vHNF1 functions in distinct regulatory circuits to control ureteric bud branching and early nephrogenesis

Development

Volumn 137, Issue 2, 2010, Pages 347-357

  Lokmane, Ludmilla ^a,b   Heliot, Claire ^a,b   Garcia Villalba, Pilar ^a,b   Fabre, Mélanie ^a,b   Cereghini, Silvia ^a,b  

^a CNRS   (France)

^b INSERM   (France)

Author keywords

Early nephrogenesis; Homeodomain transcription factor; Mouse mosaic and tetraploid chimera analysis; Ureteric bud branching; Urogenital tract development

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 1BETA; WNT PROTEIN; WNT9B PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO PATTERN FORMATION; EMBRYONAL TISSUE; GENE CONTROL; GENE FUNCTION; GENE IDENTIFICATION; KIDNEY DEVELOPMENT; MORPHOGENESIS; MOSAICISM; MOUSE; MUELLERIAN DUCT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; URETERIC BUD BRANCHING;

ANIMALS; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEPATOCYTE NUCLEAR FACTOR 1-BETA; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KIDNEY; MICE; ORGANOGENESIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; URETER;

WOLFFIA;

EID: 73649124593     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.042226     Document Type: Article

References (50)

1. Barbacci, E., Reber, M., Ott, M. O., Breillat, C., Huetz, F. and Cereghini, S. (1999). Variant hepatocyte nuclear factor 1 is required for visceral endoderm specification. Development 126, 4795-4805.
2. Barbacci, E., Chalkiadaki, A., Masdeu, C., Haumaitre, C., Lokmane, L., Loirat, C., Cloarec, S., Talianidis, I., Bellanne-Chantelot, C. and Cereghini, S. (2004). HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment. Hum. Mol. Genet. 13, 3139-3149.
3. Bellanne-Chantelot, C., Chauveau, D., Gautier, J. F., Dubois-Laforgue, D., Clauin, S., Beaufils, S., Wilhelm, J. M., Boitard, C., Noel, L. H., Velho, G. et al. (2004). Clinical spectrum associated with hepatocyte nuclear factor-1beta mutations. Ann. Intern. Med. 140, 510-517.
4. Bohn, S., Thomas, H., Turan, G., Ellard, S., Bingham, C., Hattersley, A. T. and Ryffel, G. U. (2003). Distinct molecular and morphogenetic properties of mutations in the human HNF1beta gene that lead to defective kidney development. J. Am. Soc. Nephrol. 14, 2033-2041.
5. Bouchard, M. (2004). Transcriptional control of kidney development. Differentiation 72, 295-306.
6. Bouchard, M., Souabni, A., Mandler, M., Neubuser, A. and Busslinger, M. (2002). Nephric lineage specification by Pax2 and Pax8. Genes Dev. 16, 2958-2970.
7. Bridgewater, D., Cox, B., Cain, J., Lau, A., Athaide, V., Gill, P. S., Kuure, S., Sainio, K. and Rosenblum, N. D. (2008). Canonical WNT/ beta-catenin signaling is required for ureteric branching. Dev. Biol. 317, 83-94.
8. Brunskill, E. W., Aronow, B. J., Georgas, K., Rumballe, B., Valerius, M. T., Aronow, J., Kaimal, V., Jegga, A. G., Yu, J., Grimmond, S. et al. (2008). Atlas of gene expression in the developing kidney at microanatomic resolution. Dev. Cell 15, 781-791.
9. Carroll, T. J., Park, J. S., Hayashi, S., Majumdar, A. and McMahon, A. P. (2005). Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev. Cell 9, 283-292.
10. Chi, X., Michos, O., Shakya, R., Riccio, P., Enomoto, H., Licht, J. D., Asai, N., Takahashi, M., Ohgami, N., Kato, M. et al. (2009). Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis. Dev. Cell 17, 199-209.
11. Costantini, F. and Shakya, R. (2006). GDNF/Ret signaling and the development of the kidney. BioEssays 28, 117-127.
