Brizzi, M.F.2    Giannotti, J.3    Ciarletta, A.4    Yang, Y.C.5    Pegoraro, L.6    Clark, S.C.7
  • 13
    • 56149106105 scopus 로고    scopus 로고
    • Cigarette smoke-induced expression of heme oxygenase-1 in human lung fibroblasts is regulated by intracellular glutathione
    • Baglole CJ, Sime PJ, Phipps RP. Cigarette smoke-induced expression of heme oxygenase-1 in human lung fibroblasts is regulated by intracellular glutathione. Am J Physiol Lung Cell Mol Physiol. 2008;295:L624-L636.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295
    • Baglole, C.J.1    Sime, P.J.2    Phipps, R.P.3
  • 14
  • 16
    • 0034192702 scopus 로고    scopus 로고
    • A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation
    • Means GD, Toy DY, Baum PR, Derry JM. A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation. Genomics. 2000;65:213-223.
    • (2000) Genomics , vol.65 , pp. 213-223
    • Means, G.D.1    Toy, D.Y.2    Baum, P.R.3    Derry, J.M.4
  • 17
    • 0026178213 scopus 로고
    • X-linked lymphoreticular disease in the scurfy (sf) mutant mouse
    • Godfrey VL, Wilkinson JE, Russell LB. X-linked lymphoreticular disease in the scurfy (sf) mutant mouse. Am J Pathol. 1991;138:1379-1387.
    • (1991) Am J Pathol , vol.138 , pp. 1379-1387
    • Godfrey, V.L.1    Wilkinson, J.E.2    Russell, L.B.3
  • 18
    • 0001166375 scopus 로고
    • Exceptional inheritance of a sex-linked gene in the mouse explained on the basis that the X/O Sex-chromosome constitution is female
    • Russell WL, Russell LB, Gower JS. Exceptional inheritance of a sex-linked gene in the mouse explained on the basis that the X/O Sex-chromosome constitution is female. Proc Natl Acad Sci USA. 1959;45: 554-560.
    • (1959) Proc Natl Acad Sci USA , vol.45 , pp. 554-560
    • Russell, W.L.1    Russell, L.B.2    Gower, J.S.3
  • 21
    • 4444363344 scopus 로고    scopus 로고
    • Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes
    • Akbiyik F, Ray DM, Gettings KF, Blumberg N, Francis CW, Phipps RP. Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes. Blood. 2004;104:1361-1368.
    • (2004) Blood , vol.104 , pp. 1361-1368
    • Akbiyik, F.1    Ray, D.M.2    Gettings, K.F.3    Blumberg, N.4    Francis, C.W.5    Phipps, R.P.6
  • 22
    • 38349166623 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles
    • Ray DM, Spinelli SL, Pollock SJ, Murant TI, O'Brien JJ, Blumberg N, Francis CW, Taubman MB, Phipps RP. Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles. Thromb Haemost. 2008;99:86-95.
    • (2008) Thromb Haemost , vol.99 , pp. 86-95
    • Ray, D.M.1    Spinelli, S.L.2    Pollock, S.J.3    Murant, T.I.4    O'Brien, J.J.5    Blumberg, N.6    Francis, C.W.7    Taubman, M.B.8    Phipps, R.P.9
  • 23
    • 13344295095 scopus 로고    scopus 로고
    • Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor
    • Savage B, Saldivar E, Ruggeri ZM. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell. 1996;84:289-297.
    • (1996) Cell , vol.84 , pp. 289-297
    • Savage, B.1    Saldivar, E.2    Ruggeri, Z.M.3
  • 26
    • 0021997189 scopus 로고
    • Alterations in neural crest migration by a monoclonal antibody that affects cell adhesion
    • Bronner-Fraser M. Alterations in neural crest migration by a monoclonal antibody that affects cell adhesion. J Cell Biol. 1985;101:610-617.
    • (1985) J Cell Biol , vol.101 , pp. 610-617
    • Bronner-Fraser, M.1
  • 27
    • 0022895355 scopus 로고
    • A novel cadherin cell adhesion molecule: Its expression patterns associated with implantation and organogenesis of mouse embryos
    • Nose A, Takeichi M. A novel cadherin cell adhesion molecule: its expression patterns associated with implantation and organogenesis of mouse embryos. J Cell Biol. 1986;103:2649-2658.
