PKB/Akt activation inhibits p53-mediated HIF1A degradation that is independent of MDM2

Journal of Cellular Physiology

Volumn 222, Issue 3, 2010, Pages 635-639

  Choy, Mun Kit ^a   Movassagh, Mehregan ^a   Bennett, Martin R ^a   Foo, Roger S Y ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; DEFEROXAMINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P53; UBIQUITIN PROTEIN LIGASE E3;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; FIBROBLAST; GENE; GENE TARGETING; HEART MUSCLE CELL; IN VITRO STUDY; MOUSE; MOUSE EMBRYO; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RAT; UBIQUITINATION; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CARDIOMEGALY; CELL LINE; CELL SIZE; CHROMONES; DEFEROXAMINE; DISEASE MODELS, ANIMAL; FIBROBLASTS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, KNOCKOUT; MORPHOLINES; MYOBLASTS, CARDIAC; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MDM2; RATS; RNA, MESSENGER; SERINE; TIME FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINATION;

EID: 73649094752     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21980     Document Type: Article

References (16)

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