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Volumn 13, Issue 9 B, 2009, Pages 3497-3516

Control of chondrocyte gene expression by actin dynamics: A novel role of cholesterol/Ror-α signalling in endochondral bone growth

Author keywords

Actin cytoskeleton; Cholesterol; Chondrocytes; Hypertrophy; Microarray; Nuclear receptors; Rho GTPases; Ror

Indexed keywords

ACTIN; CHOLESTEROL; CYTOCHALASIN D; RETINOID RELATED ORPHAN RECEPTOR ALPHA;

EID: 73549119107     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2009.00684.x     Document Type: Article
Times cited : (30)

References (65)
  • 1
    • 0028067659 scopus 로고
    • Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes
    • Hunziker EB. Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes. Microsc Res Tech. 1994, 28:505-19.
    • (1994) Microsc Res Tech. , vol.28 , pp. 505-519
    • Hunziker, E.B.1
  • 2
    • 0032125265 scopus 로고    scopus 로고
    • Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones
    • Noonan KJ, Hunziker EB, Nessler J. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. J Orthop Res. 1998, 16:500-8.
    • (1998) J Orthop Res. , vol.16 , pp. 500-508
    • Noonan, K.J.1    Hunziker, E.B.2    Nessler, J.3    et al4
  • 3
    • 0036227738 scopus 로고    scopus 로고
    • The role of the resting zone in growth plate chondrogenesis
    • Abad V, Meyers JL, Weise M. The role of the resting zone in growth plate chondrogenesis. Endocrinology. 2002, 143:1851-7.
    • (2002) Endocrinology. , vol.143 , pp. 1851-1857
    • Abad, V.1    Meyers, J.L.2    Weise, M.3    et al4
  • 4
    • 0023130144 scopus 로고
    • Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth
    • Hunziker EB, Schenk RK, Cruz-Orive LM. Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth. J Bone Joint Surg Am. 1987, 69:162-73.
    • (1987) J Bone Joint Surg Am. , vol.69 , pp. 162-173
    • Hunziker, E.B.1    Schenk, R.K.2    Cruz-Orive, L.M.3
  • 5
    • 0030483252 scopus 로고    scopus 로고
    • Differential growth by growth plates as a function of multiple parameters of chondrocytic kinetics
    • Wilsman NJ, Farnum CE, Leiferman EM. Differential growth by growth plates as a function of multiple parameters of chondrocytic kinetics. J Orthop Res. 1996, 14:927-36.
    • (1996) J Orthop Res. , vol.14 , pp. 927-936
    • Wilsman, N.J.1    Farnum, C.E.2    Leiferman, E.M.3    et al4
  • 6
    • 10044261918 scopus 로고    scopus 로고
    • Cell-cycle control and the cartilage growth plate
    • Beier F. Cell-cycle control and the cartilage growth plate. J Cell Physiol. 2005, 202:1-8.
    • (2005) J Cell Physiol. , vol.202 , pp. 1-8
    • Beier, F.1
  • 7
    • 0026153593 scopus 로고
    • Linear relationship between the volume of hypertrophic chondrocytes and the rate of longitudinal bone growth in growth plates
    • Breur GJ, VanEnkevort BA, Farnum CE. Linear relationship between the volume of hypertrophic chondrocytes and the rate of longitudinal bone growth in growth plates. J Orthop Res. 1991, 9:348-59.
    • (1991) J Orthop Res. , vol.9 , pp. 348-359
    • Breur, G.J.1    VanEnkevort, B.A.2    Farnum, C.E.3    et al4
  • 8
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • Karsenty G, Wagner EF. Reaching a genetic and molecular understanding of skeletal development. Dev Cell. 2002, 2:389-406.
    • (2002) Dev Cell. , vol.2 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 9
    • 0036019912 scopus 로고    scopus 로고
    • Chondrodysplasias due to proteoglycan defects
    • Schwartz NB, Domowicz M. Chondrodysplasias due to proteoglycan defects. Glycobiology. 2002, 12:57-68.
    • (2002) Glycobiology. , vol.12 , pp. 57-68
    • Schwartz, N.B.1    Domowicz, M.2
  • 10
    • 0028157152 scopus 로고
    • The type II collagenopathies: a spectrum of chondrodysplasias
    • Spranger J, Winterpacht A, Zabel B. The type II collagenopathies: a spectrum of chondrodysplasias. Eur J Pediatr. 1994, 153:56-65.
