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Volumn 176, Issue 1, 2010, Pages 416-434

Mice lacking dystrophin or α sarcoglycan spontaneously develop embryonal rhabdomyosarcoma with cancer-associated p53 mutations and alternatively spliced or mutant Mdm2 transcripts

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DYSTROGLYCAN; ALPHA SARCOGLYCAN; DYSTROPHIN; MESSENGER RNA; MUTANT PROTEIN; PHOSPHATASE; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P53; RETINOBLASTOMA PROTEIN; SOMATOMEDIN B;

EID: 73949088241     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.090405     Document Type: Article
Times cited : (44)

References (104)
  • 2
    • 0030272647 scopus 로고    scopus 로고
    • Dystroglycan: An extracellular matrix receptor linked to the cytoskeleton
    • Henry MD, Campbell KP: Dystroglycan: an extracellular matrix receptor linked to the cytoskeleton. Curr Opin Cell Biol 1996, 8:625-631
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 625-631
    • Henry, M.D.1    Campbell, K.P.2
  • 3
    • 32244440192 scopus 로고    scopus 로고
    • Dystroglycan: From biosynthesis to pathogenesis of human disease
    • Barresi R, Campbell KP: Dystroglycan: from biosynthesis to pathogenesis of human disease. J Cell Sci 2006, 119:199-207
    • (2006) J Cell Sci , vol.119 , pp. 199-207
    • Barresi, R.1    Campbell, K.P.2
  • 4
    • 26444466088 scopus 로고    scopus 로고
    • The dystroglycan complex: From biology to cancer
    • Sgambato A, Brancaccio A: The dystroglycan complex: from biology to cancer. J Cell Physiol 2005, 205:163-169
    • (2005) J Cell Physiol , vol.205 , pp. 163-169
    • Sgambato, A.1    Brancaccio, A.2
  • 6
    • 33749462666 scopus 로고    scopus 로고
    • Rhabdomyosarcomas in adults and children: An update
    • Parham DM, Ellison DA: Rhabdomyosarcomas in adults and children: an update. Arch Pathol Lab Med 2006, 130:1454-1465
    • (2006) Arch Pathol Lab Med , vol.130 , pp. 1454-1465
    • Parham, D.M.1    Ellison, D.A.2
  • 7
    • 0036087342 scopus 로고    scopus 로고
    • Function and genetics of dystrophin and dystrophin-related proteins in muscle
    • Blake DJ, Weir A, Newey SE, Davies KE: Function and genetics of dystrophin and dystrophin-related proteins in muscle. Physiol Rev 2002, 82:291-329
    • (2002) Physiol Rev , vol.82 , pp. 291-329
    • Blake, D.J.1    Weir, A.2    Newey, S.E.3    Davies, K.E.4
  • 8
    • 0025815479 scopus 로고
    • Membrane organization of the dystrophinglycoprotein complex
    • Ervasti JM, Campbell KP: Membrane organization of the dystrophinglycoprotein complex. Cell 1991, 66:1121-1131
    • (1991) Cell , vol.66 , pp. 1121-1131
    • Ervasti, J.M.1    Campbell, K.P.2
  • 10
    • 0033186114 scopus 로고    scopus 로고
    • WW and EF hand domains of dystrophinfamily proteins mediate dystroglycan binding
    • Chung W, Campanelli JT: WW and EF hand domains of dystrophinfamily proteins mediate dystroglycan binding. Mol Cell Biol Res Commun 1999, 2:162-171
    • (1999) Mol Cell Biol Res Commun , vol.2 , pp. 162-171
    • Chung, W.1    Campanelli, J.T.2
  • 13
    • 24044447239 scopus 로고    scopus 로고
    • Evidence that dystroglycan is associated with dynamin and regulates endocytosis
    • Zhan Y, Tremblay MR, Melian N, Carbonetto S: Evidence that dystroglycan is associated with dynamin and regulates endocytosis. J Biol Chem 2005, 280:18015-18024
    • (2005) J Biol Chem , vol.280 , pp. 18015-18024
    • Zhan, Y.1    Tremblay, M.R.2    Melian, N.3    Carbonetto, S.4
  • 14
    • 2942604709 scopus 로고    scopus 로고
