-
1
-
-
0036212973
-
Aberrant splicing and premature termination of transcription of the FVIII gene as a cause of severe canine hemophilia A: similarities with the intron 22 inversion mutation in human hemophilia
-
Hough C, Kamisue S, Cameron C. Aberrant splicing and premature termination of transcription of the FVIII gene as a cause of severe canine hemophilia A: similarities with the intron 22 inversion mutation in human hemophilia. Thromb Haemost 2002, 87:659-65.
-
(2002)
Thromb Haemost
, vol.87
, pp. 659-665
-
-
Hough, C.1
Kamisue, S.2
Cameron, C.3
-
2
-
-
0032958510
-
A review of canine inherited bleeding disorders: biochemical and molecular strategies for disease characterization and carrier detection
-
Brooks M. A review of canine inherited bleeding disorders: biochemical and molecular strategies for disease characterization and carrier detection. J Hered 1999, 90:112-8.
-
(1999)
J Hered
, vol.90
, pp. 112-118
-
-
Brooks, M.1
-
3
-
-
0016008127
-
Hereditary and acquired hemorrhagic disorders in animals
-
Dodds WJ. Hereditary and acquired hemorrhagic disorders in animals. Prog Hemost Thromb 1974, 2:215-47.
-
(1974)
Prog Hemost Thromb
, vol.2
, pp. 215-247
-
-
Dodds, W.J.1
-
4
-
-
17344379296
-
Induction of acquired factor IX inhibitors in cynomolgus monkey (Macaca fascicularis): a new primate model of hemophilia B
-
Tomokiyo K, Teshima K, Nakatomi Y. Induction of acquired factor IX inhibitors in cynomolgus monkey (Macaca fascicularis): a new primate model of hemophilia B. Thromb Res 2001, 102:363-74.
-
(2001)
Thromb Res
, vol.102
, pp. 363-374
-
-
Tomokiyo, K.1
Teshima, K.2
Nakatomi, Y.3
-
5
-
-
0029073453
-
Blocking of tissue factor pathway inhibitor (TFPI) shortens the bleeding time in rabbits with antibody induced haemophilia A
-
Erhardtsen E, Ezban M, Madsen MT. Blocking of tissue factor pathway inhibitor (TFPI) shortens the bleeding time in rabbits with antibody induced haemophilia A. Blood Coagul Fibrinolysis 1995, 6:388-94.
-
(1995)
Blood Coagul Fibrinolysis
, vol.6
, pp. 388-394
-
-
Erhardtsen, E.1
Ezban, M.2
Madsen, M.T.3
-
6
-
-
0242494903
-
Improved hemostasis with superactive analogs of factor VIIa in a mouse model of hemophilia A
-
Tranholm M, Kristensen K, Kristensen AT, Pyke C, Rojkjaer R, Persson E. Improved hemostasis with superactive analogs of factor VIIa in a mouse model of hemophilia A. Blood 2003, 102:3615-20.
-
(2003)
Blood
, vol.102
, pp. 3615-3620
-
-
Tranholm, M.1
Kristensen, K.2
Kristensen, A.T.3
Pyke, C.4
Rojkjaer, R.5
Persson, E.6
-
7
-
-
0030817391
-
A coagulation factor IX-deficient mouse model for human hemophilia B
-
Lin HF, Maeda N, Smithies O, Straight DL, Stafford DW. A coagulation factor IX-deficient mouse model for human hemophilia B. Blood 1997, 90:3962-6.
-
(1997)
Blood
, vol.90
, pp. 3962-3966
-
-
Lin, H.F.1
Maeda, N.2
Smithies, O.3
Straight, D.L.4
Stafford, D.W.5
-
8
-
-
0029011723
-
Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A
-
Bi L, Lawler AM, Antonarakis SE, High KA, Gearhart JD, Kazazian HH. Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A. Nat Genet 1995, 10:119-21.
