APOE and lipid level synergy effects on declarative memory functioning in adulthood

European Psychologist

Volumn 14, Issue 4, 2009, Pages 268-278

  Sternäng, Ola ^a,b   Wahlin, Åke ^a,b   Adolfsson, Rolf ^c,d   Sleegers, Kristel ^e,f   Van Broeckhoven, Christine ^e   Nilsson, Lars Göran ^a,b  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b Stockholm Brain Institute   (Sweden)

^c UMEÅ UNIVERSITY   (Sweden)

^d SUNDERBY HOSPITAL   (Sweden)

^e DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^f UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

APOE; Interaction effects; Lipids; Longitudinal; Memory

Indexed keywords

EID: 73849104621     PISSN: 10169040     EISSN: None     Source Type: Journal    
DOI: 10.1027/1016-9040.14.4.268     Document Type: Article

References (55)

1. American Heart Association. (2008). Woman, heart disease, and stroke. Retrieved on February 1, 2008, from www.americanheart.org.
2. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed., revised). Washington, DC: American Psychiatric Association.
3. Bäckman, L., Small, B.J., & Wahlin, Å. (2001). Aging and memory: Cognitive and biological perspectives. In J.E. Birren & K.W. Schaie (Eds.), Handbook of the psychology of aging (pp. 349-377). San Diego, CA: Academic Press.
4. Bäckman, L., Small, B.J., Wahlin, Å., &Larsson, M. (2000). Cognitive functioning in very old age. In F.I.M. Craik & T.A. Salthouse (Eds.), The handbook of aging and cognition (pp. 499-558). Mahwah, NJ: Erlbaum.
5. Baltes, P.B. (1997). On the incomplete architecture of human ontogeny: Selection, optimization, and compensation as foundation of developmental theory. American Psychologist, 52, 366-380.
6. Bordens, K.S., & Abbott, B.B. (1988). Research design and methods: A process approach. Mountain View, CA: Mayfield.
7. Brayne, C., Matthews, F.E., McGee, M.A., & Jagger, C. (2001). Health and ill-health in the older population in England and Wales: The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Age and Ageing, 30, 53-62.
8. 12 or folate among adults aged 75 years and older. Neuropsychology, 18, 362-370.
9. Bunce, D., Kivipelto, M., & Wahlin, Å. (2005). Apolipoprotein E, B vitamins, and cognitive function in older adults. Journal of Gerontology: Psychological Sciences, 60B, P41-P48.
10. Collins, S., Ahima, R.S., & Kahn, B.B. (2005). Biology of adipose tissue. In C.R. Kahn, G.C.Weir, G.L.King, A.M. Jacobson, A.C. Moses, & R.J. Smith (Eds.), Joslin's Diabetes Mellitus (pp. 127-144). Philadelphia: Lippincott Williams & Wilkins.
11. Crabbe, J.C., & Weigel, R.M. (1987). Quantification of individual sensitivities to ethanol in selective breeding experiments: Difference scores versus regression residuals. Alcoholism: Clinical and Experimental Research, 11, 544-549.
12. Craig, S.R., Amin, R.V., Russell, D.W., & Paradise, N.F. (2000). Blood cholesterol screening: Influence of fasting state on cholesterol results and management decisions. Journal of General Internal Medicine, 15, 395-399.
13. Davignon, J., Gregg, R.E., & Sing, C.F. (1988). Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis, 8, 1-21.
14. de Frias, C.M., Bunce, D., Wahlin, Å., Adolfsson, R., Sleegers, K., Cruts, M. et al. (2007). Cholesterol and triglycerides moderate the effect of apolipoprotein E on memory functioning in older adults. Journal of Gerontology: Psychological Sciences, 62, P112-P118.
15. Elias, P.K., Elias, M.F., Robbins, M.A., & Budge, M.M. (2004). Blood pressure-related cognitive decline: Does age make a difference? Hypertension, 44, 631-636.
16. Evans, M.G. (1985). A Monte Carlo study of the effects of correlated method variance in moderated multiple regression analysis. Organizational Behavior and Human Decision Processes, 36, 305-323.
