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Volumn 16, Issue 12, 2009, Pages 1465-1476

Highly efficient eradication of intracranial glioblastoma using Eg5 siRNA combined with HVJ envelope

Author keywords

Apoptosis; Cell cycle arrest; Eg5; Glioblastoma; HVJ envelope; SiRNA

Indexed keywords

KINESIN; KINESIN LIKE 1 PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VIRUS VECTOR;

EID: 73849147949     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2009.99     Document Type: Article
Times cited : (24)

References (45)
  • 2
    • 0042922756 scopus 로고    scopus 로고
    • Relative survival rates and patterns of diagnosis analyzed by time period for individuals with primary malignant brain tumor, 1973-1997
    • Barnholtz-Sloan JS, Sloan AE, Schwartz AG. Relative survival rates and patterns of diagnosis analyzed by time period for individuals with primary malignant brain tumor, 1973-1997. J Neurosurg 2003; 99: 458-466.
    • (2003) J Neurosurg , vol.99 , pp. 458-466
    • Barnholtz-Sloan, J.S.1    Sloan, A.E.2    Schwartz, A.G.3
  • 3
    • 35148862753 scopus 로고    scopus 로고
    • Survival of patients with glioblastoma multiforme has not improved between 1993 and 2004: Analysis of 625 cases
    • Tait MJ, Petrik V, Loosemore A, Bell BA, Papadopoulos MC. Survival of patients with glioblastoma multiforme has not improved between 1993 and 2004: analysis of 625 cases. Br J Neurosurg 2007; 21: 496-500.
    • (2007) Br J Neurosurg , vol.21 , pp. 496-500
    • Tait, M.J.1    Petrik, V.2    Loosemore, A.3    Bell, B.A.4    Papadopoulos, M.C.5
  • 4
    • 33747163982 scopus 로고    scopus 로고
    • Recurrent glioblastoma multiforme: A review of natural history and management options
    • Hou LC, Veeravagu A, Hsu AR, Tse VC. Recurrent glioblastoma multiforme: a review of natural history and management options. Neurosurg Focus 2006; 20: E3.
    • (2006) Neurosurg Focus , vol.20
    • Hou, L.C.1    Veeravagu, A.2    Hsu, A.R.3    Tse, V.C.4
  • 5
    • 0035433029 scopus 로고    scopus 로고
    • Past and future of the mitotic spindle as an oncology target
    • Wood KW, Cornwell WD, Jackson JR. Past and future of the mitotic spindle as an oncology target. Curr Opin Pharmacol 2001; 1: 370-377.
    • (2001) Curr Opin Pharmacol , vol.1 , pp. 370-377
    • Wood, K.W.1    Cornwell, W.D.2    Jackson, J.R.3
  • 6
    • 0029011952 scopus 로고
    • Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle
    • Sawin KE, Mitchison TJ. Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle. Proc Natl Acad Sci USA 1995; 92: 4289-4293.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4289-4293
    • Sawin, K.E.1    Mitchison, T.J.2
  • 7
    • 0033545186 scopus 로고    scopus 로고
    • The bipolar kinesin, KLP61F, cross-links micro-tubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles
    • Sharp DJ, McDonald KL, Brown HM, Matthies HJ, Walczak C, Vale RD et al. The bipolar kinesin, KLP61F, cross-links micro-tubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles. J Cell Biol 1999; 144: 125-138.
    • (1999) J Cell Biol , vol.144 , pp. 125-138
    • Sharp, D.J.1    McDonald, K.L.2    Brown, H.M.3    Matthies, H.J.4    Walczak, C.5    Vale, R.D.6
  • 8
    • 0029417238 scopus 로고
    • Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
    • Blangy A, Lane HA, d'Hérin P, Harper M, Kress M, Nigg EA. Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell 1995; 83: 1159-1169.
    • (1995) Cell , vol.83 , pp. 1159-1169
    • Blangy, A.1    Lane, H.A.2    D'Hérin, P.3    Harper, M.4    Kress, M.5    Nigg, E.A.6
  • 9
    • 0029550441 scopus 로고
    • Novel mechanism of resistance to paclitaxel (Taxol) in human K562 leukemia cells by combined selection with PSC 833
    • Jaffrézou JP, Dumontet C, Derry WB, Durán G, Chen G, Tsuchiya E et al. Novel mechanism of resistance to paclitaxel (Taxol) in human K562 leukemia cells by combined selection with PSC 833. Oncol Res 1995; 7: 517-527.
