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Volumn 289, Issue 1, 1999, Pages 93-102

Pharmacokinetic analysis of the cardioprotective effect of 3-(2,2,2- trimethylhydrazinium) propionate in mice: Inhibition of carnitine transport in kidney

Author keywords

[No Author keywords available]

Indexed keywords

CARNITINE; MILDRONATE;

EID: 0032940435     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (35)

References (35)
  • 2
    • 0030753860 scopus 로고    scopus 로고
    • Effect of MET-88, a γ-butyrobetaine hydroxylase inhibitor, on myocardial derangements induced by hydrogen peroxide in the isolated perfused rat heart
    • Akahira M, Hara A and Abiko Y (1997) Effect of MET-88, a γ-butyrobetaine hydroxylase inhibitor, on myocardial derangements induced by hydrogen peroxide in the isolated perfused rat heart. Fundam Clin Pharmacol 11:356-364.
    • (1997) Fundam Clin Pharmacol , vol.11 , pp. 356-364
    • Akahira, M.1    Hara, A.2    Abiko, Y.3
  • 5
    • 0019430908 scopus 로고
    • Carnitine transport in isolated adult rat heart myocytes and the effect of 7,8-di OH chlorpromazine
    • Bahl J, Navin T, Manian AA and Bressler R (1981) Carnitine transport in isolated adult rat heart myocytes and the effect of 7,8-di OH chlorpromazine. Circ Res 48:378-385.
    • (1981) Circ Res , vol.48 , pp. 378-385
    • Bahl, J.1    Navin, T.2    Manian, A.A.3    Bressler, R.4
  • 6
    • 0021008492 scopus 로고
    • Carnitine
    • Borum PR (1983) Carnitine. Annu Rev Nutr 3:233-259.
    • (1983) Annu Rev Nutr , vol.3 , pp. 233-259
    • Borum, P.R.1
  • 7
    • 0021024932 scopus 로고
    • Carnitine - Metabolism and functions
    • Bremer J (1983) Carnitine - metabolism and functions. Physiol Rev 63:1420-1480.
    • (1983) Physiol Rev , vol.63 , pp. 1420-1480
    • Bremer, J.1
  • 8
    • 0017106006 scopus 로고
    • Active transport of butyrobetaine and carnitine into isolated liver cells
    • Christiansen RZ and Bremer J (1976) Active transport of butyrobetaine and carnitine into isolated liver cells. Biochim Biophys Acta 448:562-577.
    • (1976) Biochim Biophys Acta , vol.448 , pp. 562-577
    • Christiansen, R.Z.1    Bremer, J.2
  • 9
    • 0021209872 scopus 로고
    • Amphipathic metabolites and membrane dysfunction in ischemic myocardium
    • Corr PB, Gross RW and Sobel BE (1984) Amphipathic metabolites and membrane dysfunction in ischemic myocardium. Circ Res 55:135-154.
    • (1984) Circ Res , vol.55 , pp. 135-154
    • Corr, P.B.1    Gross, R.W.2    Sobel, B.E.3
  • 10
    • 0026486495 scopus 로고
    • Paradoxical role of lipid metabolism in heart function and dysfunction
    • Dhalla NS, Elimban V and Rupp H (1992) Paradoxical role of lipid metabolism in heart function and dysfunction. Mol Cell Biochem 116:3-9.
    • (1992) Mol Cell Biochem , vol.116 , pp. 3-9
    • Dhalla, N.S.1    Elimban, V.2    Rupp, H.3
  • 11
    • 0000707075 scopus 로고    scopus 로고
    • Reduction of carnitine content by inhibition of its biosynthesis results in protection of isolated guinea pig hearts against hypoxic damage
    • Dhar PK, Grupp IL, Schwartz A, Grupp G and Matlib MA (1996) Reduction of carnitine content by inhibition of its biosynthesis results in protection of isolated guinea pig hearts against hypoxic damage. J Cardiovasc Pharmacol Therapeut 1:235-242.
    • (1996) J Cardiovasc Pharmacol Therapeut , vol.1 , pp. 235-242
    • Dhar, P.K.1    Grupp, I.L.2    Schwartz, A.3    Grupp, G.4    Matlib, M.A.5
  • 12
    • 0030925428 scopus 로고    scopus 로고
