Development of high-throughput chemical extraction techniques and quantitative HPLC-MS/MS (SRM) assays for clinically relevant plasma proteins

Journal of Proteome Research

Volumn 9, Issue 1, 2010, Pages 333-340

  Barton, Chris ^a   Kay, Richard G ^a   Gentzer, Wolfgang ^b   Vitzthum, Frank ^b   Pleasance, Steve ^a  

^a Quotient Bioresearch Ltd   (United Kingdom)

^b Siemens Healthcare Diagnostics Products GmbH   (Germany)

Author keywords

ACN depletion; Clinical reference material; IGF I; Plasma; Quantitation; SPE; SRM; Standard human plasma; uHPLC MS MS

Indexed keywords

BIOLOGICAL MARKER; GROWTH HORMONE; PLASMA PROTEIN; SOMATOMEDIN C;

ACCURACY; ARTICLE; CONTROLLED STUDY; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOASSAY; INTERMETHOD COMPARISON; MACROMOLECULE; MASS SPECTROMETRY; MOLECULAR WEIGHT; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REACTION ANALYSIS; SOLID PHASE EXTRACTION;

ACETONITRILES; BLOOD PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; INSULIN-LIKE GROWTH FACTOR I; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 73649147741     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr900658d     Document Type: Article

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