    • Dystroglycan, a scaffold for the ERK-MAP kinase cascade
    • Spence HJ, Dhillon AS, James M, Winder SJ: Dystroglycan, a scaffold for the ERK-MAP kinase cascade. EMBO Rep 2004, 5:484-489
    • (2004) EMBO Rep , vol.5 , pp. 484-489
    • Spence, H.J.1    Dhillon, A.S.2    James, M.3    Winder, S.J.4
  • 15
    • 0036842214 scopus 로고    scopus 로고
    • Inhibition of dystroglycan binding to laminin disrupts the PI3K/AKT pathway and survival signaling in muscle cells
    • Langenbach KJ, Rando TA: Inhibition of dystroglycan binding to laminin disrupts the PI3K/AKT pathway and survival signaling in muscle cells. Muscle Nerve 2002, 26:644-653
    • (2002) Muscle Nerve , vol.26 , pp. 644-653
    • Langenbach, K.J.1    Rando, T.A.2
  • 16
    • 0035807788 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of beta-dystroglycan at its WW domain binding motif. PPxY, recruits SH2 domain containing proteins
    • Sotgia F, Lee H, Bedford MT, Petrucci T, Sudol M, Lisanti MP: Tyrosine phosphorylation of beta-dystroglycan at its WW domain binding motif. PPxY, recruits SH2 domain containing proteins. Biochemistry 2001, 40:14585-14592
    • (2001) Biochemistry , vol.40 , pp. 14585-14592
    • Sotgia, F.1    Lee, H.2    Bedford, M.T.3    Petrucci, T.4    Sudol, M.5    Lisanti, M.P.6
  • 17
    • 0029155684 scopus 로고
    • Rapsyn may function as a link between the acetylcholine receptor and the agrin-binding dystrophin-associated glycoprotein complex
    • Apel ED, Roberds SL, Campbell KP, Merlie JP: Rapsyn may function as a link between the acetylcholine receptor and the agrin-binding dystrophin-associated glycoprotein complex. Neuron 1995, 15:115-126
    • (1995) Neuron , vol.15 , pp. 115-126
    • Apel, E.D.1    Roberds, S.L.2    Campbell, K.P.3    Merlie, J.P.4
  • 18
    • 0027275643 scopus 로고
    • A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin
    • Ervasti JM, Campbell KP: A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin. J Cell Biol 1993, 122:809-823
    • (1993) J Cell Biol , vol.122 , pp. 809-823
    • Ervasti, J.M.1    Campbell, K.P.2
  • 19
    • 0038182574 scopus 로고    scopus 로고
    • Dystrophin-glycoprotein complex: Posttranslational processing and dystroglycan function
    • Michele DE, Campbell KP: Dystrophin-glycoprotein complex: posttranslational processing and dystroglycan function. J Biol Chem 2003, 278:15457-15460
    • (2003) J Biol Chem , vol.278 , pp. 15457-15460
    • Michele, D.E.1    Campbell, K.P.2
  • 20
    • 0023614188 scopus 로고
    • Dystrophin: The protein product of the Duchenne muscular dystrophy locus
    • Hoffman EP, Brown RH Jr, Kunkel LM: Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 1987, 51:919-928
    • (1987) Cell , vol.51 , pp. 919-928
    • Hoffman, E.P.1    Brown Jr, R.H.2    Kunkel, L.M.3
  • 21
    • 0028318185 scopus 로고
    • Deficiency of merosin in dystrophic dy mice and genetic linkage of lamininMchain gene to dy locus
    • Sunada Y, Bernier SM, Kozak CA, Yamada Y, Campbell KP: Deficiency of merosin in dystrophic dy mice and genetic linkage of lamininMchain gene to dy locus. J Biol Chem 1994, 269:13729-13732
    • (1994) J Biol Chem , vol.269 , pp. 13729-13732
    • Sunada, Y.1    Bernier, S.M.2    Kozak, C.A.3    Yamada, Y.4    Campbell, K.P.5
  • 22
    • 0028334735 scopus 로고
    • Defective muscle basement membrane and lack of M-laminin in the dystrophic dy/dy mouse
    • Xu H, Christmas P, Wu XR, Wewer UM, Engvall E: Defective muscle basement membrane and lack of M-laminin in the dystrophic dy/dy mouse. Proc Natl Acad Sci USA 1994, 91:5572-5576
