Effect of the histone deacetylase inhibitor trichostatin A on the metabolome of cultured primary hepatocytes

Journal of Proteome Research

Volumn 9, Issue 1, 2010, Pages 413-419

  Ellis, James K ^a   Chan, Pui Hei ^a   Doktorova, Tatyana ^b   Athersuch, Toby J ^a   Cavill, Rachel ^a   Vanhaecke, Tamara ^c   Rogiers, Vera ^b   Vinken, Mathieu ^b   Nicholson, Jeremy K ^a   Ebbels, Timothy M D ^a   Keun, Hector C ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c NONE

Author keywords

HDACi; Metabolic profiling; Primary hepatocytes; Trichostatin A; Xenobiotic metabolism

Indexed keywords

3 HYDROXYBUTYRIC ACID; ADENOSINE; GLUTATHIONE; GLYCEROPHOSPHORYLCHOLINE; GLYCINE; GLYCOGEN; HISTONE DEACETYLASE INHIBITOR; HYPOXANTHINE; INOSINE; TRICHOSTATIN A;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; LIVER CELL CULTURE; LIVER METABOLISM; METABOLOMICS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; XENOBIOTIC METABOLISM;

ANIMALS; CELLS, CULTURED; HEPATOCYTES; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HYDROXAMIC ACIDS; METABOLOME; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; RATS;

RATTUS;

EID: 73649090416     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr9007656     Document Type: Article

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