17. Farrer, L.A., Cupples, L.A., Haines, J.L., Hyman, B., Kukull, W.A., Mayeux, R. et al. (1997). Effects, of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: A meta-analysis. Journal of the American Medical Association, 278, 1349-1356.
18. Fazekas, F., Strasser-Fuchs, S., Kollegger, H., Berger, T., Kristoferitsch, W., Schmidt, H. et al. (2001). Apolipoprotein E ε4 is associated with rapid progression of multiple sclerosis. Neurology, 57, 853-857. (Pubitemid 32845507)
19. Fozard, J.L., Metter, E.J., & Brant, L.J. (1990). Next steps in describing aging and disease in longitudinal studies. Journal of Gerontology: Psychological Sciences, 45, P116-P127.
20. Gur, R.C., Mozley, L.H., Mozley, P.D., Resnick, S.M., Karp, J.S., Alavi, A. et al. (1995). Sex differences in regional cerebral glucose metabolism during a resting state. Science, 267, 528-531.
21. Helkala, E.-L., Niskanen, L., Viinamaki, H., Partanen, J., & Uusitupa, M. (1995). Short-term and long-term memory in elderly patients with NIDDM. Diabetes Care, 18, 681-685.
22. Herlitz, A., Airaksinen, E., & Nordström, E. (1999). Sex differences in episodic memory: The impact of verbal and visuospatial ability. Neuropsychology, 13, 590-597.
23. Institute of Medicine. (2001). Exploring the biological contributions to human health: Does sex matter? Washington, DC: National Academy Press.
24. Kelada, S.N., Eaton, D.L., Wang, S.S., Rothman, N.R., & Khoury, M.J. (2003). The role of genetic polymorphisms in environmental health. Environmental Health Perspectives, 111, 1055-1064.
25. Kilander, L., Nyman, H., Boberg, M., & Lithell, H. (1997). Cognitive function, vascular risk factors, and education. A crosssectional study based on a cohort of 70-year-old men. Journal of Internal Medicine, 242, 313-321.
26. Kruszynska, Y.T. (2003). Normal metabolism: The physiology of fuel homeostasis. In J.C. Pickup & G. Williams (Eds.), Textbook of diabetes 1 (pp. 9.1-9.38). Oxford, UK: Blackwell Science Ltd.
27. Mahley, R.W., & Rall, S.C. Jr. (2000). Apolipoprotein E: Far more than a lipid transport protein. Annual Review of Genomics and Human Genetics, 1, 507-537.
28. Martin, A., Wiggs, C.L., Lalonde, F., & Mack, C. (1994). Word retrieval to letter and semantic cues: A double dissociation in normal subjects using interference tasks. Neuropsychologia, 32, 1487-1494.
29. McClelland, G.H., & Judd, C.M. (1993). Statistical difficulties of detecting interactions and moderator effects. Psychological Bulletin, 114, 376-390.
30. Moscovitch, M., & Melo, B. (1997). Strategic retrieval and the frontal lobes: Evidence from confabulation and amnesia. Neuropsychologia, 35, 1017-1034.
31. Nilsson, L.-G., Bäckman, L., Erngrund, K., Nyberg, L., Adolfsson, R., Bucht, G. et al. (1997). The Betula prospective cohort study: Memory, health, and aging. Aging, Neuropsychology, and Cognition, 4, 1-32.
32. Nilsson, L.-G., Adolfsson, R., Bäckman, L., de Frias, C.M., Molander, B., & Nyberg, L. (2004). Betula: A prospective cohort study on memory, health, and aging. Aging, Neuropsychology, and Cognition, 11, 134-148.
33. Nilsson, L.-G., Adolfsson, R., Bäckman, L., Cruts, M., Nyberg, L., Small, B.J. et al. (2006). The influence of APOE status on episodic and semantic memory: Data from a population-based study. Neuropsychology, 20, 645-657.
34. Nyberg, L., Maitland, S.B., Rönnlund, M., Bäckman, L., Dixon, R.A., Wahlin, Å. et al. (2003). Selective adult age differences in an age-invariant multifactor model of declarative memory. Psychology and Aging, 18, 149-160.
35. Perlmuter, L.C., Nathan, D.M., Goldfinger, S.H., Russo, P.A., Yates, J., & Larkin, M. (1988). Triglyceride levels affect cognitive function in noninsulin-dependent diabetics. Journal of Diabetic Complications, 2, 210-213.