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5572-5576
    • Xu, H.1    Christmas, P.2    Wu, X.R.3    Wewer, U.M.4    Engvall, E.5
  • 25
    • 33645366723 scopus 로고    scopus 로고
    • Mechanisms of Disease: Congenital muscular dystrophies-glycosylation takes center stage
    • Martin PT: Mechanisms of Disease: congenital muscular dystrophies-glycosylation takes center stage. Nat Clin Pract Neurol 2006, 2:222-230
    • (2006) Nat Clin Pract Neurol , vol.2 , pp. 222-230
    • Martin, P.T.1
  • 27
    • 0034870766 scopus 로고    scopus 로고
    • Reduced expression of dystroglycan in breast and prostate cancer
    • Henry MD, Cohen MB, Campbell KP: Reduced expression of dystroglycan in breast and prostate cancer. Hum Pathol 2001, 32:791-795
    • (2001) Hum Pathol , vol.32 , pp. 791-795
    • Henry, M.D.1    Cohen, M.B.2    Campbell, K.P.3
  • 28
    • 0036894605 scopus 로고    scopus 로고
    • A role for dystroglycan in epithelial polarization: Loss of function in breast tumor cells
    • Muschler J, Levy D, Boudreau R, Henry M, Campbell K, Bissell MJ: A role for dystroglycan in epithelial polarization: loss of function in breast tumor cells. Cancer Res 2002, 62:7102-7109
    • (2002) Cancer Res , vol.62 , pp. 7102-7109
    • Muschler, J.1    Levy, D.2    Boudreau, R.3    Henry, M.4    Campbell, K.5    Bissell, M.J.6
  • 30
    • 4444228394 scopus 로고    scopus 로고
    • Aberrant expression, processing and degradation of dystroglycan in squamous cell carcinomas
    • Jing J, Lien CF, Sharma S, Rice J, Brennan PA, Gorecki DC: Aberrant expression, processing and degradation of dystroglycan in squamous cell carcinomas. Eur J Cancer 2004, 40:2143-2151
    • (2004) Eur J Cancer , vol.40 , pp. 2143-2151
    • Jing, J.1    Lien, C.F.2    Sharma, S.3    Rice, J.4    Brennan, P.A.5    Gorecki, D.C.6
  • 32
    • 35348891997 scopus 로고    scopus 로고
    • Altered expression of natively glycosylated alpha dystroglycan in pediatric solid tumors
    • Martin LT, Glass M, Dosunmu E, Martin PT: Altered expression of natively glycosylated alpha dystroglycan in pediatric solid tumors. Hum Pathol 2007, 38:1657-1668
    • (2007) Hum Pathol , vol.38 , pp. 1657-1668
    • Martin, L.T.1    Glass, M.2    Dosunmu, E.3    Martin, P.T.4
  • 36
    • 0026621608 scopus 로고
    • Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle
    • Matsumura K, Ervasti JM, Ohlendieck K, Kahl SD, Campbell KP: Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle. Nature 1992, 360:588-591
    • (1992) Nature , vol.360 , pp. 588-591
    • Matsumura, K.1    Ervasti, J.M.2    Ohlendieck, K.3    Kahl, S.D.4    Campbell, K.P.5
  • 38
    • 0344171979 scopus 로고    scopus 로고
    • Common musculoskeletal tumors of childhood and adolescence
    • Arndt CA, Crist WM: Common musculoskeletal tumors of childhood and adolescence. N Engl J Med 1999, 341:342-352
    • (1999) N Engl J Med , vol.341 , pp. 342-352
    • Arndt, C.A.1    Crist, W.M.2
  • 39
    • 33747588111 scopus 로고    scopus 로고
    • An immunohistochemical algorithm to facilitate diagnosis and subtyping of rhabdomyosarcoma: The Children's Oncology Group experience
    • Morotti RA, Nicol KK, Parham DM, Teot LA, Moore J, Hayes J, Meyer W, Qualman SJ: An immunohistochemical algorithm to facilitate diagnosis and subtyping of rhabdomyosarcoma: the Children's Oncology Group experience. Am J Surg Pathol 2006, 30:962-968
    • (2006) Am J Surg Pathol , vol.30 , pp. 962-968
    • Morotti, R.A.1    Nicol, K.K.2    Parham, D.M.3    Teot, L.A.4    Moore, J.5    Hayes, J.6    Meyer, W.7    Qualman, S.J.8
