Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults

Haematologica

Volumn 95, Issue 1, 2010, Pages 79-86

  Gorello, Paolo ^a   La Starza, Roberta ^a   Varasano, Emanuela ^a   Chiaretti, Sabina ^b   Elia, Loredana ^b   Pierini, Valentina ^a   Barba, Gianluca ^a   Brandimarte, Lucia ^a   Crescenzi, Barbara ^a   Vitale, Antonella ^b   Messina, Monica ^b   Grammatico, Sara ^b   Mancini, Marco ^b   Matteucci, Caterina ^a   Bardi, Antonella ^c   Guarini, Anna ^b   Martelli, Massimo Fabrizio ^a   Foà, Robin ^b   Mecucci, Cristina ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF FERRARA   (Italy)

Author keywords

CI FISH; Genomic rearrangements; T ALL

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; MIXED LINEAGE LEUKEMIA PROTEIN; NOTCH1 RECEPTOR; NUCLEOPORIN 98; PROTEIN KINASE LCK; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; TRANSCRIPTION FACTOR ETV6; TRANSCRIPTION FACTOR HOXA10; TRANSCRIPTION FACTOR TAL1;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; CYTOGENETICS; DNA FINGERPRINTING; DOWN REGULATION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE ACTIVATION; GENE DELETION; GENE DUPLICATION; GENE EXPRESSION; GENE FUSION; GENE REARRANGEMENT; GENE TRANSLOCATION; GENETIC HETEROGENEITY; GENOMIC INSTABILITY; HUMAN; IMMUNOPHENOTYPING; KARYOTYPING; LEUKEMOGENESIS; MALE; MOLECULAR DYNAMICS; MULTIPLEX POLYMERASE CHAIN REACTION; ONCOGENE; ONCOGENE C MYB; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T CELL LEUKEMIA; TUMOR SUPPRESSOR GENE; UPREGULATION;

ADOLESCENT; ADULT; AGE FACTORS; COMPARATIVE GENOMIC HYBRIDIZATION; FEMALE; GENE EXPRESSION PROFILING; GENETIC HETEROGENEITY; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA-LYMPHOMA, ADULT T-CELL; MALE; MIDDLE AGED; MUTATION; YOUNG ADULT;

EID: 73949142365     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2009.010413     Document Type: Article

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