Determination of basic drugs of abuse in human serum by online extraction and LC-MS/MS

Analytical and Bioanalytical Chemistry

Volumn 395, Issue 8, 2009, Pages 2499-2507

  Ferreirós Bouzas, Nerea ^a   Dresen, Sebastian ^a   Munz, Barbara ^a   Weinmann, Wolfgang ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Drugs of abuse; Online extraction; Quantitation; Tandem mass spectrometry; Validation

Indexed keywords

ANALYTES; ANALYTICAL COLUMNS; BASIC DRUGS; DEUTERATED ANALOGUE; DRIVING UNDER THE INFLUENCE; DRUGS OF ABUSE; ELUTION GRADIENT; EXTRACTION COLUMNS; HUMAN SERUM; LC-MS/MS; LIMITS OF QUANTITATIONS; MATRIX EFFECTS; MULTIPLE REACTION MONITORING; ONLINE EXTRACTION; POLAR ANALYTES; PROTEIN PRECIPITATION; RELATIVE STANDARD DEVIATIONS; SAMPLE PREPARATION; SOLID-PHASE EXTRACTION; SULPHATES; TANDEM MASS SPECTROMETRY;

BODY FLUIDS; CENTRIFUGATION; CHROMATOGRAPHIC ANALYSIS; DEUTERIUM; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; PROTEINS;

SOLVENT EXTRACTION;

NARCOTIC AGENT;

ARTICLE; BLOOD; DRUG MONITORING; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; METHODOLOGY; STANDARD; SUBSTANCE ABUSE;

CHROMATOGRAPHY, LIQUID; DRUG MONITORING; HUMANS; NARCOTICS; REFERENCE STANDARDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBSTANCE ABUSE DETECTION;

EID: 71449090389     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-009-3036-x     Document Type: Article

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