  • 40
    • 0035031713 scopus 로고    scopus 로고
    • Pathologic classification of rhabdomyosarcomas and correlations with molecular studies
    • Parham DM: Pathologic classification of rhabdomyosarcomas and correlations with molecular studies. Mod Pathol 2001, 14:506-514
    • (2001) Mod Pathol , vol.14 , pp. 506-514
    • Parham, D.M.1
  • 41
    • 0028364374 scopus 로고
    • Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma
    • Davis RJ, D'Cruz CM, Lovell MA, Biegel JA, Barr FG: Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res 1994, 54:2869-2872
    • (1994) Cancer Res , vol.54 , pp. 2869-2872
    • Davis, R.J.1    D'Cruz, C.M.2    Lovell, M.A.3    Biegel, J.A.4    Barr, F.G.5
  • 42
    • 0027534945 scopus 로고
    • Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma
    • Barr FG, Galili N, Holick J, Biegel JA, Rovera G, Emanuel BS: Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma. Nat Genet 1993, 3:113-117
    • (1993) Nat Genet , vol.3 , pp. 113-117
    • Barr, F.G.1    Galili, N.2    Holick, J.3    Biegel, J.A.4    Rovera, G.5    Emanuel, B.S.6
  • 43
    • 0035839886 scopus 로고    scopus 로고
    • Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma
    • Barr FG: Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma. Oncogene 2001, 20:5736-5746
    • (2001) Oncogene , vol.20 , pp. 5736-5746
    • Barr, F.G.1
  • 44
    • 0021932813 scopus 로고
    • Loss of heterozygosity in three embryonal tumours suggests a common pathogenetic mechanism
    • Koufos A, Hansen MF, Copeland NG, Jenkins NA, Lampkin BC, Cavenee WK: Loss of heterozygosity in three embryonal tumours suggests a common pathogenetic mechanism. Nature 1985, 316:330-334
    • (1985) Nature , vol.316 , pp. 330-334
    • Koufos, A.1    Hansen, M.F.2    Copeland, N.G.3    Jenkins, N.A.4    Lampkin, B.C.5    Cavenee, W.K.6
  • 45
    • 0033205985 scopus 로고    scopus 로고
    • Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma
    • Anderson J, Gordon A, McManus A, Shipley J, Pritchard-Jones K: Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma. Neoplasia 1999, 1:340-348
    • (1999) Neoplasia , vol.1 , pp. 340-348
    • Anderson, J.1    Gordon, A.2    McManus, A.3    Shipley, J.4    Pritchard-Jones, K.5
  • 47
    • 0014654544 scopus 로고
    • Rhabdomyosarcoma in children: Epidemiologic study and identification of a familial cancer syndrome
    • Li FP, Fraumeni JF Jr: Rhabdomyosarcoma in children: epidemiologic study and identification of a familial cancer syndrome. J Natl Cancer Inst 1969, 43:1365-1373
    • (1969) J Natl Cancer Inst , vol.43 , pp. 1365-1373
    • Li, F.P.1    Fraumeni Jr, J.F.2
  • 51
    • 2642528708 scopus 로고    scopus 로고
    • Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma
    • Takahashi Y, Oda Y, Kawaguchi K, Tamiya S, Yamamoto H, Suita S, Tsuneyoshi M: Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma. Mod Pathol 2004, 17:660-669
    • (2004) Mod Pathol , vol.17 , pp. 660-669
    • Takahashi, Y.1    Oda, Y.2    Kawaguchi, K.3    Tamiya, S.4    Yamamoto, H.5    Suita, S.6    Tsuneyoshi, M.7
  • 52
    • 7544243041 scopus 로고    scopus 로고
    • Alveolar rhabdomyosarcomas in conditional Pax3: Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function
    • Keller C, Arenkiel BR, Coffin CM, El-Bardeesy N, DePinho RA, Capecchi MR: Alveolar rhabdomyosarcomas in conditional Pax3: Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function. Genes Dev 2004, 18:2614-2626
    • (2004) Genes Dev , vol.18 , pp. 2614-2626
    • Keller, C.1    Arenkiel, B.R.2    Coffin, C.M.3    El-Bardeesy, N.4    DePinho, R.A.5    Capecchi, M.R.6