    • (1995) Oncol Res , vol.7 , pp. 517-527
    • Jaffrézou, J.D.1
  • 10
    • 0036158822 scopus 로고    scopus 로고
    • Chemotherapy-induced peripheral neuropathy
    • Quasthoff S, Hartung HP. Chemotherapy-induced peripheral neuropathy. J Neurol 2002; 249: 9-17.
    • (2002) J Neurol , vol.249 , pp. 9-17
    • Quasthoff, S.1    Hartung, H.P.2
  • 11
  • 12
    • 20144388363 scopus 로고    scopus 로고
    • Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP
    • Cox CD, Breslin MJ, Mariano BJ, Coleman PJ, Buser CA, Walsh ES et al. Kinesin spindle protein (KSP) inhibitors. Part 1: the discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP. Bioorg Med Chem Lett 2005; 15: 2041-2045.
    • (2005) Bioorg Med Chem Lett , vol.15 , pp. 2041-2045
    • Cox, C.D.1    Breslin, M.J.2    Mariano, B.J.3    Coleman, P.J.4    Buser, C.A.5    Walsh, E.S.6
  • 13
    • 0242515795 scopus 로고    scopus 로고
    • A novel action of terpendole e on the motor activity of mitotic Kinesin Eg5
    • Nakazawa J, Yajima J, Usui T, Ueki M, Takatsuki A, Imoto M et al. A novel action of terpendole E on the motor activity of mitotic Kinesin Eg5. Chem Biol 2003; 10: 131-137.
    • (2003) Chem Biol , vol.10 , pp. 131-137
    • Nakazawa, J.1    Yajima, J.2    Usui, T.3    Ueki, M.4    Takatsuki, A.5    Imoto, M.6
  • 14
    • 5444274954 scopus 로고    scopus 로고
    • Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5
    • Brier S, Lemaire D, Debonis S, Forest E, Kozielski F. Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5. Biochemistry 2004; 43: 13072-13082.
    • (2004) Biochemistry , vol.43 , pp. 13072-13082
    • Brier, S.1    Lemaire, D.2    Debonis, S.3    Forest, E.4    Kozielski, F.5
  • 16
    • 22144463476 scopus 로고    scopus 로고
    • Development and biological evaluation of potent and specific inhibitors of mitotic kinesin Eg5
    • DOI 10.1002/cbic.200500005
    • Gartner M, Sunder-Plassmann N, Seiler J, Utz M, Vernos I, Surrey T et al. Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5. Chembiochem 2005; 6: 1173-1177. (Pubitemid 40978175)
    • (2005) ChemBioChem , vol.6 , Issue.7 , pp. 1173-1177
    • Gartner, M.1    Sunder-Plassmann, N.2    Seiler, J.3    Utz, M.4    Vernos, I.5    Surrey, T.6    Giannis, A.7
  • 18
    • 33845352935 scopus 로고    scopus 로고
    • Inhibitors of kinesin Eg5: Antiproliferative activity of monastrol analogues against human glioblastoma cells
    • Mü ller C, Gross D, Sarli V, Gartner M, Giannis A, Bernhardt G et al. Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells. Cancer Chemother Pharmacol 2007; 59: 157-164.
    • (2007) Cancer Chemother Pharmacol , vol.59 , pp. 157-164
    • Müller C, G.1
  • 19
    • 33644517511 scopus 로고    scopus 로고
    • Use of a chemically modified antisense oligonucleotide library to identify and validate Eg5 (kinesin-like 1) as a target for antineoplastic drug development
    • Koller E, Propp S, Zhang H, Zhao C, Xiao X, Chang M et al. Use of a chemically modified antisense oligonucleotide library to identify and validate Eg5 (kinesin-like 1) as a target for antineoplastic drug development. Cancer Res 2006; 66: 2059-2066.