-
(1995)
Nat Genet
, vol.10
, pp. 119-121
-
-
Bi, L.1
Lawler, A.M.2
Antonarakis, S.E.3
High, K.A.4
Gearhart, J.D.5
Kazazian, H.H.6
-
9
-
-
0019812920
-
Hemophilic dog model for evaluating therapeutic effectiveness of plasma protein fractions
-
Kingdon HS, Hassell TM. Hemophilic dog model for evaluating therapeutic effectiveness of plasma protein fractions. Blood 1981, 58:868-72.
-
(1981)
Blood
, vol.58
, pp. 868-872
-
-
Kingdon, H.S.1
Hassell, T.M.2
-
10
-
-
0019973659
-
A canine model of hemophilic (factor VIII:C deficiency) bleeding
-
Giles AR, Tinlin S, Greenwood R. A canine model of hemophilic (factor VIII:C deficiency) bleeding. Blood 1982, 60:727-30.
-
(1982)
Blood
, vol.60
, pp. 727-730
-
-
Giles, A.R.1
Tinlin, S.2
Greenwood, R.3
-
11
-
-
0242398750
-
Recombinant human FVIIa dose dependeltly shortens the bleeding time in a rabbit model of antibody induced hamophilia A
-
Kristensen AT, Madsen MT, Nielsen GN, Ezban M. Recombinant human FVIIa dose dependeltly shortens the bleeding time in a rabbit model of antibody induced hamophilia A. Thromb Haemost 1999, 82:1038.
-
(1999)
Thromb Haemost
, vol.82
, pp. 1038
-
-
Kristensen, A.T.1
Madsen, M.T.2
Nielsen, G.N.3
Ezban, M.4
-
12
-
-
0023741490
-
In vivo characterization of recombinant factor VIII in a canine model of hemophilia A (factor VIII deficiency)
-
Giles AR, Tinlin S, Hoogendoorn H, Fournel MA, Ng P, Pancham N. In vivo characterization of recombinant factor VIII in a canine model of hemophilia A (factor VIII deficiency). Blood 1988, 72:335-9.
-
(1988)
Blood
, vol.72
, pp. 335-339
-
-
Giles, A.R.1
Tinlin, S.2
Hoogendoorn, H.3
Fournel, M.A.4
Ng, P.5
Pancham, N.6
-
13
-
-
0025614949
-
A simple method to create carotid endothelial laceration and acute platelet thrombus in vivo in guinea-pig
-
Huang ZS, Lee TK, Teng CM, Wang CY, Huang LH, Chang CH. A simple method to create carotid endothelial laceration and acute platelet thrombus in vivo in guinea-pig. Thromb Res 1990, 60:109-19.
-
(1990)
Thromb Res
, vol.60
, pp. 109-119
-
-
Huang, Z.S.1
Lee, T.K.2
Teng, C.M.3
Wang, C.Y.4
Huang, L.H.5
Chang, C.H.6
-
14
-
-
0034650976
-
Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice
-
Eitzman DT, Westrick RJ, Nabel EG, Ginsburg D. Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice. Blood 2000, 95:577-80.
-
(2000)
Blood
, vol.95
, pp. 577-580
-
-
Eitzman, D.T.1
Westrick, R.J.2
Nabel, E.G.3
Ginsburg, D.4
-
15
-
-
0036799775
-
Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse
-
Falati S, Gross P, Merrill-Skoloff G, Furie BC, Furie B. Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse. Nat Med 2002, 8:1175-81.
-
(2002)
Nat Med
, vol.8
, pp. 1175-1181
-
-
Falati, S.1
Gross, P.2
Merrill-Skoloff, G.3
Furie, B.C.4
Furie, B.5
-
16
-
-
35648971614
-
Electric injury model of murine arterial thrombosis
-
Kusada A, Isogai N, Cooley BC. Electric injury model of murine arterial thrombosis. Thromb Res 2007, 121:103-6.
-
(2007)
Thromb Res
, vol.121
, pp. 103-106
-
-
Kusada, A.1
Isogai, N.2
Cooley, B.C.3
-
17
-
-
0025614358
-
Rat model of arterial thrombosis induced by ferric chloride
-
Kurz KD, Main BW, Sandusky GE. Rat model of arterial thrombosis induced by ferric chloride. Thromb Res 1990, 60:269-80.