    • (1994) Eur J Pediatr. , vol.153 , pp. 56-65
    • Spranger, J.1    Winterpacht, A.2    Zabel, B.3
  • 11
    • 16244421736 scopus 로고    scopus 로고
    • Transcriptional regulation of chondrocyte maturation: potential involvement of transcription factors in OA pathogenesis
    • Drissi H, Zuscik M, Rosier R. Transcriptional regulation of chondrocyte maturation: potential involvement of transcription factors in OA pathogenesis. Mol Aspects Med. 2005, 26:169-79.
    • (2005) Mol Aspects Med. , vol.26 , pp. 169-179
    • Drissi, H.1    Zuscik, M.2    Rosier, R.3    et al4
  • 12
    • 33847234252 scopus 로고    scopus 로고
    • Growth plate cartilage as developmental model in osteoarthritis reserach-potentials and limitations
    • Aigner T, Gerwin N. Growth plate cartilage as developmental model in osteoarthritis reserach-potentials and limitations. Curr Drug Targets. 2007, 8:377-85.
    • (2007) Curr Drug Targets. , vol.8 , pp. 377-385
    • Aigner, T.1    Gerwin, N.2
  • 13
    • 27644453166 scopus 로고    scopus 로고
    • Microarray analyses of gene expression during chondrocyte differentiation identifies novel regulators of hypertrophy
    • James CG, Appleton CT, Ulici V. Microarray analyses of gene expression during chondrocyte differentiation identifies novel regulators of hypertrophy. Mol Biol Cell. 2005, 16:5316-33.
    • (2005) Mol Biol Cell. , vol.16 , pp. 5316-5333
    • James, C.G.1    Appleton, C.T.2    Ulici, V.3    et al4
  • 14
    • 15744375543 scopus 로고    scopus 로고
    • RhoA/ROCK signaling regulates Sox9 expression and actin organization during chondrogenesis
    • Woods A, Wang G, Beier F. RhoA/ROCK signaling regulates Sox9 expression and actin organization during chondrogenesis. J Biol Chem. 2005, 280:11626-34.
    • (2005) J Biol Chem. , vol.280 , pp. 11626-11634
    • Woods, A.1    Wang, G.2    Beier, F.3
  • 15
    • 33744956176 scopus 로고    scopus 로고
    • RhoA/ROCK signaling regulates chondrogenesis in a context-dependent manner
    • Woods A, Beier F. RhoA/ROCK signaling regulates chondrogenesis in a context-dependent manner. J Biol Chem. 2006, 281:13134-40.
    • (2006) J Biol Chem. , vol.281 , pp. 13134-13140
    • Woods, A.1    Beier, F.2
  • 16
    • 1842581698 scopus 로고    scopus 로고
    • RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation
    • Wang G, Woods A, Sabari S. RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation. J Biol Chem. 2004, 279:13205-14.
    • (2004) J Biol Chem. , vol.279 , pp. 13205-13214
    • Wang, G.1    Woods, A.2    Sabari, S.3    et al4
  • 17
    • 0023902202 scopus 로고
    • Microfilament modification by dihydrocytochalasin B causes retinoid acid-modulated chondrocytes to re-express the differentiated collagen phenotype without a change in shape
    • Benya PD, Brown PD, Padilla SR. Microfilament modification by dihydrocytochalasin B causes retinoid acid-modulated chondrocytes to re-express the differentiated collagen phenotype without a change in shape. J Cell Biol. 1988, 106:161-70.
    • (1988) J Cell Biol. , vol.106 , pp. 161-170
    • Benya, P.D.1    Brown, P.D.2    Padilla, S.R.3
  • 18
    • 0023931326 scopus 로고
    • Alterations in chondrocyte cytoskeletal architecture during phenotypic modulation by retinoic acid and dihydrocytochalasin B-induced reexpression
    • Brown PD, Benya PD. Alterations in chondrocyte cytoskeletal architecture during phenotypic modulation by retinoic acid and dihydrocytochalasin B-induced reexpression. J Cell Biol. 1988, 106:171-9.