    • (1986) J Cell Biol , vol.103 , pp. 2649-2658
    • Nose, A.1    Takeichi, M.2
  • 28
    • 0027759658 scopus 로고
    • Usefulness of the mean platelet volume
    • Threatte GA. Usefulness of the mean platelet volume. Clin Lab Med. 1993;13:937-950.
    • (1993) Clin Lab Med , vol.13 , pp. 937-950
    • Threatte, G.A.1
  • 29
    • 0035675798 scopus 로고    scopus 로고
    • IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena
    • Bennett CL, Ochs HD. IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena. Curr Opin Pediatr. 2001;13: 533-538.
    • (2001) Curr Opin Pediatr , vol.13 , pp. 533-538
    • Bennett, C.L.1    Ochs, H.D.2
  • 32
    • 35448930435 scopus 로고    scopus 로고
    • Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype
    • Tran DQ, Ramsey H, Shevach EM. Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype. Blood. 2007;110:2983-2990.
    • (2007) Blood , vol.110 , pp. 2983-2990
    • Tran, D.Q.1    Ramsey, H.2    Shevach, E.M.3
  • 34
    • 45949099261 scopus 로고    scopus 로고
    • Cutting edge: Broad expression of the FoxP3 locus in epithelial cells: A caution against early interpretation of fatal inflammatory diseases following in vivo depletion of FoxP3-expressing cells
    • Chen GY, Chen C, Wang L, Chang X, Zheng P, Liu Y. Cutting edge: Broad expression of the FoxP3 locus in epithelial cells: a caution against early interpretation of fatal inflammatory diseases following in vivo depletion of FoxP3-expressing cells. J Immunol. 2008;180:5163-5166.
    • (2008) J Immunol , vol.180 , pp. 5163-5166
    • Chen, G.Y.1    Chen, C.2    Wang, L.3    Chang, X.4    Zheng, P.5    Liu, Y.6
  • 38
    • 37149018400 scopus 로고    scopus 로고
    • FOXP3 actively represses transcription by recruiting the HAT/HDAC complex
    • Li B, Greene MI. FOXP3 actively represses transcription by recruiting the HAT/HDAC complex. Cell Cycle. 2007;6:1432-1436.
    • (2007) Cell Cycle , vol.6 , pp. 1432-1436
    • Li, B.1    Greene, M.I.2
  • 39
    • 17044393922 scopus 로고    scopus 로고
    • Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells
    • Bettelli E, Dastrange M, Oukka M. Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A. 2005;102: 5138-5143.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 5138-5143
    • Bettelli, E.1    Dastrange, M.2    Oukka, M.3
  • 42
    • 0036372440 scopus 로고    scopus 로고
    • Transforming growth factor-beta in T-cell biology
    • Gorelik L, Flavell RA. Transforming growth factor-beta in T-cell biology. Nat Rev Immunol. 2002;2:46-53.
    • (2002) Nat Rev Immunol , vol.2 , pp. 46-53
    • Gorelik, L.1    Flavell, R.A.2
  • 43
    • 0037013930 scopus 로고    scopus 로고
    • Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation
    • Gorelik L, Constant S, Flavell RA. Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation. J Exp Med. 2002;195:1499-1505.
    • (2002) J Exp Med , vol.195 , pp. 1499-1505
    • Gorelik, L.1    Constant, S.2    Flavell, R.A.3
  • 44
    • 0037143597 scopus 로고    scopus 로고
    • Platelet-derived CD40L: The switch-hitting player of cardiovascular disease
    • Andre P, Nannizzi-Alaimo L, Prasad SK, Phillips DR. Platelet-derived CD40L: the switch-hitting player of cardiovascular disease. Circulation. 2002;106:896-899.
    • (2002) Circulation , vol.106 , pp. 896-899
    • Andre, P.1    Nannizzi-Alaimo, L.2    Prasad, S.K.3    Phillips, D.R.4
  • 45
    • 0037456735 scopus 로고    scopus 로고
    • CD40 ligand-assessing risk instead of damage?
    • Freedman JE. CD40 ligand-assessing risk instead of damage? N Engl J Med. 2003;348:1163-1165.
