Mesenchymal stem cells cultured under hypoxia escape from senescence via down-regulation of p16 and extracellular signal regulated kinase

Biochemical and Biophysical Research Communications

Volumn 391, Issue 3, 2010, Pages 1471-1476

  Jin, Yonghui ^a   Kato, Tomohisa ^a   Furu, Moritoshi ^a   Nasu, Akira ^a,b   Kajita, Yoichiro ^a,b   Mitsui, Hiroto ^a,c   Ueda, Michiko ^a   Aoyama, Tomoki ^b   Nakayama, Tomitaka ^b   Nakamura, Takashi ^b   Toguchida, Junya ^a,b,d  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

Extracellular signal regulated kinase; Hypoxia; Mesenchymal stem cell; p16; Senescence

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P16;

ADIPOCYTE; ARTICLE; CARTILAGE CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HYPOXIA; MESENCHYME CELL; OSTEOCYTE; PRIORITY JOURNAL; SENESCENCE; SIGNAL TRANSDUCTION; UPREGULATION;

ANAEROBIOSIS; CELL AGING; CELL CULTURE TECHNIQUES; CELL HYPOXIA; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DOWN-REGULATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HUMANS; MESENCHYMAL STEM CELLS;

EID: 73949134198     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.12.096     Document Type: Article

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