    • (2006) Cancer Res , vol.66 , pp. 2059-2066
    • Koller, E.1    Propp, S.2    Zhang, H.3    Zhao, C.4    Xiao, X.5    Chang, M.6
  • 20
    • 2942724286 scopus 로고    scopus 로고
    • Ribozyme-and siRNA-mediated mRNA degradation: A general introduction
    • Sioud M. Ribozyme-and siRNA-mediated mRNA degradation: a general introduction. Methods Mol Biol 2004; 252: 1-8.
    • (2004) Methods Mol Biol , vol.252 , pp. 1-8
    • Sioud, M.1
  • 21
    • 3242677639 scopus 로고    scopus 로고
    • SiRNAs: Applications in functional genomics and potential as therapeutics
    • Dorsett Y, Tuschl T. siRNAs: applications in functional genomics and potential as therapeutics. Nat Rev Drug Discov 2004; 3: 318-329.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 318-329
    • Dorsett, Y.1    Tuschl, T.2
  • 22
    • 24144445346 scopus 로고    scopus 로고
    • Comparison of the suppressive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells
    • Miyagishi M, Hayashi M, Taira K. Comparison of the suppres-sive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells. Antisense Nucleic Acid Drug Dev 2003; 13: 1-7.
    • (2003) Antisense Nucleic Acid Drug Dev , vol.13 , pp. 1-7
    • Miyagishi, M.1    Hayashi, M.2    Taira, K.3
  • 23
    • 9144256376 scopus 로고    scopus 로고
    • SiRNA-based inhibition specific for mutant SOD1 with single nucleotide alternation in familial ALS, compared with ribozyme and DNA enzyme
    • Yokota T, Miyagishi M, Hino T, Matsumura R, Tasinato A, Urushitani M et al. siRNA-based inhibition specific for mutant SOD1 with single nucleotide alternation in familial ALS, compared with ribozyme and DNA enzyme. Biochem Biophys Res Commun 2004; 314: 283-291.
    • (2004) Biochem Biophys Res Commun , vol.314 , pp. 283-291
    • Yokota, T.1    Miyagishi, M.2    Hino, T.3    Matsumura, R.4    Tasinato, A.5    Urushitani, M.6
  • 24
    • 15444373116 scopus 로고    scopus 로고
    • RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
    • Urban-Klein B, Werth S, Abuharbeid S, Czubayko F, Aigner A. RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene Ther 2005; 12: 461-466.
    • (2005) Gene Ther , vol.12 , pp. 461-466
    • Urban-Klein, B.1    Werth, S.2    Abuharbeid, S.3    Czubayko, F.4    Aigner, A.5
  • 25
    • 0036664449 scopus 로고    scopus 로고
    • Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system
    • Kaneda Y, Nakajima T, Nishikawa T, Yamamoto S, Ikegami H, Suzuki N et al. Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system. Mol Ther 2002; 6: 219-226.
    • (2002) Mol Ther , vol.6 , pp. 219-226
    • Kaneda, Y.1    Nakajima, T.2    Nishikawa, T.3    Yamamoto, S.4    Ikegami, H.5    Suzuki, N.6
  • 26
    • 0141919523 scopus 로고    scopus 로고
    • New vector innovation for drug delivery: Development of fusigenic non-viral particles
    • Kaneda Y. New vector innovation for drug delivery: development of fusigenic non-viral particles. Curr Drug Targets 2003; 4: 599-602.
    • (2003) Curr Drug Targets , vol.4 , pp. 599-602
    • Kaneda, Y.1
  • 27
    • 33645234581 scopus 로고    scopus 로고
    • Development of HVJ envelope vector and its application to gene therapy
    • Kaneda Y, Yamamoto S, Nakajima T. Development of HVJ envelope vector and its application to gene therapy. Adv Genet 2005; 53: 307-332.
    • (2005) Adv Genet , vol.53 , pp. 307-332
    • Kaneda, Y.1    Yamamoto, S.2    Nakajima, T.3
  • 28
    • 23344453535 scopus 로고    scopus 로고
    • Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin
    • Ito M, Yamamoto S, Nimura K, Hiraoka K, Tamai K, Kaneda Y. Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin. J Gene Med 2005; 7: 1044-1052.