    • Excretion and metabolism of propionyl-L-carnitine in the isolated perfused rat kidney
    • Evans AM, Mancinelli A and Longo A (1997) Excretion and metabolism of propionyl-L-carnitine in the isolated perfused rat kidney. J Pharmacol Exp Ther 281:1071-1076.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 1071-1076
    • Evans, A.M.1    Mancinelli, A.2    Longo, A.3
  • 14
    • 0019156822 scopus 로고
    • Properties of carnitine transport in rat kidney cortex slices
    • Huth PJ and Shug AL (1980) Properties of carnitine transport in rat kidney cortex slices. Biochim Biophys Acta 602:621-634.
    • (1980) Biochim Biophys Acta , vol.602 , pp. 621-634
    • Huth, P.J.1    Shug, A.L.2
  • 16
    • 0020352452 scopus 로고
    • Selective killing of fibroblast-like cells in cultures of mouse heart cells by treatment with a Ca ionophore, A23187
    • Kaneko H and Goshima K (1982) Selective killing of fibroblast-like cells in cultures of mouse heart cells by treatment with a Ca ionophore, A23187. Exp Cell Res 142:407-416.
    • (1982) Exp Cell Res , vol.142 , pp. 407-416
    • Kaneko, H.1    Goshima, K.2
  • 17
    • 0029836940 scopus 로고    scopus 로고
    • Beneficial effect of MET-88, a γ-butyrobetaine hydroxylase inhibitor, on energy metabolism in ischemic dog hearts
    • Kirimoto T, Nobori K, Asaka N, Muranaka Y, Tajima K and Miyake H (1996) Beneficial effect of MET-88, a γ-butyrobetaine hydroxylase inhibitor, on energy metabolism in ischemic dog hearts. Arch Int Pharmacodyn Thèr 331:163-178.
    • (1996) Arch Int Pharmacodyn Thèr , vol.331 , pp. 163-178
    • Kirimoto, T.1    Nobori, K.2    Asaka, N.3    Muranaka, Y.4    Tajima, K.5    Miyake, H.6
  • 21
    • 0024262853 scopus 로고
    • Etomoxir, a carnitine palmitoyltransferase I inhibitor, protects hearts from fatty acid - Induced ischemic injury independent of changes in long chain acylcarnitine
    • Lopaschuk GD, Wall SR, Olley PM and Davies NJ (1988) Etomoxir, a carnitine palmitoyltransferase I inhibitor, protects hearts from fatty acid - induced ischemic injury independent of changes in long chain acylcarnitine. Circ Res 63:1036-1043.
    • (1988) Circ Res , vol.63 , pp. 1036-1043
    • Lopaschuk, G.D.1    Wall, S.R.2    Olley, P.M.3    Davies, N.J.4
  • 22
    • 0028982336 scopus 로고
    • Disposition of L-carnitine and acetyl-L-carnitine in the isolated perfused rat kidney
    • Mancinelli A, Longo A, Shanahan K and Evans AM (1995) Disposition of L-carnitine and acetyl-L-carnitine in the isolated perfused rat kidney. J Pharmacol Exp Ther 274:1122-1128.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 1122-1128
    • Mancinelli, A.1    Longo, A.2    Shanahan, K.3    Evans, A.M.4
  • 23
    • 0000163527 scopus 로고
    • Free and esterified carnitine. Radiometric method
    • (Bergmeyer HU ed) Academic Press, New York
    • McGarry JD and Foster DW (1985) Free and esterified carnitine. Radiometric method, in Methods of Enzymatic Analysis (Bergmeyer HU ed) pp 474-481, Academic Press, New York.
    • (1985) Methods of Enzymatic Analysis , pp. 474-481
    • McGarry, J.D.1    Foster, D.W.2
  • 24
    • 0020624753 scopus 로고
    • Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues
    • McGarry JD, Mills SE, Long CS and Foster DW (1983) Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Biochem J 214:21-28.
    • (1983) Biochem J , vol.214 , pp. 21-28
    • McGarry, J.D.1    Mills, S.E.2    Long, C.S.3    Foster, D.W.4
  • 26
    • 0030861585 scopus 로고    scopus 로고
    • Heterogeneity of histopathologic features in the congenitally carnitine-deficient juvenile visceral steatosis (JVS) mouse