  • 56
    • 34548598298 scopus 로고    scopus 로고
    • PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound
    • Cen L, Hsieh FC, Lin HJ, Chen CS, Qualman SJ, Lin J: PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound. Br J Cancer 2007, 97:785-791
    • (2007) Br J Cancer , vol.97 , pp. 785-791
    • Cen, L.1    Hsieh, F.C.2    Lin, H.J.3    Chen, C.S.4    Qualman, S.J.5    Lin, J.6
  • 58
    • 0345687903 scopus 로고    scopus 로고
    • Levels of PTEN protein modulate Akt phosphorylation on serine 473, but not on threonine 308, in IGF-II-overexpressing rhabdomyosarcomas cells
    • Wan X, Helman LJ: Levels of PTEN protein modulate Akt phosphorylation on serine 473, but not on threonine 308, in IGF-II-overexpressing rhabdomyosarcomas cells. Oncogene 2003, 22:8205-8211
    • (2003) Oncogene , vol.22 , pp. 8205-8211
    • Wan, X.1    Helman, L.J.2
  • 59
    • 34250302647 scopus 로고    scopus 로고
    • PAX3 and PAX3-FKHR promote rhabdomyosarcoma cell survival through downregulation of PTEN
    • Li HG, Wang Q, Li HM, Kumar S, Parker C, Slevin M, Kumar P: PAX3 and PAX3-FKHR promote rhabdomyosarcoma cell survival through downregulation of PTEN. Cancer Lett 2007, 253:215-223
    • (2007) Cancer Lett , vol.253 , pp. 215-223
    • Li, H.G.1    Wang, Q.2    Li, H.M.3    Kumar, S.4    Parker, C.5    Slevin, M.6    Kumar, P.7
  • 61
    • 33144470613 scopus 로고    scopus 로고
    • Survivindirected RNA interference cocktail is a potent suppressor of tumour growth in vivo
    • Caldas H, Holloway MP, Hall BM, Qualman SJ, Altura RA: Survivindirected RNA interference cocktail is a potent suppressor of tumour growth in vivo. J Med Genet 2006, 43:119-128
    • (2006) J Med Genet , vol.43 , pp. 119-128
    • Caldas, H.1    Holloway, M.P.2    Hall, B.M.3    Qualman, S.J.4    Altura, R.A.5
  • 62
    • 45549100373 scopus 로고    scopus 로고
    • Genetic modeling of Ras-induced human rhabdomyosarcoma
    • Linardic CM, Counter CM: Genetic modeling of Ras-induced human rhabdomyosarcoma. Methods Enzymol 2008, 438:419-427
    • (2008) Methods Enzymol , vol.438 , pp. 419-427
    • Linardic, C.M.1    Counter, C.M.2
  • 63
    • 35148872765 scopus 로고    scopus 로고
    • Hedgehog-independent overexpression of transforming growth factor-beta1 in rhabdomyosarcoma of Patched1 mutant mice
    • Eichenmuller M, Bauer R, Von Schweinitz D, Hahn H, Kappler R: Hedgehog-independent overexpression of transforming growth factor-beta1 in rhabdomyosarcoma of Patched1 mutant mice. Int J Oncol 2007, 31:405-412
    • (2007) Int J Oncol , vol.31 , pp. 405-412
    • Eichenmuller, M.1    Bauer, R.2    Von Schweinitz, D.3    Hahn, H.4    Kappler, R.5
  • 70
    • 7544235883 scopus 로고    scopus 로고
    • Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: Implications for alveolar rhabdomyosarcoma cell of origin
    • Keller C, Hansen MS, Coffin CM, Capecchi MR: Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin. Genes Dev 2004, 18:2608-2613
    • (2004) Genes Dev , vol.18 , pp. 2608-2613
    • Keller, C.1    Hansen, M.S.2    Coffin, C.M.3    Capecchi, M.R.4
  • 71
    • 63449142234 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor pathway proteins in rhabdomyosarcoma: IGF-2 expression is associated with translocation-negative tumors
    • Makawita S, Ho M, Durbin AD, Thorner PS, Malkin D, Somers GR: Expression of insulin-like growth factor pathway proteins in rhabdomyosarcoma: IGF-2 expression is associated with translocation-negative tumors. Pediatr Dev Pathol 2008, 12:127-135