    • (2005) J Gene Med , vol.7 , pp. 1044-1052
    • Ito, M.1    Yamamoto, S.2    Nimura, K.3    Hiraoka, K.4    Tamai, K.5    Kaneda, Y.6
  • 29
    • 33646587663 scopus 로고    scopus 로고
    • Targeted chemotherapy against intraperitoneally disseminated colon carcinoma using a cationized gelatin-conjugated HVJ envelope vector
    • Mima H, Yamamoto S, Ito M, Tomoshige R, Tabata Y, Tamai K et al. Targeted chemotherapy against intraperitoneally disseminated colon carcinoma using a cationized gelatin-conjugated HVJ envelope vector. Mol Cancer Ther 2006; 5: 1021-1028.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1021-1028
    • Mima, H.1    Yamamoto, S.2    Ito, M.3    Tomoshige, R.4    Tabata, Y.5    Tamai, K.6
  • 30
    • 33846432377 scopus 로고    scopus 로고
    • Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells
    • Kurooka M, Kaneda Y. Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells. Cancer Res 2007; 67: 227-236.
    • (2007) Cancer Res , vol.67 , pp. 227-236
    • Kurooka, M.1    Kaneda, Y.2
  • 31
    • 35748961970 scopus 로고    scopus 로고
    • Intratumoral injection of inactivated Sendai virus particles elicits strong antitumor activity by enhancing local CXCL10 expression and systemic NK cell activation
    • Fujihara A, Kurooka M, Miki T, Kaneda Y. Intratumoral injection of inactivated Sendai virus particles elicits strong antitumor activity by enhancing local CXCL10 expression and systemic NK cell activation. Cancer Immunol Immunother 2008; 57: 73-84.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 73-84
    • Fujihara, A.1    Kurooka, M.2    Miki, T.3    Kaneda, Y.4
  • 32
    • 64249091007 scopus 로고    scopus 로고
    • Efficient eradication of hormone-resistant human prostate cancers by inactivated Sendai virus particle
    • Kawaguchi Y, Miyamoto Y, Inoue T, Kaneda Y. Efficient eradication of hormone-resistant human prostate cancers by inactivated Sendai virus particle. Int J Cancer 2009; 124: 2478-2487.
    • (2009) Int J Cancer , vol.124 , pp. 2478-2487
    • Kawaguchi, Y.1    Miyamoto, Y.2    Inoue, T.3    Kaneda, Y.4
  • 33
    • 0021258931 scopus 로고
    • Procarba-zine CCNU and vincristine (PCV) combination chemotherapy for brain tumors
    • Brufman G, Halpern J, Sulkes A, Catane R, Biran S. Procarba-zine, CCNU and vincristine (PCV) combination chemotherapy for brain tumors. Oncology 1984; 41: 239-241.
    • (1984) Oncology , vol.41 , pp. 239-241
    • Brufman, G.1    Halpern, J.2    Sulkes, A.3    Catane, R.4    Biran, S.5
  • 34
    • 33846172672 scopus 로고    scopus 로고
    • An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis
    • Tao W, South VJ, Diehl RE, Davide JP, Sepp-Lorenzino L, Fraley ME et al. An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis. Mol Cell Biol 2007; 27: 689-698.
    • (2007) Mol Cell Biol , vol.27 , pp. 689-698
    • Tao, W.1    South, V.J.2    Diehl, R.E.3    Davide, J.P.4    Sepp-Lorenzino, L.5    Fraley, M.E.6
  • 35
    • 15744404844 scopus 로고    scopus 로고
    • Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and-sensitive cancer cells
    • Marcus AI, Peters U, Thomas SL, Garrett S, Zelnak A, Kapoor TM et al. Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and-sensitive cancer cells. J Biol Chem 2005; 280: 11569-11577.
    • (2005) J Biol Chem , vol.280 , pp. 11569-11577
    • Marcus, A.I.1    Peters, U.2    Thomas, S.L.3    Garrett, S.4    Zelnak, A.5    Kapoor, T.M.6
  • 36
    • 4644263812 scopus 로고    scopus 로고
    • In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities
    • DeBonis S, Skoufias DA, Lebeau L, Lopez R, Robin G, Margolis RL et al. In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities. Mol Cancer Ther 2004; 3: 1079-1090.