    • (1988) J Cell Biol. , vol.106 , pp. 171-179
    • Brown, P.D.1    Benya, P.D.2
  • 19
    • 0024254826 scopus 로고
    • Modulation and re-expression of the chondrocyte phenotype; mediation by cell shape and microfilament modification
    • Benya PD. Modulation and re-expression of the chondrocyte phenotype; mediation by cell shape and microfilament modification. Pathol Immunopathol Res. 1988, 7:51-4.
    • (1988) Pathol Immunopathol Res. , vol.7 , pp. 51-54
    • Benya, P.D.1
  • 20
    • 0023746647 scopus 로고
    • Influence of cytochalasin D induced changes in cell shape on proteoglycan sythesis by cultured articular chondrocytes
    • Newman SA, Watt FM. Influence of cytochalasin D induced changes in cell shape on proteoglycan sythesis by cultured articular chondrocytes. Exp Cell Res. 1988, 178:199-210.
    • (1988) Exp Cell Res. , vol.178 , pp. 199-210
    • Newman, S.A.1    Watt, F.M.2
  • 21
    • 0029122355 scopus 로고
    • Cytochalasin D induces changes in cell shape and promotes in vitro chondrogenesis: a morphological study
    • Loty S, Forest N, Boulekbache H. Cytochalasin D induces changes in cell shape and promotes in vitro chondrogenesis: a morphological study. Biol Cell. 1995, 83:149-61.
    • (1995) Biol Cell. , vol.83 , pp. 149-161
    • Loty, S.1    Forest, N.2    Boulekbache, H.3    et al4
  • 22
    • 34047199291 scopus 로고    scopus 로고
    • C-type natriuretic peptide regulates endochondral bone growth through p38 MAP kinase-dependent and independent pathways
    • Agoston H, Khan S, James CG. C-type natriuretic peptide regulates endochondral bone growth through p38 MAP kinase-dependent and independent pathways. BMC Devl Biol 2007, 7:18.
    • (2007) BMC Devl Biol , vol.7 , pp. 18
    • Agoston, H.1    Khan, S.2    James, C.G.3    et al4
  • 23
    • 42549158610 scopus 로고    scopus 로고
    • The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation
    • Ulici V, Hoenselaar KD, Gillespie JR. The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation. BMC Dev Biol 2008, 11:40.
    • (2008) BMC Dev Biol , vol.11 , pp. 40
    • Ulici, V.1    Hoenselaar, K.D.2    Gillespie, J.R.3    et al4
  • 24
    • 34249899968 scopus 로고    scopus 로고
    • Genetic ablation of Rac1 in cartilage results in chondrodysplasia
    • Wang G, Woods A, Agoston H. Genetic ablation of Rac1 in cartilage results in chondrodysplasia. Dev Biol. 2007, 306:612-23.
    • (2007) Dev Biol. , vol.306 , pp. 612-623
    • Wang, G.1    Woods, A.2    Agoston, H.3    et al4
  • 25
    • 34547119052 scopus 로고    scopus 로고
    • Expression profiling of dexamethasone treated primary chondrocyte identifies targets of glucocorticoid signaling in endochondral ossification development
    • James CG, Ulici V, Tuckermann J. Expression profiling of dexamethasone treated primary chondrocyte identifies targets of glucocorticoid signaling in endochondral ossification development. BMC Genomics 2007, 8:205.
    • (2007) BMC Genomics , vol.8 , pp. 205
    • James, C.G.1    Ulici, V.2    Tuckermann, J.3    et al4
  • 26
    • 35548949049 scopus 로고    scopus 로고
    • Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism
    • Kang HS, Angers M, Beak JY. Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism. Physiol Genomics. 2007, 31:281-94.
    • (2007) Physiol Genomics. , vol.31 , pp. 281-294
    • Kang, H.S.1    Angers, M.2    Beak, J.Y.3    et al4
  • 27
    • 33749548543 scopus 로고    scopus 로고
    • The transcription factor ATF3 is upregulated during chondrocyte differentiation and represses cyclin D1 and A gene transcription
    • James CG, Woods A, Underhill TM. The transcription factor ATF3 is upregulated during chondrocyte differentiation and represses cyclin D1 and A gene transcription. BMC Mol Biol 2006, 7:30.