    • (2008) Pediatr Dev Pathol , vol.12 , pp. 127-135
    • Makawita, S.1    Ho, M.2    Durbin, A.D.3    Thorner, P.S.4    Malkin, D.5    Somers, G.R.6
  • 72
    • 0028229910 scopus 로고
    • Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma
    • Zhan S, Shapiro DN, Helman LJ: Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma. J Clin Invest 1994, 94:445-448
    • (1994) J Clin Invest , vol.94 , pp. 445-448
    • Zhan, S.1    Shapiro, D.N.2    Helman, L.J.3
  • 73
    • 34547654433 scopus 로고    scopus 로고
    • Overexpression of the cytotoxic T cell (CT) carbohydrate inhibits muscular dystrophy in the dyW mouse model of congenital muscular dystrophy 1A
    • Xu R, Chandrasekharan K, Yoon JH, Camboni M, Martin PT: Overexpression of the cytotoxic T cell (CT) carbohydrate inhibits muscular dystrophy in the dyW mouse model of congenital muscular dystrophy 1A. Am J Pathol 2007, 171:181-199
    • (2007) Am J Pathol , vol.171 , pp. 181-199
    • Xu, R.1    Chandrasekharan, K.2    Yoon, J.H.3    Camboni, M.4    Martin, P.T.5
  • 74
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2 - delta delta C(T) method
    • Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2 - delta delta C(T) method. Methods 2001, 25:402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 75
    • 34248379012 scopus 로고    scopus 로고
    • Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
    • Petitjean A, Mathe E, Kato S, Ishioka C, Tavtigian SV, Hainaut P, Olivier M: Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat 2007, 28:622-629
    • (2007) Hum Mutat , vol.28 , pp. 622-629
    • Petitjean, A.1    Mathe, E.2    Kato, S.3    Ishioka, C.4    Tavtigian, S.V.5    Hainaut, P.6    Olivier, M.7
  • 76
    • 0028340350 scopus 로고
    • Molecular cloning of a murine N-acetylgalactosamine transferase cDNA that determines expression of the T lymphocyte-specific CT oligosaccharide differentiation antigen
    • Smith PL, Lowe JB: Molecular cloning of a murine N-acetylgalactosamine transferase cDNA that determines expression of the T lymphocyte-specific CT oligosaccharide differentiation antigen. J Biol Chem 1994, 269:15162-15171
    • (1994) J Biol Chem , vol.269 , pp. 15162-15171
    • Smith, P.L.1    Lowe, J.B.2
  • 80
    • 0033007573 scopus 로고    scopus 로고
    • Characteristics of skeletal muscle in mdx mutant mice
    • De la Porte S, Morin S, Koenig J: Characteristics of skeletal muscle in mdx mutant mice. Int Rev Cytol 1999, 191:99-148
    • (1999) Int Rev Cytol , vol.191 , pp. 99-148
    • De la Porte, S.1    Morin, S.2    Koenig, J.3
  • 82
    • 33746445177 scopus 로고    scopus 로고
    • Nitric oxide-GAPDH-Siah: A novel cell death cascade
    • Hara MR, Snyder SH: Nitric oxide-GAPDH-Siah: a novel cell death cascade. Cell Mol Neurobiol 2006, 26:527-538
    • (2006) Cell Mol Neurobiol , vol.26 , pp. 527-538
    • Hara, M.R.1    Snyder, S.H.2
  • 83
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ: p53, the cellular gatekeeper for growth and division. Cell 1997, 88:323-331
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 84
    • 0036655060 scopus 로고    scopus 로고
    • Alternative and aberrant splicing of MDM2 mRNA in human cancer
    • Bartel F, Taubert H, Harris LC: Alternative and aberrant splicing of MDM2 mRNA in human cancer. Cancer Cell 2002, 2:9-15
    • (2002) Cancer Cell , vol.2 , pp. 9-15
    • Bartel, F.1    Taubert, H.2    Harris, L.C.3
  • 88
    • 0042196022 scopus 로고    scopus 로고
    • Dystroglycan glycosylation and its role in matrix binding in skeletal muscle