    • (2004) Mol Cancer Ther , vol.3 , pp. 1079-1090
    • Debonis, S.1    Skoufias, D.A.2    Lebeau, L.3    Lopez, R.4    Robin, G.5    Margolis, R.L.6
  • 37
    • 44849127993 scopus 로고    scopus 로고
    • Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5
    • Shi J, Orth JD, Mitchison T. Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5. Cancer Res 2008; 68: 3269-3276.
    • (2008) Cancer Res , vol.68 , pp. 3269-3276
    • Shi, J.1    Orth, J.D.2    Mitchison, T.3
  • 38
    • 35348869384 scopus 로고    scopus 로고
    • Development of tissue-targeting hemagglutinating virus of Japan envelope vector for successful delivery of therapeutic gene to mouse skin
    • Kawachi M, Tamai K, Saga K, Yamazaki T, Fujita H, Shimbo T et al. Development of tissue-targeting hemagglutinating virus of Japan envelope vector for successful delivery of therapeutic gene to mouse skin. Hum Gene Ther 2007; 18: 881-894.
    • (2007) Hum Gene Ther , vol.18 , pp. 881-894
    • Kawachi, M.1    Tamai, K.2    Saga, K.3    Yamazaki, T.4    Fujita, H.5    Shimbo, T.6
  • 41
    • 0034184409 scopus 로고    scopus 로고
    • Molecular expression analysis of restrictive receptor for interleukin 13, a brain tumor-associated cancer/testis antigen
    • Debinski W, Gibo DM. Molecular expression analysis of restrictive receptor for interleukin 13, a brain tumor-associated cancer/testis antigen. Mol Med 2000; 6: 440-449.
    • (2000) Mol Med , vol.6 , pp. 440-449
    • Debinski, W.1    Gibo, D.M.2
  • 42
    • 0034575691 scopus 로고    scopus 로고
    • EGFRvIII as a promising target for antibody-based brain tumor therapy
    • Kuan CT, Wikstrand CJ, Bigner DD. EGFRvIII as a promising target for antibody-based brain tumor therapy. Brain Tumor Pathol 2000; 17: 71-78.
    • (2000) Brain Tumor Pathol , vol.17 , pp. 71-78
    • Kuan, C.T.1    Wikstrand, C.J.2    Bigner, D.D.3
  • 43
    • 39749085331 scopus 로고    scopus 로고
    • Applications of hemagglutinating virus of Japan in therapeutic delivery systems
    • Kaneda Y. Applications of hemagglutinating virus of Japan in therapeutic delivery systems. Expert Opin Drug Deliv 2008; 5: 221-233.
    • (2008) Expert Opin Drug Deliv , vol.5 , pp. 221-233
    • Kaneda, Y.1
  • 44
    • 33845956038 scopus 로고    scopus 로고
    • Combination of active and inactive siRNA targeting the mitotic kinesin Eg5 impairs silencing efficiency in several cancer cell lines
    • Formstecher E, Reverdy C, Cholay M, Planquette C, Trouplin V, Lehrmann H et al. Combination of active and inactive siRNA targeting the mitotic kinesin Eg5 impairs silencing efficiency in several cancer cell lines. Oligonucleotides 2006; 16: 387-394.
    • (2006) Oligonucleotides , vol.16 , pp. 387-394
    • Formstecher, E.1    Reverdy, C.2    Cholay, M.3    Planquette, C.4    Trouplin, V.5    Lehrmann, H.6
  • 45
    • 0033917495 scopus 로고    scopus 로고
    • Vascular apoptosis and involution in gliomas precede neovascularization: A novel concept for glioma growth and angiogenesis
    • Zagzag D, Amirnovin R, Greco MA, Yee H, Holash J, Wiegand SJ et al. Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis. Lab Invest 2000; 80: 837-849.
    • (2000) Lab Invest , vol.80 , pp. 837-849
    • Zagzag, D.1    Amirnovin, R.2    Greco, M.A.3    Yee, H.4    Holash, J.5    Wiegand, S.J.6


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