-
(1990)
Thromb Res
, vol.60
, pp. 269-280
-
-
Kurz, K.D.1
Main, B.W.2
Sandusky, G.E.3
-
18
-
-
0033135457
-
Antithrombotic effects and bleeding time of thrombin inhibitors and warfarin in the rat
-
Elg M, Gustafsson D, Carlsson S. Antithrombotic effects and bleeding time of thrombin inhibitors and warfarin in the rat. Thromb Res 1999, 94:187-97.
-
(1999)
Thromb Res
, vol.94
, pp. 187-197
-
-
Elg, M.1
Gustafsson, D.2
Carlsson, S.3
-
19
-
-
33746234764
-
Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets
-
Schwarz M, Meade G, Stoll P. Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets. Circ Res 2006, 99:25-33.
-
(2006)
Circ Res
, vol.99
, pp. 25-33
-
-
Schwarz, M.1
Meade, G.2
Stoll, P.3
-
20
-
-
10444238012
-
Combined effects of a factor Xa inhibitor YM466 and a GPIIb/IIIa antagonist YM128 on thrombosis and neointima formation in mice
-
Iwatsuki Y, Kawasaki T, Hayashi K, Moritani Y, Nii T, Miyata K. Combined effects of a factor Xa inhibitor YM466 and a GPIIb/IIIa antagonist YM128 on thrombosis and neointima formation in mice. Thromb Haemost 2004, 92:1221-8.
-
(2004)
Thromb Haemost
, vol.92
, pp. 1221-1228
-
-
Iwatsuki, Y.1
Kawasaki, T.2
Hayashi, K.3
Moritani, Y.4
Nii, T.5
Miyata, K.6
-
21
-
-
0033659684
-
TPA, but not uPA, significantly affects antithrombotic therapy by a glycoprotein IIb/IIIa antagonist, but not by a factor Xa inhibitor
-
Nishida M, Matsuno H, Kozawa O. tPA, but not uPA, significantly affects antithrombotic therapy by a glycoprotein IIb/IIIa antagonist, but not by a factor Xa inhibitor. J Cardiovasc Pharmacol 2000, 36:770-5.
-
(2000)
J Cardiovasc Pharmacol
, vol.36
, pp. 770-775
-
-
Nishida, M.1
Matsuno, H.2
Kozawa, O.3
-
22
-
-
23044488487
-
Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4′,4′',4′''-(carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis -benzene-1,3-disulfonic acid octasodium salt]
-
Hechler B, Magnenat S, Zighetti ML. Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4′,4′',4′''-(carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis -benzene-1,3-disulfonic acid octasodium salt]. J Pharmacol Exp Ther 2005, 314:232-43.
-
(2005)
J Pharmacol Exp Ther
, vol.314
, pp. 232-243
-
-
Hechler, B.1
Magnenat, S.2
Zighetti, M.L.3
-
23
-
-
33748602905
-
Antithrombin is as effective as heparin and hirudin to prevent formation of microvascular thrombosis in a murine model
-
Sorg H, Hoffmann JN, Menger MD, Lindenblatt N, Goehring P, Vollmar B. Antithrombin is as effective as heparin and hirudin to prevent formation of microvascular thrombosis in a murine model. Thromb Haemost 2006, 96:371-7.
-
(2006)
Thromb Haemost
, vol.96
, pp. 371-377
-
-
Sorg, H.1
Hoffmann, J.N.2
Menger, M.D.3
Lindenblatt, N.4
Goehring, P.5
Vollmar, B.6
-
24
-
-
0034681376
-
Antithrombotic efficacy of RPR208566, a novel factor Xa inhibitor, in a rat model of carotid artery thrombosis
-
Heran C, Morgan S, Kasiewski C. Antithrombotic efficacy of RPR208566, a novel factor Xa inhibitor, in a rat model of carotid artery thrombosis. Eur J Pharmacol 2000, 389:201-7.
-
(2000)
Eur J Pharmacol
, vol.389
, pp. 201-207
-
-
Heran, C.1
Morgan, S.2
Kasiewski, C.3
-
25
-
-
0033838314
-
Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen
-
Ni H, Denis CV, Subbarao S. Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest 2000, 106:385-92.