    • (2006) BMC Mol Biol , vol.7 , pp. 30
    • James, C.G.1    Woods, A.2    Underhill, T.M.3    et al4
  • 29
    • 0028244823 scopus 로고
    • Jasplakinolide, a cytotoxic natural product, induces actin polyerization and competitively inhibits the binding of phalloidin to F-actin
    • Bubb M, Senderowicz A, Sausville E. Jasplakinolide, a cytotoxic natural product, induces actin polyerization and competitively inhibits the binding of phalloidin to F-actin. J Biol Chem. 1994, 269:14869-71.
    • (1994) J Biol Chem. , vol.269 , pp. 14869-14871
    • Bubb, M.1    Senderowicz, A.2    Sausville, E.3    et al4
  • 30
    • 0022994966 scopus 로고
    • The kinetics of cytochalasin D binding to monomeric actin
    • Goddette DW, Frieden C. The kinetics of cytochalasin D binding to monomeric actin. J Biol Chem. 1986, 261:15970-3.
    • (1986) J Biol Chem. , vol.261 , pp. 15970-15973
    • Goddette, D.W.1    Frieden, C.2
  • 31
    • 0038737042 scopus 로고    scopus 로고
    • Actin dynamics control SRF activity by regulation of its coactivator MAL
    • Miralles F, Posern G, Zaromytidou A-I. Actin dynamics control SRF activity by regulation of its coactivator MAL. Cell. 2003, 113:329-42.
    • (2003) Cell. , vol.113 , pp. 329-342
    • Miralles, F.1    Posern, G.2    Zaromytidou, A.-I.3    et al4
  • 32
    • 48449104742 scopus 로고    scopus 로고
    • Babelomics: advanced functional profiling of transcriptomics, proteomics and genomics experiments
    • Al-Shahrour F, Carbonell J, Minquez P. Babelomics: advanced functional profiling of transcriptomics, proteomics and genomics experiments. Nucleic Acids Res. 2008, 36:W341-6.
    • (2008) Nucleic Acids Res. , vol.36
    • Al-Shahrour, F.1    Carbonell, J.2    Minquez, P.3    et al4
  • 33
    • 24344482842 scopus 로고    scopus 로고
    • Expression and activation of peroxisome proliferator-activated receptors in growth plate chondrocytes
    • Shao YY, Wang L, Hicks DG. Expression and activation of peroxisome proliferator-activated receptors in growth plate chondrocytes. J Orthop Res. 2005, 23:1139-45.
    • (2005) J Orthop Res. , vol.23 , pp. 1139-1145
    • Shao, Y.Y.1    Wang, L.2    Hicks, D.G.3    et al4
  • 34
    • 17844363974 scopus 로고    scopus 로고
    • Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes
    • Hill TP, Spater D, Taketo MM. Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell. 2005, 8:727-38.
    • (2005) Dev Cell. , vol.8 , pp. 727-738
    • Hill, T.P.1    Spater, D.2    Taketo, M.M.3    et al4
  • 35
  • 36
    • 77951964731 scopus 로고    scopus 로고
    • PPARgamma2 expression in growth plate chondrocytes is regulated by p38 and GSK-3
    • DOI
    • Stanton LA, Beier F. PPARgamma2 expression in growth plate chondrocytes is regulated by p38 and GSK-3. J Cell Mol Med 10.1111/j.1582-4934.2008.00396.x, DOI
    • J Cell Mol Med
    • Stanton, L.A.1    Beier, F.2
  • 37
    • 18744391368 scopus 로고    scopus 로고
    • The Wnt antagonist Frzb-1 regulates chondrocyte maturation and long bone development during limb skeletogenesis
    • Enomoto-Iwamoto M, Kitagawa J, Koyama E. The Wnt antagonist Frzb-1 regulates chondrocyte maturation and long bone development during limb skeletogenesis. Dev Biol. 2002, 251:142-56.
    • (2002) Dev Biol. , vol.251 , pp. 142-156
    • Enomoto-Iwamoto, M.1    Kitagawa, J.2    Koyama, E.3    et al4
  • 38
    • 0043208998 scopus 로고    scopus 로고
    • Functional role of growth/differentiation factor 5 in chondrogenesis of limb mesenchymal cells
    • Coleman CM, Tuan RS. Functional role of growth/differentiation factor 5 in chondrogenesis of limb mesenchymal cells. Mech Dev. 2003, 120:823-36.