    • Narama I, Ozaki K, Matsuura T, Ono A, Sei M, Shima K and Kuwajima M (1997) Heterogeneity of histopathologic features in the congenitally carnitine-deficient juvenile visceral steatosis (JVS) mouse. Biomed Res 18:247-255.
    • (1997) Biomed Res , vol.18 , pp. 247-255
    • Narama, I.1    Ozaki, K.2    Matsuura, T.3    Ono, A.4    Sei, M.5    Shima, K.6    Kuwajima, M.7
  • 27
    • 0021743458 scopus 로고
    • Sodium gradient-stimulated transport of L-carnitine into renal brush border membrane vesicles: Kinetics, specificity, and regulation by dietary carnitine
    • Rebouche CJ and Mack DL (1984) Sodium gradient-stimulated transport of L-carnitine into renal brush border membrane vesicles: Kinetics, specificity, and regulation by dietary carnitine. Arch Biochem Biophys 235:393-402.
    • (1984) Arch Biochem Biophys , vol.235 , pp. 393-402
    • Rebouche, C.J.1    Mack, D.L.2
  • 28
    • 0020713762 scopus 로고
    • Hypertaurinuria in the C57BL/6J mouse: Altered transport at the renal basolateral membrane
    • Rozen R, Scriver CR and Mohyuddin F (1983) Hypertaurinuria in the C57BL/6J mouse: Altered transport at the renal basolateral membrane. Am J Physiol 244: F150-F155.
    • (1983) Am J Physiol , vol.244
    • Rozen, R.1    Scriver, C.R.2    Mohyuddin, F.3
  • 29
    • 0027375181 scopus 로고
    • HPLC analysis of mildronate and its analogues in plasma
    • Sahartova O, Shatz V and Kalvins I (1993) HPLC analysis of mildronate and its analogues in plasma. J Pharm Biomed Anal 11:1045-1047.
    • (1993) J Pharm Biomed Anal , vol.11 , pp. 1045-1047
    • Sahartova, O.1    Shatz, V.2    Kalvins, I.3
  • 31
    • 0029030612 scopus 로고
    • Characterization of L-carnitine transport by rat kidney brush-border-membrane vesicles
    • Stieger B, O'Neill B and Krähenbühl S (1995) Characterization of L-carnitine transport by rat kidney brush-border-membrane vesicles. Biochem J 309:643-647.
    • (1995) Biochem J , vol.309 , pp. 643-647
    • Stieger, B.1    O'Neill, B.2    Krähenbühl, S.3
  • 33
    • 0031051909 scopus 로고    scopus 로고
    • Immune modulation with interleukin-4 and interleukin-10 prevents crescent formation and glomerular injury in experimental glomerulonephritis
    • Tipping PG, Kitching AR, Huang XR, Mutch DA and Holdsworth SR (1997) Immune modulation with interleukin-4 and interleukin-10 prevents crescent formation and glomerular injury in experimental glomerulonephritis. Eur J Immunol 27:530-537.
    • (1997) Eur J Immunol , vol.27 , pp. 530-537
    • Tipping, P.G.1    Kitching, A.R.2    Huang, X.R.3    Mutch, D.A.4    Holdsworth, S.R.5
  • 34
    • 0023655368 scopus 로고
    • Characterization of the mitochondrial carnitine palmitoyltransferase enzyme system. II. Use of detergents andantibodies
    • Woeltje KF, Kuwajima M, Foster DW and McGarry JD (1987) Characterization of the mitochondrial carnitine palmitoyltransferase enzyme system. II. Use of detergents andantibodies. J Biol Chem 262:9822-9827.
    • (1987) J Biol Chem , vol.262 , pp. 9822-9827
    • Woeltje, K.F.1    Kuwajima, M.2    Foster, D.W.3    McGarry, J.D.4
  • 35
    • 0019854279 scopus 로고
    • A pharmacokinetic analysis program (MULTI) for microcomputer
    • Yamaoka K, Tanigawara Y, Nakagawa T and Uno T (1981) A pharmacokinetic analysis program (MULTI) for microcomputer. J Pharm Dyn 4:879-885.
    • (1981) J Pharm Dyn , vol.4 , pp. 879-885
    • Yamaoka, K.1    Tanigawara, Y.2    Nakagawa, T.3    Uno, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.