-
(2000)
J Clin Invest
, vol.106
, pp. 385-392
-
-
Ni, H.1
Denis, C.V.2
Subbarao, S.3
-
26
-
-
12444303861
-
Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin
-
Falati S, Liu Q, Gross P. Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin. J Exp Med 2003, 197:1585-98.
-
(2003)
J Exp Med
, vol.197
, pp. 1585-1598
-
-
Falati, S.1
Liu, Q.2
Gross, P.3
-
27
-
-
0033559292
-
Vitronectin inhibits the thrombotic response to arterial injury in mice
-
Fay WP, Parker AC, Ansari MN, Zheng X, Ginsburg D. Vitronectin inhibits the thrombotic response to arterial injury in mice. Blood 1999, 93:1825-30.
-
(1999)
Blood
, vol.93
, pp. 1825-1830
-
-
Fay, W.P.1
Parker, A.C.2
Ansari, M.N.3
Zheng, X.4
Ginsburg, D.5
-
28
-
-
43749094984
-
Hemostatic effect of recombinant factor VIIa, NN1731 and recombinant factor VIII on needle-induced joint bleeding in hemophilia A mice
-
Ovlisen K, Kristensen AT, Valentino LA, Hakobyan N, Ingerslev J, Tranholm M. Hemostatic effect of recombinant factor VIIa, NN1731 and recombinant factor VIII on needle-induced joint bleeding in hemophilia A mice. J Thromb Haemost 2008, 6:969-75.
-
(2008)
J Thromb Haemost
, vol.6
, pp. 969-975
-
-
Ovlisen, K.1
Kristensen, A.T.2
Valentino, L.A.3
Hakobyan, N.4
Ingerslev, J.5
Tranholm, M.6
-
29
-
-
2342538377
-
Experimental haemophilic synovitis: rationale and development of a murine model of human factor VIII deficiency
-
Valentino LA, Hakobyan N, Kazarian T, Jabbar KJ, Jabbar AA. Experimental haemophilic synovitis: rationale and development of a murine model of human factor VIII deficiency. Haemophilia 2004, 10:280-7.
-
(2004)
Haemophilia
, vol.10
, pp. 280-287
-
-
Valentino, L.A.1
Hakobyan, N.2
Kazarian, T.3
Jabbar, K.J.4
Jabbar, A.A.5
-
30
-
-
63049109313
-
Prevention of haemarthrosis in a murine model of acute joint bleeding
-
Valentino LA, Hakobyan N, Kazarian T, Sorensen BB, Tranholm M. Prevention of haemarthrosis in a murine model of acute joint bleeding. Haemophilia 2009, 15:314-9.
-
(2009)
Haemophilia
, vol.15
, pp. 314-319
-
-
Valentino, L.A.1
Hakobyan, N.2
Kazarian, T.3
Sorensen, B.B.4
Tranholm, M.5
-
31
-
-
73949100024
-
Histological characterization of mouse carotid artery alteration following ferric chloride-induced injury
-
Abstract OC-TH-035
-
Eckly A, Freund M, Zerr Fouineau M. Histological characterization of mouse carotid artery alteration following ferric chloride-induced injury. J Thromb Haemost 2009, 7:278. Abstract OC-TH-035
-
(2009)
J Thromb Haemost
, vol.7
, pp. 278
-
-
Eckly, A.1
Freund, M.2
Zerr Fouineau, M.3
-
32
-
-
73949096574
-
The effect of N8 and rFVIII on needle induced hemarthrosis in hemophilia a mice
-
Abstract PP-WE-581
-
Øvlisen K, Kjalke M, Tranholm M. The effect of N8 and rFVIII on needle induced hemarthrosis in hemophilia a mice. J Thromb Haemost 2009, 7:823. Abstract PP-WE-581
-
(2009)
J Thromb Haemost
, vol.7
, pp. 823
-
-
Øvlisen, K.1
Kjalke, M.2
Tranholm, M.3
-
33
-
-
29244443415
-
Factor V Leiden improves in vivo hemostasis in murine hemophilia models
-
Schlachterman A, Schuettrumpf J, Liu JH. Factor V Leiden improves in vivo hemostasis in murine hemophilia models. J Thromb Haemost 2005, 3:2730-7.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 2730-2737
-
-
Schlachterman, A.1
Schuettrumpf, J.2
Liu, J.H.3
-
34
-
-
45549109031
-
Platelet-delivered factor VIII provides limited resistance to anti-factor VIII inhibitors
-
Gewirtz J, Thornton MA, Rauova L, Poncz M. Platelet-delivered factor VIII provides limited resistance to anti-factor VIII inhibitors. J Thromb Haemost 2008, 6:1160-6.