    • (2003) Mech Dev. , vol.120 , pp. 823-836
    • Coleman, C.M.1    Tuan, R.S.2
  • 39
    • 0029119066 scopus 로고
    • Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3
    • Cunningham NS, Jenkins NA, Gilbert DJ. Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3. Growth Factors. 1995, 12:99-109.
    • (1995) Growth Factors. , vol.12 , pp. 99-109
    • Cunningham, N.S.1    Jenkins, N.A.2    Gilbert, D.J.3    et al4
  • 40
    • 0035499204 scopus 로고    scopus 로고
    • Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival
    • Schipani E, Ryan HE, Didrickson S. Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Genes Dev. 2001, 15:2865-76.
    • (2001) Genes Dev. , vol.15 , pp. 2865-2876
    • Schipani, E.1    Ryan, H.E.2    Didrickson, S.3    et al4
  • 41
    • 9444283789 scopus 로고    scopus 로고
    • The gene encoding human retinoic acid-receptor-related orphan receptor alpha is a target for hypoxia-inducible factor 1
    • Chauvet C, Bois-Joyeux B, Berra E. The gene encoding human retinoic acid-receptor-related orphan receptor alpha is a target for hypoxia-inducible factor 1. Biochem J. 2004, 384:79-85.
    • (2004) Biochem J. , vol.384 , pp. 79-85
    • Chauvet, C.1    Bois-Joyeux, B.2    Berra, E.3    et al4
  • 42
    • 1842848068 scopus 로고    scopus 로고
    • X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha
    • Kallen JA, Schlaeppi JM, Bitsch F. X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha. Structure. 2002, 10:1697-707.
    • (2002) Structure. , vol.10 , pp. 1697-1707
    • Kallen, J.A.1    Schlaeppi, J.M.2    Bitsch, F.3    et al4
  • 43
    • 0028920392 scopus 로고
    • Transcriptional activation of the nuclear receptor RZR alpha by the pineal gland hormone melatonin and identification of CGP 52608 as a synthetic ligand
    • Wiesenberg I, Missbach M, Kahlen JP. Transcriptional activation of the nuclear receptor RZR alpha by the pineal gland hormone melatonin and identification of CGP 52608 as a synthetic ligand. Nucleic Acids Res. 1995, 23:327-33.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 327-333
    • Wiesenberg, I.1    Missbach, M.2    Kahlen, J.P.3    et al4
  • 44
    • 0018939225 scopus 로고
    • Mevinolin: A highly potent competitve inhibitor of hydroxymethylglutaryl coenzyme A reductase and a cholesterol-lowering agent
    • Alberts AW, Chen J, Kuron G. Mevinolin: A highly potent competitve inhibitor of hydroxymethylglutaryl coenzyme A reductase and a cholesterol-lowering agent. Proc Natl Acad Sci USA. 1980, 77:3957-61.
    • (1980) Proc Natl Acad Sci USA. , vol.77 , pp. 3957-3961
    • Alberts, A.W.1    Chen, J.2    Kuron, G.3    et al4
  • 45
    • 4344668155 scopus 로고    scopus 로고
    • RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR
    • Lau P, Nixon SJ, Parton RG. RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR. J Biol Chem. 2004, 279:36828-40.
    • (2004) J Biol Chem. , vol.279 , pp. 36828-36840
    • Lau, P.1    Nixon, S.J.2    Parton, R.G.3    et al4
  • 46
    • 0034045297 scopus 로고    scopus 로고
    • Expression of thrombospondin-1 and its receptor CD36 in human osteoarthritic cartilage
    • Pfander D, Cramer T, Deuerling D. Expression of thrombospondin-1 and its receptor CD36 in human osteoarthritic cartilage. Ann Rheum Dis. 2000, 59:448-54.
    • (2000) Ann Rheum Dis. , vol.59 , pp. 448-454
    • Pfander, D.1    Cramer, T.2    Deuerling, D.3    et al4
  • 47
    • 0342844267 scopus 로고    scopus 로고
    • RALDH3, a retinaldehyde dehydrogenase that generates retinoic acid, is expressed in the ventral retina, otic vesical and olfactory pit during mouse development
    • Mic FA, Molotkiv A, Fan X. RALDH3, a retinaldehyde dehydrogenase that generates retinoic acid, is expressed in the ventral retina, otic vesical and olfactory pit during mouse development. Mech Dev. 2000, 97:227-30.