12. Donovan, M. J., Natoli, T. A., Sainio, K., Amstutz, A., Jaenisch, R., Sariola, H. and Kreidberg, J. A. (1999). Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud. Dev. Genet. 24, 252-262.
13. Dressler, G. R. (2006). The cellular basis of kidney development. Annu. Rev. Cell Dev. Biol. 22, 509-529.
14. Dudley, A. T., Lyons, K. M. and Robertson, E. J. (1995). A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 9, 2795-2807.
15. Edghill, E. L., Bingham, C., Ellard, S. and Hattersley, A. T. (2006). Mutations in hepatocyte nuclear factor-1beta and their related phenotypes. J. Med. Genet. 43, 84-90.
16. Ghabrial, A. S. and Krasnow, M. A. (2006). Social interactions among epithelial cells during tracheal branching morphogenesis. Nature 441, 746-749.
17. Gresh, L., Fischer, E., Reimann, A., Tanguy, M., Garbay, S., Shao, X., Hiesberger, T., Fiette, L., Igarashi, P., Yaniv, M. et al. (2004). A transcriptional network in polycystic kidney disease. EMBO J. 23, 1657-1668.
18. Grieshammer, U., Cebrian, C., Ilagan, R., Meyers, E., Herzlinger, D. and Martin, G. R. (2005). FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development 132, 3847-3857.
19. Grote, D., Boualia, S. K., Souabni, A., Merkel, C., Chi, X., Costantini, F., Carroll, T. and Bouchard, M. (2008). Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction. PLoS Genet. 4, e1000316.
20. Haumaitre, C., Barbacci, E., Jenny, M., Ott, M. O., Gradwohl, G. and Cereghini, S. (2005). Lack of TCF2/vHNF1 in mice leads to pancreas agenesis. Proc. Natl. Acad. Sci. USA 102, 1490-1495.
21. Haumaitre, C., Fabre, M., Cormier, S., Baumann, C., Delezoide, A. L. and Cereghini, S. (2006). Severe pancreas hypoplasia and multicystic renal dysplasia in two human fetuses carrying novel HNF1beta/MODY5 mutations. Hum. Mol. Genet. 15, 2363-2375.
22. Hayashi, S., Lewis, P., Pevny, L. and McMahon, A. P. (2002). Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Mech. Dev. 119 Suppl. 1, S97-S101.
23. Hiesberger, T., Bai, Y., Shao, X., McNally, B. T., Sinclair, A. M., Tian, X., Somlo, S. and Igarashi, P. (2004). Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice. J. Clin. Invest. 113, 814-825.
24. Karner, C. M., Chirumamilla, R., Aoki, S., Igarashi, P., Wallingford, J. B. and Carroll, T. J. (2009). Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis. Nat. Genet. 41, 793-799.
25. Kispert, A., Vainio, S. and McMahon, A. P. (1998). Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development 125, 4225-4234.
26. Kobayashi, A., Kwan, K. M., Carroll, T. J., McMahon, A. P., Mendelsohn, C. L. and Behringer, R. R. (2005). Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development. Development 132, 2809-2823.
27. Kuschert, S., Rowitch, D. H., Haenig, B., McMahon, A. P. and Kispert, A. (2001). Characterization of Pax-2 regulatory sequences that direct transgene expression in the Wolffian duct and its derivatives. Dev. Biol. 229, 128-140.
28. Lim, K. C., Lakshmanan, G., Crawford, S. E., Gu, Y., Grosveld, F. and Engel, J. D. (2000). Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system. Nat. Genet. 25, 209-212.
29. Lin, Y., Zhang, S., Tuukkanen, J., Peltoketo, H., Pihlajaniemi, T. and Vainio, S. (2003). Patterning parameters associated with the branching of the ureteric bud regulated by epithelial-mesenchymal interactions. Int. J. Dev. Biol. 47, 3-13.
