Human cardiac inwardly-rectifying K+ channel Kir2.1b is inhibited by direct protein kinase C-dependent regulation in human isolated cardiomyocytes and in an expression system

Circulation

Volumn 106, Issue 12, 2002, Pages 1493-1499

  Karle, Christoph A ^a   Zitron, Edgar ^a   Zhang, Wei ^a   Wendt Nordahl, Gunnar ^a   Kathöfer, Sven ^a   Thomas, Dierk ^a   Gut, Bernd ^a   Scholz, Eberhard ^a   Vahl, Christian Friedrich ^a   Katus, Hugo A ^a   Kiehn, Johann ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Arrhythmia; Electrophysiology; Ion channels; Signal transduction

Indexed keywords

CHELERYTHRINE; CHEMICAL COMPOUND; ENZYME ACTIVATOR; GLYCEROL 2 ACETATE 1 OLEATE; PHORBOL; PHORBOL 13 ACETATE 12 MYRISTATE; POTASSIUM CHANNEL; PROTEIN KINASE C; STAUROSPORINE; THYMELEATOXIN; TOXIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CLONE; CONTROLLED STUDY; DRUG EFFECT; ELECTRIC CURRENT; ENZYME REGULATION; GENE EXPRESSION SYSTEM; GENE MUTATION; HEART ATRIUM; HEART MUSCLE CELL; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; ISOLATED ORGAN; LABORATORY; MEASUREMENT; OOCYTE; PATCH CLAMP; PHOSPHORYLATION; POTASSIUM CURRENT; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; ATRIAL FUNCTION; CELLS, CULTURED; ELECTRIC CONDUCTIVITY; ENZYME INHIBITORS; HEART; HEART ATRIA; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MYOCARDIUM; OOCYTES; PHOSPHORYLATION; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN KINASE C; SEQUENCE ALIGNMENT; TETRADECANOYLPHORBOL ACETATE; XENOPUS;

EID: 0037126016     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000029747.53262.5C     Document Type: Article

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