Combined effects of a factor Xa inhibitor YM466 and a GPIIb/IIIa antagonist YM128 on thrombosis and neointima formation in mice

Thrombosis and Haemostasis

Volumn 92, Issue 6, 2004, Pages 1221-1228

  Iwatsuki, Yoshiyuki ^a   Kawasaki, Tomihisa ^a   Hayashi, Kazumi ^a   Moritani, Yumiko ^a   Nii, Tomoko ^a   Miyata, Keiji ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Combination; Factor Xa inhibitor; GPllb llla antagonist; Neointima formation; Thrombosis

Indexed keywords

BLOOD CLOTTING FACTOR 10A INHIBITOR; BLOOD CLOTTING INHIBITOR; FERROUS CHLORIDE; FIBRINOGEN RECEPTOR ANTAGONIST; PROTHROMBIN; UNCLASSIFIED DRUG; YM 128; YM 466; YM 57029;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; BLEEDING TIME; CAROTID ARTERY INJURY; CAROTID ARTERY OBSTRUCTION; CAROTID ARTERY THROMBOSIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; HISTOPATHOLOGY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTHROMBIN TIME; THROMBOCYTE AGGREGATION INHIBITION; TRANSLUMINAL CORONARY ANGIOPLASTY;

ANGIOPLASTY; ANIMALS; BLEEDING TIME; BLOOD COAGULATION; BLOOD PLATELETS; CAROTID ARTERIES; CAROTID ARTERY THROMBOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FACTOR XA; FERRIC COMPOUNDS; MICE; MICE, INBRED ICR; NAPHTHALENES; PIPERAZINES; PIPERIDINES; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTHROMBIN TIME; THROMBOSIS; TIME FACTORS;

EID: 10444238012     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH04-04-0206     Document Type: Article

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