30. Lindner, T. H., Njolstad, P. R., Horikawa, Y., Bostad, L., Bell, G. I. and Sovik, O. (1999). A novel syndrome of diabetes mellitus, renal dysfunction and genital malformation associated with a partial deletion of the pseudo-POU domain of hepatocyte nuclear factor-1beta. Hum. Mol. Genet. 8, 2001-2008.
31. Lokmane, L., Haumaitre, C., Garcia-Villalba, P., Anselme, I., Schneider- Maunoury, S. and Cereghini, S. (2008). Crucial role of vHNF1 in vertebrate hepatic specification. Development 135, 2777-2786.
32. Majumdar, A., Vainio, S., Kispert, A., McMahon, J. and McMahon, A. P. (2003). Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development 130, 3175-3185.
33. Marose, T. D., Merkel, C. E., McMahon, A. P. and Carroll, T. J. (2008). Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state. Dev. Biol. 314, 112-126.
34. Michael, L. and Davies, J. A. (2004). Pattern and regulation of cell proliferation during murine ureteric bud development. J. Anat. 204, 241-255.
35. Miyamoto, N., Yoshida, M., Kuratani, S., Matsuo, I. and Aizawa, S. (1997). Defects of urogenital development in mice lacking Emx2. Development 124, 1653-1664.
36. Miyazaki, Y., Oshima, K., Fogo, A., Hogan, B. L. and Ichikawa, I. (2000). Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter. J. Clin. Invest. 105, 863-873.
37. Park, J. S., Valerius, M. T. and McMahon, A. P. (2007). Wnt/ beta-catenin signaling regulates nephron induction during mouse kidney development. Development 134, 2533-2539.
38. Pedersen, A., Skjong, C. and Shawlot, W. (2005). Lim 1 is required for nephric duct extension and ureteric bud morphogenesis. Dev. Biol. 288, 571-581.
39. Perantoni, A. O., Timofeeva, O., Naillat, F., Richman, C., Pajni-Underwood, S., Wilson, C., Vainio, S., Dove, L. F. and Lewandoski, M. (2005). Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development. Development 132, 3859-3871.
40. Pope, J. C. t., Brock, J. W., 3rd, Adams, M. C., Stephens, F. D. and Ichikawa, I. (1999). How they begin and how they end: classic and new theories for the development and deterioration of congenital anomalies of the kidney and urinary tract, CAKUT. J. Am. Soc. Nephrol. 10, 2018-2028.
41. Reber, M. and Cereghini, S. (2001). Variant hepatocyte nuclear factor 1 expression in the mouse genital tract. Mech. Dev. 100, 75-78.
42. Saxen, L. and Sariola, H. (1987). Early organogenesis of the kidney. Pediatr. Nephrol. 1, 385-392.
43. Schedl, A. (2007). Renal abnormalities and their developmental origin. Nat. Rev. Genet. 8, 791-802.
44. Schmidt-Ott, K. M., Yang, J., Chen, X., Wang, H., Paragas, N., Mori, K., Li, J. Y., Lu, B., Costantini, F., Schiffer, M. et al. (2005). Novel regulators of kidney development from the tips of the ureteric bud. J. Am. Soc. Nephrol. 16, 1993-2002.
45. Shakya, R., Watanabe, T. and Costantini, F. (2005). The role of GDNF/Ret signaling in ureteric bud cell fate and branching morphogenesis. Dev. Cell 8, 65-74.
46. Stark, K., Vainio, S., Vassileva, G. and McMahon, A. P. (1994). Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372, 679-683.
47. Sun, Z. and Hopkins, N. (2001). vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain. Genes Dev. 15, 3217-3229.
48. Torres, M., Gomez-Pardo, E., Dressler, G. R. and Gruss, P. (1995). Pax-2 controls multiple steps of urogenital development. Development 121, 4057-4065.
49. Vainio, S. and Lin, Y. (2002). Coordinating early kidney development: lessons from gene targeting. Nat. Rev. Genet. 3, 533-543.
50. Xu, P. X., Adams, J., Peters, H., Brown, M. C., Heaney, S. and Maas, R. (1999). Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia. Nat. Genet. 23, 113-117.