Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 24, Issue 6, 2009, Pages 1269-1275

  Jaudzems, Kristaps ^a,b   Kuka, Janis ^a,c   Gutsaits, Aleksandrs ^a   Zinovjevs, Kirils ^a,b   Kalvinsh, Ivars ^a   Liepinsh, Edgars ^a   Liepinsh, Edvards ^a   Dambrova, Maija ^a  

^a LATVIAN INSTITUTE OF ORGANIC SYNTHESIS   (Latvia)

^b RIGA TECHNICAL UNIVERSITY   (Latvia)

^c RIGA STRADINS UNIVERSITY   (Latvia)

Author keywords

Acetyl CoA; Carnitine acetyltransferase; Inhibition; Mildronate; STD NMR

Indexed keywords

ACETYL COENZYME A; CARNITINE; CARNITINE ACETYLTRANSFERASE; MILDRONATE; TRIMETHYLAMMONIUM SALT DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL ANALYSIS; CONFORMATION; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG INHIBITION; DRUG POTENCY; ENERGY METABOLISM; ENZYME INHIBITION; ENZYME METABOLISM; ENZYME REGULATION; HEART PROTECTION; MOLECULAR DOCKING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PIGEON; PRIORITY JOURNAL; SATURATION TRANSFER DIFFERENCE SPECTROSCOPY; SPECTROSCOPY;

ANIMALS; BINDING SITES; BIOCATALYSIS; CARDIOVASCULAR AGENTS; CARNITINE O-ACETYLTRANSFERASE; COLUMBIDAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; ENZYME INHIBITORS; MAGNETIC RESONANCE SPECTROSCOPY; METHYLHYDRAZINES; MOLECULAR DYNAMICS SIMULATION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 73949103710     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756360902829527     Document Type: Article

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