    • Martin PT: Dystroglycan glycosylation and its role in matrix binding in skeletal muscle. Glycobiology 2003, 13:55R-66R
    • (2003) Glycobiology , vol.13
    • Martin, P.T.1
  • 90
    • 0033504481 scopus 로고    scopus 로고
    • Duchenne muscular dystrophy and concomitant metastatic alveolar rhabdomyosarcoma
    • Rossbach HC, Lacson A, Grana NH, Barbosa JL: Duchenne muscular dystrophy and concomitant metastatic alveolar rhabdomyosarcoma. J Pediatr Hematol Oncol 1999, 21:528-530
    • (1999) J Pediatr Hematol Oncol , vol.21 , pp. 528-530
    • Rossbach, H.C.1    Lacson, A.2    Grana, N.H.3    Barbosa, J.L.4
  • 91
    • 0036113320 scopus 로고    scopus 로고
    • Duchenne muscular dystrophy-rhabdomyosarcoma, ichthyosis vulgaris/acute monoblastic leukemia: Association of rare genetic disorders and childhood malignant diseases
    • Jakab Z, Szegedi I, Balogh E, Kiss C, Olah E: Duchenne muscular dystrophy-rhabdomyosarcoma, ichthyosis vulgaris/acute monoblastic leukemia: association of rare genetic disorders and childhood malignant diseases. Med Pediatr Oncol 2002, 39:66-68
    • (2002) Med Pediatr Oncol , vol.39 , pp. 66-68
    • Jakab, Z.1    Szegedi, I.2    Balogh, E.3    Kiss, C.4    Olah, E.5
  • 94
    • 0036591684 scopus 로고    scopus 로고
    • Muscular dystrophies involving the dystrophin-glycoprotein complex: An overview of current mouse models
    • Durbeej M, Campbell KP: Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models. Curr Opin Genet Dev 2002, 12:349-361
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 349-361
    • Durbeej, M.1    Campbell, K.P.2
  • 95
    • 34347374860 scopus 로고    scopus 로고
    • Dystrophin-deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma
    • Chamberlain JS, Metzger J, Reyes M, Townsend D, Faulkner JA: Dystrophin-deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma. FASEB J 2007, 21:2195-2204
    • (2007) FASEB J , vol.21 , pp. 2195-2204
    • Chamberlain, J.S.1    Metzger, J.2    Reyes, M.3    Townsend, D.4    Faulkner, J.A.5
  • 96
    • 0027688044 scopus 로고
    • Immunohistochemical evaluation of dystrophin expression in small round cell tumors of childhood
    • Pinto A, Paslawski D, Sarnat HB, Parham DM: Immunohistochemical evaluation of dystrophin expression in small round cell tumors of childhood. Mod Pathol 1993, 6:679-683
    • (1993) Mod Pathol , vol.6 , pp. 679-683
    • Pinto, A.1    Paslawski, D.2    Sarnat, H.B.3    Parham, D.M.4
  • 102
    • 33845684374 scopus 로고    scopus 로고
    • Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice
    • Tsumura H, Yoshida T, Saito H, Imanaka-Yoshida K, Suzuki N: Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice. Oncogene 2006, 25:7673-7679
    • (2006) Oncogene , vol.25 , pp. 7673-7679
    • Tsumura, H.1    Yoshida, T.2    Saito, H.3    Imanaka-Yoshida, K.4    Suzuki, N.5
  • 103
    • 33748616037 scopus 로고    scopus 로고
    • A drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR
    • Galindo RL, Allport JA, Olson EN: A drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR. Proc Natl Acad Sci USA 2006, 103:13439-13444
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13439-13444
    • Galindo, R.L.1    Allport, J.A.2    Olson, E.N.3
  • 104
    • 77449101168 scopus 로고    scopus 로고
    • Mdm2-mediated ubiquitylation: P53 and beyond
    • DOI: 10.1038/cdd.2009.68
    • Marine JC, Lozano G: Mdm2-mediated ubiquitylation: p53 and beyond, Cell Death Differ 2009, DOI: 10.1038/cdd.2009.68
    • (2009) Cell Death Differ
    • Marine, J.C.1    Lozano, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.