-
(2008)
J Thromb Haemost
, vol.6
, pp. 1160-1166
-
-
Gewirtz, J.1
Thornton, M.A.2
Rauova, L.3
Poncz, M.4
-
35
-
-
10744231807
-
Factor VIII ectopically expressed in platelets: efficacy in hemophilia A treatment
-
Yarovoi HV, Kufrin D, Eslin DE. Factor VIII ectopically expressed in platelets: efficacy in hemophilia A treatment. Blood 2003, 102:4006-13.
-
(2003)
Blood
, vol.102
, pp. 4006-4013
-
-
Yarovoi, H.V.1
Kufrin, D.2
Eslin, D.E.3
-
36
-
-
33947204691
-
Von Willebrand factor and factor VIII are independently required to form stable occlusive thrombi in injured veins
-
Chauhan AK, Kisucka J, Lamb CB, Bergmeier W, Wagner DD. von Willebrand factor and factor VIII are independently required to form stable occlusive thrombi in injured veins. Blood 2007, 109:2424-9.
-
(2007)
Blood
, vol.109
, pp. 2424-2429
-
-
Chauhan, A.K.1
Kisucka, J.2
Lamb, C.B.3
Bergmeier, W.4
Wagner, D.D.5
-
37
-
-
43049115706
-
Long-term expression of murine activated factor VII is safe, but elevated levels cause premature mortality
-
Aljamali MN, Margaritis P, Schlachterman A. Long-term expression of murine activated factor VII is safe, but elevated levels cause premature mortality. J Clin Invest 2008, 118:1825-34.
-
(2008)
J Clin Invest
, vol.118
, pp. 1825-1834
-
-
Aljamali, M.N.1
Margaritis, P.2
Schlachterman, A.3
-
38
-
-
36248972253
-
In vivo response to vascular injury in the absence of factor IX: examination in factor IX knockout mice
-
Gui T, Reheman A, Funkhouser WK. In vivo response to vascular injury in the absence of factor IX: examination in factor IX knockout mice. Thromb Res 2007, 121:225-34.
-
(2007)
Thromb Res
, vol.121
, pp. 225-234
-
-
Gui, T.1
Reheman, A.2
Funkhouser, W.K.3
-
39
-
-
23044453832
-
Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice
-
Wang X, Cheng Q, Xu L. Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice. J Thromb Haemost 2005, 3:695-702.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 695-702
-
-
Wang, X.1
Cheng, Q.2
Xu, L.3
-
40
-
-
9644291604
-
An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research
-
Wang X, Xu L. An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research. Thromb Res 2005, 115:95-100.
-
(2005)
Thromb Res
, vol.115
, pp. 95-100
-
-
Wang, X.1
Xu, L.2
-
41
-
-
0035883064
-
Variable protection of beta 3-integrin-deficient mice from thrombosis initiated by different mechanisms
-
Smyth SS, Reis ED, Vaananen H, Zhang W, Coller BS. Variable protection of beta 3-integrin-deficient mice from thrombosis initiated by different mechanisms. Blood 2001, 98:1055-62.
-
(2001)
Blood
, vol.98
, pp. 1055-1062
-
-
Smyth, S.S.1
Reis, E.D.2
Vaananen, H.3
Zhang, W.4
Coller, B.S.5
-
42
-
-
0032483024
-
A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis
-
Denis C, Methia N, Frenette PS. A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proc Natl Acad Sci USA 1998, 95:9524-9.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9524-9529
-
-
Denis, C.1
Methia, N.2
Frenette, P.S.3
|