메뉴 건너뛰기




Volumn 175, Issue 4, 2009, Pages 1442-1452

Kindlin-1 is required for RhoGTPase-mediated lamellipodia formation in keratinocytes

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTININ; BETA1 INTEGRIN; COFILIN; FOCAL ADHESION KINASE; INTEGRIN; KINDLIN 1; LIM KINASE; P21 ACTIVATED KINASE 1; PROTEIN CDC42; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 73549105028     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2009.090203     Document Type: Article
Times cited : (69)

References (51)
  • 1
    • 57049169143 scopus 로고    scopus 로고
    • Kindlins: Essential regulators of integrin signalling and cell-matrix adhesion
    • Larjava H, Plow EF, Wu C: Kindlins: essential regulators of integrin signalling and cell-matrix adhesion. EMBO Rep 2008, 9:1203-1208
    • (2008) EMBO Rep , vol.9 , pp. 1203-1208
    • Larjava, H.1    Plow, E.F.2    Wu, C.3
  • 2
    • 40449133970 scopus 로고    scopus 로고
    • Kindlin-3 is essential for integrin activation and platelet aggregation
    • Moser M, Nieswandt B, Ussar S, Pozgajova M, Fassler R: Kindlin-3 is essential for integrin activation and platelet aggregation. Nat Med 2008, 14:325-330
    • (2008) Nat Med , vol.14 , pp. 325-330
    • Moser, M.1    Nieswandt, B.2    Ussar, S.3    Pozgajova, M.4    Fassler, R.5
  • 4
    • 43149085289 scopus 로고    scopus 로고
    • Ma YQ, Qin J, Wu C, Plow EF: Kindlin-2 (Mig-2): a co-activator of beta3 integrins. J Cell Biol 2008, 181:439-446
    • Ma YQ, Qin J, Wu C, Plow EF: Kindlin-2 (Mig-2): a co-activator of beta3 integrins. J Cell Biol 2008, 181:439-446
  • 5
    • 33747877557 scopus 로고    scopus 로고
    • The Kindlins: Subcellular localization and expression during murine development
    • Ussar S, Wang HV, Linder S, Fassler R, Moser M: The Kindlins: subcellular localization and expression during murine development. Exp Cell Res 2006, 312:3142-3151
    • (2006) Exp Cell Res , vol.312 , pp. 3142-3151
    • Ussar, S.1    Wang, H.V.2    Linder, S.3    Fassler, R.4    Moser, M.5
  • 6
    • 33845990287 scopus 로고    scopus 로고
    • Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytes
    • Herz C, Aumailley M, Schulte C, Schlotzer-Schrehardt U, Bruckner-Tuderman L, Has C: Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytes. J Biol Chem 2006, 281:36082-36090
    • (2006) J Biol Chem , vol.281 , pp. 36082-36090
    • Herz, C.1    Aumailley, M.2    Schulte, C.3    Schlotzer-Schrehardt, U.4    Bruckner-Tuderman, L.5    Has, C.6
  • 7
    • 66549121768 scopus 로고    scopus 로고
    • Kuijpers TW, van de Vijver E, Weterman MA, de Boer M, Tool AT, van den Berg TK, Moser M, Jakobs ME, Seeger K, Sanal O, Unal S, Cetin M, Roos D, Verhoeven AJ, Baas F: LAD-1/variant syndrome is caused by mutations in FERMT3. Blood 2009, 113:4740-4746
    • Kuijpers TW, van de Vijver E, Weterman MA, de Boer M, Tool AT, van den Berg TK, Moser M, Jakobs ME, Seeger K, Sanal O, Unal S, Cetin M, Roos D, Verhoeven AJ, Baas F: LAD-1/variant syndrome is caused by mutations in FERMT3. Blood 2009, 113:4740-4746
  • 8
    • 58149154658 scopus 로고    scopus 로고
    • Ussar S, Moser M, Widmaier M, Rognoni E, Harrer C, Genzel-Boroviczeny O, Fassler R: Loss of kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction, PLoS Genet 2008, 4:e1000289
    • Ussar S, Moser M, Widmaier M, Rognoni E, Harrer C, Genzel-Boroviczeny O, Fassler R: Loss of kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction, PLoS Genet 2008, 4:e1000289
  • 9
    • 49549083034 scopus 로고    scopus 로고
    • Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome
    • Lai-Cheong JE, Ussar S, Arita K, Hart IR, McGrath JA: Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome. J Invest Dermatol 2008, 128:2156-2165
    • (2008) J Invest Dermatol , vol.128 , pp. 2156-2165
    • Lai-Cheong, J.E.1    Ussar, S.2    Arita, K.3    Hart, I.R.4    McGrath, J.A.5
  • 14
    • 33751161054 scopus 로고    scopus 로고
    • Molecular and diagnostic aspects of genetic skin fragility
    • Has C, Bruckner-Tuderman L: Molecular and diagnostic aspects of genetic skin fragility. J Dermatol Sci 2006, 44:129-144
    • (2006) J Dermatol Sci , vol.44 , pp. 129-144
    • Has, C.1    Bruckner-Tuderman, L.2
  • 18
    • 0042196118 scopus 로고    scopus 로고
    • A role for alphabeta1 integrins in focal adhesion function and polarized cytoskeletal dynamics
    • Raghavan S, Vaezi A, Fuchs E: A role for alphabeta1 integrins in focal adhesion function and polarized cytoskeletal dynamics. Dev Cell 2003, 5:415-427
    • (2003) Dev Cell , vol.5 , pp. 415-427
    • Raghavan, S.1    Vaezi, A.2    Fuchs, E.3
  • 19
    • 1342346591 scopus 로고    scopus 로고
    • The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion
    • Kloeker S, Major MB, Calderwood DA, Ginsberg MH, Jones DA, Beckerle MC: The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion. J Biol Chem 2004, 279:6824-6833
    • (2004) J Biol Chem , vol.279 , pp. 6824-6833
    • Kloeker, S.1    Major, M.B.2    Calderwood, D.A.3    Ginsberg, M.H.4    Jones, D.A.5    Beckerle, M.C.6
  • 20
    • 42049092972 scopus 로고    scopus 로고
    • Regulation of actin assembly associated with protrusion and adhesion in cell migration
    • Le Clainche C, Carlier MF: Regulation of actin assembly associated with protrusion and adhesion in cell migration. Physiol Rev 2008, 88:489-513
    • (2008) Physiol Rev , vol.88 , pp. 489-513
    • Le Clainche, C.1    Carlier, M.F.2
  • 21
    • 27844604200 scopus 로고    scopus 로고
    • Pases and the control of cell behaviour
    • Hall A: Rho GT: Pases and the control of cell behaviour. Biochem Soc Trans 2005, 33:891-895
    • (2005) Biochem Soc Trans , vol.33 , pp. 891-895
    • Hall, A.1    Rho, G.T.2
  • 22
    • 0034755942 scopus 로고    scopus 로고
    • Molecular complexity and dynamics of cell-matrix adhesions
    • Zamir E, Geiger B: Molecular complexity and dynamics of cell-matrix adhesions. J Cell Sci 2001, 114:3583-3590
    • (2001) J Cell Sci , vol.114 , pp. 3583-3590
    • Zamir, E.1    Geiger, B.2
  • 23
    • 33746800269 scopus 로고    scopus 로고
    • Focal adhesions: What's new inside
    • Lo SH: Focal adhesions: what's new inside. Dev Biol 2006, 294:280-291
    • (2006) Dev Biol , vol.294 , pp. 280-291
    • Lo, S.H.1
  • 25
    • 0035516140 scopus 로고    scopus 로고
    • Transmembrane crosstalk between the extracellular matrix- cytoskeleton crosstalk
    • Geiger B, Bershadsky A, Pankov R, Yamada KM: Transmembrane crosstalk between the extracellular matrix- cytoskeleton crosstalk. Nat Rev Mol Cell Biol 2001, 2:793-805
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 793-805
    • Geiger, B.1    Bershadsky, A.2    Pankov, R.3    Yamada, K.M.4
  • 27
    • 0023890291 scopus 로고
    • Characterization of primary human keratinocytes transformed by human papillomavirus type 18
    • Kaur P, McDougall JK: Characterization of primary human keratinocytes transformed by human papillomavirus type 18. J Virol 1988, 62:1917-1924
    • (1988) J Virol , vol.62 , pp. 1917-1924
    • Kaur, P.1    McDougall, J.K.2
  • 28
