Enhanced generation of myeloid lineages in hematopoietic differentiation from embryonic stem cells by silencing transcriptional repressor Twist-2

Cloning and Stem Cells

Volumn 11, Issue 4, 2009, Pages 523-533

  Sharabi, Andrew B ^a   Lee, Sung Hyung ^b   Goodell, Margaret A ^a   Huang, Xue F ^b   Chen, Si Yi ^a,b  

^a CENTER FOR CELL AND GENE THERAPY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SHORT HAIRPIN RNA; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR TWIST 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; GENE SILENCING; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; CELL LINE; CELL LINEAGE; DOWN-REGULATION; EMBRYONIC STEM CELLS; GENE SILENCING; HEMATOPOIESIS; LIPOPOLYSACCHARIDES; MICE; MYELOID CELLS; TOLL-LIKE RECEPTOR 4; TWIST TRANSCRIPTION FACTOR;

MURINAE;

EID: 73849130622     PISSN: 15362302     EISSN: None     Source Type: Journal    
DOI: 10.1089/clo.2009.0020     Document Type: Article

References (39)

1. Beyer, K.S., Beauchamp, R.L., Lee, M.F., et al. (2007). Mediator subunit MED28 (Magicin) is a repressor of smooth muscle cell differentiation. J. Biol. Chem. 282, 32152-32157.
2. Bialek, P., Kern, B., Yang, X., et al. (2004). A twist code determines the onset of osteoblast differentiation. Dev. Cell 6, 423-435.
3. Chan, R.J., Johnson, S.A., Li, Y., et al. (2003). A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis. Blood 102, 2074-2080.
4. Chen, Z.F., and Behringer, R.R. (1995). twist is required in head mesenchyme for cranial neural tube morphogenesis. Genes Dev. 9, 686-699.
5. Copray, S., Balasubramaniyan, V., Levenga, J., et al. (2006). Olig2 overexpression induces the in vitro differentiation of neural stem cells into mature oligodendrocytes. Stem Cells 24, 1001-1010.
6. Dahl, L., Richter, K., Hagglund, A.C., et al. (2008). Lhx2 expression promotes self-renewal of a distinct multipotential hematopoietic progenitor cell in embryonic stem cell-derived embryoid bodies. PLoS ONE 3, e2025.
7. Dang, S.M., Kyba, M., Perlingeiro, R., et al. (2002). Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems. Bio-technol. Bioeng. 78, 442-453.
8. Docherty, K., Bernardo, A.S., and Vallier, L. (2007). Embryonic stem cell therapy for diabetes mellitus. Semin. Cell Dev. Biol. 18, 827-838.
9. Fehling, H.J., Lacaud, G., Kubo, A., et al. (2003). Tracking me-soderm induction and its specification to the hemangioblast during embryonic stem cell differentiation. Development 130, 4217-4227.
10. Hebrok, M., Wertz, K., and Fuchtbauer, E.M. (1994). M-twist is an inhibitor of muscle differentiation. Dev. Biol. 165, 537-544.
11. Hjiantoniou, E., Anayasa, M., Nicolaou, P., et al. (2008). Twist induces reversal of myotube formation. Differentiation 76, 182-192.
12. Jankovic, V., Ciarrocchi, A., Boccuni, P., et al. (2007). Id1 restrains myeloid commitment, maintaining the self-renewal capacity of hematopoietic stem cells. Proc. Natl. Acad. Sci. USA 104, 1260-1265.
13. Jhas, S., Ciura, S., Belanger-Jasmin, S., et al. (2006). Hes6 inhibits astrocyte differentiation and promotes neurogenesis through different mechanisms. J. Neurosci. 26, 11061-11071.
14. Krassowska, A., Gordon-Keylock, S., Samuel, K., et al. (2006). Promotion of haematopoietic activity in embryonic stem cells by the aorta-gonad- mesonephros microenvironment. Exp. Cell Res. 312, 3595-3603.
15. Kurosawa, H. (2007). Methods for inducing embryoid body formation: in vitro differentiation system of embryonic stem cells. J. Biosci. Bioeng. 103, 389-398.