    • (2000) Mech Dev. , vol.97 , pp. 227-230
    • Mic, F.A.1    Molotkiv, A.2    Fan, X.3    et al4
  • 48
    • 33947575572 scopus 로고    scopus 로고
    • Regulation of gluconeogenesis by Kruppel-like factor 15
    • Gray S, Wang B, Orihuela Y. Regulation of gluconeogenesis by Kruppel-like factor 15. Cell Metab. 2007, 5:305-12.
    • (2007) Cell Metab. , vol.5 , pp. 305-312
    • Gray, S.1    Wang, B.2    Orihuela, Y.3    et al4
  • 49
    • 0036151370 scopus 로고    scopus 로고
    • Dedifferentiation-associated changes in morphology and gene expression in primary human articular chondrocytes in cell culture
    • Schnabel M, Marlovits S, Eckhoff G. Dedifferentiation-associated changes in morphology and gene expression in primary human articular chondrocytes in cell culture. Osteoarthritis Cartilage. 2002, 10:62-70.
    • (2002) Osteoarthritis Cartilage. , vol.10 , pp. 62-70
    • Schnabel, M.1    Marlovits, S.2    Eckhoff, G.3    et al4
  • 50
    • 0026329259 scopus 로고
    • Proteoglycan and collagen synthesis are correlated with actin organization in dedifferentiating chondrocytes
    • Mallein-Gerin F, Garrone R, van der Rest M. Proteoglycan and collagen synthesis are correlated with actin organization in dedifferentiating chondrocytes. Eur J Cell Biol. 1991, 56:364-73.
    • (1991) Eur J Cell Biol. , vol.56 , pp. 364-373
    • Mallein-Gerin, F.1    Garrone, R.2    van der Rest, M.3
  • 51
    • 34548489858 scopus 로고    scopus 로고
    • Regulation of chondrocyte differentiation by the actin cytoskeleton and adhesive interactions
    • Woods A, Wang G, Beier F. Regulation of chondrocyte differentiation by the actin cytoskeleton and adhesive interactions. J Cell Physiol. 2007, 213:1-8.
    • (2007) J Cell Physiol. , vol.213 , pp. 1-8
    • Woods, A.1    Wang, G.2    Beier, F.3
  • 52
    • 56649088324 scopus 로고    scopus 로고
    • A review of actin binding proteins: new perspectives
    • Uribe R, Jay D. A review of actin binding proteins: new perspectives. Mol Biol Rep. 2009, 36:121-5.
    • (2009) Mol Biol Rep. , vol.36 , pp. 121-125
    • Uribe, R.1    Jay, D.2
  • 53
    • 0037447060 scopus 로고    scopus 로고
    • Filamin-A fragment localizes to the nucleus to regulate androgen receptor and coactivator functions
    • Loy CJ, Sim KS, Yong EL. Filamin-A fragment localizes to the nucleus to regulate androgen receptor and coactivator functions. Proc Natl Acad Sci USA. 2003, 100:4562-7.
    • (2003) Proc Natl Acad Sci USA. , vol.100 , pp. 4562-4567
    • Loy, C.J.1    Sim, K.S.2    Yong, E.L.3
  • 54
    • 0033027858 scopus 로고    scopus 로고
    • VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
    • Gerber HP, Vu TH, Ryan AM. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med. 1999, 5:623-8.
    • (1999) Nat Med. , vol.5 , pp. 623-628
    • Gerber, H.P.1    Vu, T.H.2    Ryan, A.M.3    et al4
  • 55
    • 0032519518 scopus 로고    scopus 로고
    • Chondradherin expression changes in skeletal development
    • Shen Z, Gantcheva S, Mansson B. Chondradherin expression changes in skeletal development. Biochem J. 1998, 330:549-57.
    • (1998) Biochem J. , vol.330 , pp. 549-557
    • Shen, Z.1    Gantcheva, S.2    Mansson, B.3    et al4
  • 56
    • 43049121285 scopus 로고    scopus 로고
    • Collagen IX-deficiency seriously compromises growth cartilage development in mice
    • Dreier R, Opolka A, Grifka J. Collagen IX-deficiency seriously compromises growth cartilage development in mice. Matrix Biol. 2008, 27:319-29.
