An agonistic mAb directed to the TrkC receptor juxtamembrane region defines a trophic hot spot and interactions with p75 coreceptors

Developmental Neurobiology

Volumn 70, Issue 3, 2010, Pages 150-164

  Guillemard, Veronique ^a   Ivanisevic, Ljubica ^a   Garcia, Alba Galan ^a   Scholten, Vicki ^a   Lazo, Oscar M ^b   Bronfman, Francisca C ^b   Saragovi, H Uri ^a  

^a MCGILL UNIVERSITY   (Canada)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Agonist; Antibody; Ligand; NT 3; P75; Receptor; TrkC

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2B7; NEUROTROPHIN 3; NEUROTROPHIN RECEPTOR P75; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MEMBRANE; CELL SURFACE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ANIMALS; ANTIBODIES, MONOCLONAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HIPPOCAMPUS; HUMANS; MICE; NERVE GROWTH FACTORS; NEURONS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTOR, TRKC; RECEPTORS, NERVE GROWTH FACTOR;

EID: 73949119705     PISSN: 19328451     EISSN: 10974695     Source Type: Journal    
DOI: 10.1002/dneu.20776     Document Type: Article

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