16. Ledran, M.H., Krassowska, A., Armstrong, L., et al. (2008). Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches. Cell Stem Cell 3, 85-98.
17. Lee, S., Sharabi A., Huang, X.F., et al. (2009). Embryonic stem cells and mammary luminal progenitors directly sense and respond to microbial products. Stem Cells 27, 1604-1615.
18. Lee, Y.S., Lee, H.H., Park, J., et al. (2003). Twist2, a novel ADD1= SREBP1c interacting protein, represses the transcriptional activity of ADD1=SREBP1c. Nucleic Acids Res. 31, 7165-7174.
19. Mountford, J.C. (2008). Human embryonic stem cells: origins, characteristics and potential for regenerative therapy. Trans-fus. Med. 18, 1-12.
20. Murray, S.S., Glackin, C.A., Winters, K.A., et al. (1992). Expression of helix-loop-helix regulatory genes during differentiation of mouse osteoblastic cells. J. Bone Miner. Res. 7, 1131-1138.
21. Nagai, Y., Garrett, K.P., Ohta, S., et al. (2006). Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity 24, 801-812.
22. O'Rourke, M.P., Soo, K., Behringer, R.R., et al. (2002). Twist plays an essential role in FGF and SHH signal transduction during mouse limb development. Dev. Biol. 248, 143-156.
23. O'Rourke, M.P., and Tam, P.P. (2002). Twist functions in mouse development. Int. J. Dev. Biol. 46, 401-413.
24. Passier, R., van Laake, L.W., and Mummery, C.L. (2008). Stem-cell-based therapy and lessons from the heart. Nature 453, 322-329.
25. Rohwedel, J., Horak, V., Hebrok, M., et al. (1995). M-twist expression inhibits mouse embryonic stem cell-derived myo-genic differentiation in vitro. Exp Cell Res 220, 92-100.
26. Schroers, R., and Chen, S.Y. (2004). Lentiviral transduction of human dendritic cells. Methods Mol. Biol. 246, 451-459.
27. Sharabi, A.B., Aldrich, M., Sosic, D., et al. (2008). Twist-2 controls myeloid lineage development and function. PLoS Biol. 6, e316.
28. Shen, L., Evel-Kabler, K., Strube, R., et al. (2004). Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity. Nat. Biotechnol. 22, 1546-1553.
29. Smith, A.G., Heath, J.K., Donaldson, D.D., et al. (1988). Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 336, 688-690.
30. Sosic, D., Richardson, J.A., Yu, K., et al. (2003). Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity. Cell 112, 169-180.
31. Spicer, D.B., Rhee, J., Cheung, W.L., et al. (1996). Inhibition of myogenic bHLH and MEF2 transcription factors by the bHLH protein Twist. Science 272, 1476-1480.
32. Suter, D.M., and Krause, K.H. (2008). Neural commitment of embryonic stem cells: molecules, pathways and potential for cell therapy. J. Pathol. 215, 355-368.
33. Szabo, E., Qiu, Y., Baksh, S., et al. (2008). Calreticulin inhibits commitment to adipocyte differentiation. J. Cell Biol. 182, 103-116.
34. Thomson, J.A., Itskovitz-Eldor, J., Shapiro, S.S., et al. (1998). Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147.
35. Wang, Y.Y., Deng, X., Xu, L., et al. (2008). Bcl2 enhances induced hematopoietic differentiation of murine embryonic stem cells. Exp. Hematol. 36, 128-139.
36. Williams, R.L., Hilton, D.J., Pease, S., et al. (1988). Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 336, 684-687.
37. Yang, J., Mani, S.A., Donaher, J.L., et al. (2004). Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117, 927-939.
38. Zaehres, H., and Daley, G.Q. (2006). Transgene expression and RNA interference in embryonic stem cells. Methods Enzymol. 420, 49-64.
39. Zhang, J., Grindley, J.C., Yin, T., et al. (2006). PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature 441, 518-522.