    • (2008) Matrix Biol. , vol.27 , pp. 319-329
    • Dreier, R.1    Opolka, A.2    Grifka, J.3    et al4
  • 57
    • 45549097592 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases during vascularization and ossification of normal and impaired avian growth plate
    • Hasky-Negev M, Simsa S, Tong A. Expression of matrix metalloproteinases during vascularization and ossification of normal and impaired avian growth plate. J Anim Sci. 2008, 86:1306-15.
    • (2008) J Anim Sci. , vol.86 , pp. 1306-1315
    • Hasky-Negev, M.1    Simsa, S.2    Tong, A.3    et al4
  • 58
    • 13144256685 scopus 로고    scopus 로고
    • Staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice
    • Steinmayr M, Andre E, Conquet F. Staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice. Proc Natl Acad Sci USA. 1998, 95:3960-5.
    • (1998) Proc Natl Acad Sci USA. , vol.95 , pp. 3960-3965
    • Steinmayr, M.1    Andre, E.2    Conquet, F.3    et al4
  • 59
    • 0035951788 scopus 로고    scopus 로고
    • Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha
    • Raspe E, Duez H, Gervois P. Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha. J Biol Chem. 2001, 276:2865-71.
    • (2001) J Biol Chem. , vol.276 , pp. 2865-2871
    • Raspe, E.1    Duez, H.2    Gervois, P.3    et al4
  • 60
    • 0034254930 scopus 로고    scopus 로고
    • In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism
    • Meyer T, Kneissel M, Mariani J. In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism. Proc Natl Acad Sci USA. 2000, 97:9197-202.
    • (2000) Proc Natl Acad Sci USA. , vol.97 , pp. 9197-9202
    • Meyer, T.1    Kneissel, M.2    Mariani, J.3    et al4
  • 61
    • 0026512596 scopus 로고
    • Evidence for a hyperexcitability state of staggerer mutant mice macrophages
    • Kopmels B, Mariani J, Delhaye-Bouchaud N. Evidence for a hyperexcitability state of staggerer mutant mice macrophages. J Neurochem. 1992, 58:192-9.
    • (1992) J Neurochem. , vol.58 , pp. 192-199
    • Kopmels, B.1    Mariani, J.2    Delhaye-Bouchaud, N.3    et al4
  • 62
    • 19044390915 scopus 로고    scopus 로고
    • Rac1/Cdc42 and RhoA GTPases antagonistically regulate chondrocyte proliferation, hypertrophy, and apoptosis
    • Wang G, Beier F. Rac1/Cdc42 and RhoA GTPases antagonistically regulate chondrocyte proliferation, hypertrophy, and apoptosis. J Bone Miner Res. 2005, 20:1022-31.
    • (2005) J Bone Miner Res. , vol.20 , pp. 1022-1031
    • Wang, G.1    Beier, F.2
  • 63
    • 0031970317 scopus 로고    scopus 로고
    • Membrane association and targeting of prenylated Ras-like GTPases
    • Seabra MC. Membrane association and targeting of prenylated Ras-like GTPases. Cell Signal. 1998, 10:167-72.
    • (1998) Cell Signal. , vol.10 , pp. 167-172
    • Seabra, M.C.1
  • 64
    • 0001152108 scopus 로고
    • Staggerer, a new mutation in the mouse affecting the cerebellum
    • Sidman RL, Lane PW, Dickie MM. Staggerer, a new mutation in the mouse affecting the cerebellum. Science. 1962, 137:610-2.
    • (1962) Science. , vol.137 , pp. 610-612
    • Sidman, R.L.1    Lane, P.W.2    Dickie, M.M.3
  • 65
    • 1042266622 scopus 로고    scopus 로고
    • Role of cholesterol in the regulation of growth plate chondrogenesis and longitudinal bone growth
    • Wu S, De Luca F. Role of cholesterol in the regulation of growth plate chondrogenesis and longitudinal bone growth. J Biol Chem. 2004, 279:4642-7.
    • (2004) J Biol Chem. , vol.279 , pp. 4642-4647
    • Wu, S.1    De Luca, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.