36. Riby, L.M., McMurtrie, H., Smallwood, J., Ballantyne, C., Meikle, A., & Smith, E. (2006). The facilitative effects of glucose ingestion on memory retrieval in younger and older adults: Is task difficulty or task domain critical? British Journal of Nutrition, 95, 414-420.
37. Salway, J.G. (2004). Metabolism at a glance. Oxford: Blackwell.
38. Schaie, K.W. (1994). The course of adult intellectual development. American Psychologist, 49, 304-313.
39. Sing, C.F., & Davignon, J. (1985). Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation. American Journal of Human Genetics, 37, 268-285.
40. Small, B.J., Graves, A.B., McEvoy, C.L., Crawford, F.C., Mullan, M., & Mortimer, J.A. (2000). Is APOE-ε4 a risk factor for cognitive impairment in normal aging? Neurology, 54, 2082-2088.
41. Small, B.J., Rosnick, C.B., Fratiglioni, L., & Bäckman, L. (2004). Apolipoprotein E and cognitive performance: A meta-analysis, Psychology and Aging, 19, 592-600.
42. Tabachnik, B.G., & Fidell, L.S. (2001). Using multivariate statistics (4th ed.). Needham Heights, MA: Allyn & Bacon.
43. Thilers, P.P., MacDonald, S.W.S., & Herlitz, A. (2006). The association between endogenous free testosterone and cognitive performance: A population-based study in 35-90-year-old men and women. Psychoneuroendocrinology, 31, 565-576.
44. Tulving, E. (2002). Episodic memory: From mind to brain. Annual Review of Psychology, 53, 1-25.
45. van Exel, E., de Craen, A.J.M., Gusseklo, J., Houx, P., Bootsmavan der Wiel, A., Macfarlane, P.W. et al. (2002). Association between high-density lipoprotein and cognitive impairment in the oldest old. Annals of Neurology, 51, 716-721.
46. Voyer, D., Voyer, S., & Bryden, M.P. (1995).Magnitude of sex differences in spatial abilities: Ameta-analysis and consideration of critical variables. Psychological Bulletin, 117, 250-270.
47. Wahlin, Å. (2004). Health, disease, and cognitive functioning in old age. In R.A. Dixon, L. Bäckman, & L.-G. Nilsson (Eds.), New frontiers in cognitive aging (pp. 279-302). Oxford, UK: Oxford University Press.
48. Wahlin, Å., Bäckman, L., Mäntylä, T., Herlitz, A., Viitanen, M., & Winblad, B. (1993). Prior knowledge and face recognition in a community-based sample of healthy, very old adults. Journal of Gerontology: Psychological Sciences, 48, P54-P61.
49. Wahlin, Å., MacDonald, S.W.S., de Frias, C.M., Nilsson, L.-G., & Dixon, R.A. (2006). How do health and biological age influence chronological age and sex differences in cognitive aging: Moderating, mediating, or both? Psychology and Aging, 21, 318-332.
50. Weiss, E.M., Ragland, J.D., Brensinger, C.M., Bilker, W.B., Deisenhammer, E.A., & Delazer, M. (2006). Sex differences in clustering and switching in verbal fluency tasks. Journal of the International Neuropsychological Society, 12, 502-509.
51. Wilson, D.M., Craig, D., McIlroy, S.P., & Passmore, A.P. (2005). Vascular cognitive impairment. Reviews in Clinical Gerontology, 14, 45-53.
52. Winnock, M., Letenneur, L., Jacqmin-Gadda, H., Dallongeville, J., Amouyel, P., & Dartigues, J.F. (2002). Longitudinal analysis of the effect of apolipoprotein E ε4 and education on cognitive performance in elderly subjects: The PAQUID study. Journal of Neurology, Neurosurgery, and Psychiatry, 72, 794-797.
53. Yaffe, K., Barrett-Connor, E., Lin, F., & Grady, D. (2002). Serum lipoprotein levels, statin use, and cognitive function in older women. Archives of Neurology, 59, 378-384.
54. Zannis, V.I., Kardassis, D., & Zanni, E.E. (1993). Genetic mutations affecting human lipoproteins, their receptors, and their enzymes. Advances in Human Genetics, 21, 145-319.
55. Zhang, J., Muldoon, M.F., & McKeown, R.E. (2004). Serum cholesterol concentrations are associated with visuomotor speed in men: Findings from the third National Health and Nutrition Examination Survey, 1988-1994. American Journal of Clinical Nutrition, 80, 291-298.