    • (2003) N Engl J Med , vol.348 , pp. 1163-1165
    • Freedman, J.E.1
  • 47
    • 0032227812 scopus 로고    scopus 로고
    • McDevitt MA Transcription factor GATA-1 in megakaryocyte development
    • Orkin SH, Shivdasani RA, Fujiwara Y, McDevitt MA Transcription factor GATA-1 in megakaryocyte development. Stem Cells. 1998;16: 79-83.
    • (1998) Stem Cells , vol.16 , pp. 79-83
    • Orkin, S.H.1    Shivdasani, R.A.2    Fujiwara, Y.3
  • 48
    • 34648826759 scopus 로고    scopus 로고
    • Pathogenesis of chronic immune thrombocytopenic purpura
    • DOI 10.1097/MOH.0b013e3282ba5552, PII 0006275220070900000016
    • Cines DB, McMillan R. Pathogenesis of chronic immune thrombocy-topenic purpura. Curr Opin Hematol. 2007;14:511-514. (Pubitemid 47457642)
    • (2007) Current Opinion in Hematology , vol.14 , Issue.5 , pp. 511-514
    • Cines, D.B.1    McMillan, R.2
  • 50
    • 33845540426 scopus 로고    scopus 로고
    • Submyeloablative cord blood transplantation corrects clinical defects seen in IPEX syndrome
    • Lucas KG, Ungar D, Comito M, Bayerl M, Groh B. Submyeloablative cord blood transplantation corrects clinical defects seen in IPEX syndrome. Bone Marrow Transplant. 2007;39:55-56.
    • (2007) Bone Marrow Transplant , vol.39 , pp. 55-56
    • Lucas, K.G.1    Ungar, D.2    Comito, M.3    Bayerl, M.4    Groh, B.5
  • 51
    • 23944434690 scopus 로고    scopus 로고
    • Enhanced platelet activation in patients with atopic eczema/dermatitis syndrome
    • Kasperska-Zaj CA, Nowakowski M, Rogala B. Enhanced platelet activation in patients with atopic eczema/dermatitis syndrome. Inflammation. 2004;28:299-302.
    • (2004) Inflammation , vol.28 , pp. 299-302
    • Kasperska-Zaj, C.A.1    Nowakowski, M.2    Rogala, B.3
  • 52
    • 59549102474 scopus 로고    scopus 로고
    • Elevated platelet activation in patients with atopic dermatitis and psoriasis: Increased plasma levels of beta-thromboglobulin and platelet factor 4
    • Tamagawa-Mineoka R, Katoh N, Ueda E, Masuda K, Kishimoto S. Elevated platelet activation in patients with atopic dermatitis and psoriasis: increased plasma levels of beta-thromboglobulin and platelet factor 4. Allergol Int. 2008;57:391-396.
    • (2008) Allergol Int , vol.57 , pp. 391-396
    • Tamagawa-Mineoka, R.1    Katoh, N.2    Ueda, E.3    Masuda, K.4    Kishimoto, S.5
  • 53
    • 0032944476 scopus 로고    scopus 로고
    • Significantly elevated expression of PF4 (platelet factor 4) and eotaxin in the NOA mouse, a model for atopic dermatitis
    • Watanabe O, Natori K, Tamari M, Shiomoto Y, Kubo S, Nakamura Y. Significantly elevated expression of PF4 (platelet factor 4) and eotaxin in the NOA mouse, a model for atopic dermatitis. J Hum Genet. 1999;44: 173-176.
    • (1999) J Hum Genet , vol.44 , pp. 173-176
    • Watanabe, O.1    Natori, K.2    Tamari, M.3    Shiomoto, Y.4    Kubo, S.5    Nakamura, Y.6
  • 54
    • 34548008184 scopus 로고    scopus 로고
    • Platelet factor 4 is a negative autocrine in vivo regulator of megakaryopoiesis: Clinical and therapeutic implications
    • Lambert MP, Rauova L, Bailey M, Sola-Visner MC, Kowalska MA, Poncz M. Platelet factor 4 is a negative autocrine in vivo regulator of megakaryopoiesis: clinical and therapeutic implications. Blood. 2007; 110:1153-1160.
    • (2007) Blood , vol.110 , pp. 1153-1160
    • Lambert, M.P.1    Rauova, L.2    Bailey, M.3    Sola-Visner, M.C.4    Kowalska, M.A.5    Poncz, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.