Trichostatin a enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes

Toxicological Sciences

Volumn 91, Issue 2, 2006, Pages 484-492

  Vinken, Mathieu ^a,d   Henkens, Tom ^a   Vanhaecke, Tamara ^a   Papeleu, Peggy ^a   Geerts, Albert ^a   Van Rossen, Elke ^a   Chipman, James Kevin ^b   Meda, Paolo ^c   Rogiers, Vera ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d RESEARCH FOUNDATION FLANDERS FWO   (Belgium)

Author keywords

Connexin; GJIC; HDAC inhibitor; Primary hepatocyte culture; TSA

Indexed keywords

DYE; GAP JUNCTION PROTEIN; HISTONE DEACETYLASE INHIBITOR; TRICHOSTATIN A;

ANIMAL CELL; ARTICLE; BIOLOGICAL MODEL; CELL COMMUNICATION; CELL COMPARTMENTALIZATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOL; GAP JUNCTION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOMEOSTASIS; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; LIVER CELL; LIVER CELL CULTURE; LIVER FUNCTION; MONITORING; NONHUMAN; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; RAT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOXICITY TESTING;

ACETYLATION; ANIMALS; CELL COMMUNICATION; CELLS, CULTURED; CONNEXINS; GAP JUNCTIONS; GENE EXPRESSION REGULATION; HEPATOCYTES; HISTONE DEACETYLASES; HISTONES; HYDROXAMIC ACIDS; L-LACTATE DEHYDROGENASE; MALE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 33744801133     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfj152     Document Type: Article

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