    • 0032476013 scopus 로고    scopus 로고
    • Two forms of collagen XVII in keratinocytes: A full-length transmembrane protein and a soluble ectodomain
    • Schacke H, Schumann H, Hammami-Hauasli N, Raghunath M, Bruckner-Tuderman L: Two forms of collagen XVII in keratinocytes: a full-length transmembrane protein and a soluble ectodomain. J Biol Chem 1998, 273:25937-25943
    • (1998) J Biol Chem , vol.273 , pp. 25937-25943
    • Schacke, H.1    Schumann, H.2    Hammami-Hauasli, N.3    Raghunath, M.4    Bruckner-Tuderman, L.5
  • 29
    • 0025338007 scopus 로고
    • Developmental changes in expression of contractile and cytoskeletal proteins in human aortic smooth muscle
    • Glukhova MA, Frid MG, Koteliansky VE: Developmental changes in expression of contractile and cytoskeletal proteins in human aortic smooth muscle. J Biol Chem 1990, 265:13042-13046
    • (1990) J Biol Chem , vol.265 , pp. 13042-13046
    • Glukhova, M.A.1    Frid, M.G.2    Koteliansky, V.E.3
  • 30
    • 0026629850 scopus 로고
    • The dermalepidermal junction of human skin contains a novel laminin variant
    • Marinkovich MP, Lunstrum GP, Keene DR, Burgeson RE: The dermalepidermal junction of human skin contains a novel laminin variant. J Cell Biol 1992, 119:695-703
    • (1992) J Cell Biol , vol.119 , pp. 695-703
    • Marinkovich, M.P.1    Lunstrum, G.P.2    Keene, D.R.3    Burgeson, R.E.4
  • 32
    • 2342431917 scopus 로고    scopus 로고
    • Laminin 5 deposition regulates keratinocyte polarization and persistent migration
    • Frank DE, Carter WG: Laminin 5 deposition regulates keratinocyte polarization and persistent migration. J Cell Sci 2004, 117:1351-1363
    • (2004) J Cell Sci , vol.117 , pp. 1351-1363
    • Frank, D.E.1    Carter, W.G.2
  • 34
    • 66449119343 scopus 로고    scopus 로고
    • Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects
    • Harburger DS, Bouaouina M, Calderwood DA: Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects. J Biol Chem 2009, 284:11485-11497
    • (2009) J Biol Chem , vol.284 , pp. 11485-11497
    • Harburger, D.S.1    Bouaouina, M.2    Calderwood, D.A.3
  • 37
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • Jaffe AB, Hall A: Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 2005, 21:247-269
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 38
    • 4444361792 scopus 로고    scopus 로고
    • Integrin alpha3beta1 directs the stabilization of a polarized lamellipodium in epithelial cells through activation of Rac1
    • Choma DP, Pumiglia K, DiPersio CM: Integrin alpha3beta1 directs the stabilization of a polarized lamellipodium in epithelial cells through activation of Rac1. J Cell Sci 2004, 117:3947-3959
    • (2004) J Cell Sci , vol.117 , pp. 3947-3959
    • Choma, D.P.1    Pumiglia, K.2    DiPersio, C.M.3
  • 39
    • 33845736815 scopus 로고    scopus 로고
    • Integrin alpha3beta1-dependent activation of FAK/Src regulates Rac1-mediated keratinocyte polarization on laminin-5
    • Choma DP, Milano V, Pumiglia KM, DiPersio CM: Integrin alpha3beta1-dependent activation of FAK/Src regulates Rac1-mediated keratinocyte polarization on laminin-5. J Invest Dermatol 2007, 127:31-40
    • (2007) J Invest Dermatol , vol.127 , pp. 31-40
    • Choma, D.P.1    Milano, V.2    Pumiglia, K.M.3    DiPersio, C.M.4
  • 40
    • 23244452354 scopus 로고    scopus 로고
    • Stem cell depletion through epidermal deletion of Rac1
    • Benitah SA, Frye M, Glogauer M, Watt FM: Stem cell depletion through epidermal deletion of Rac1. Science 2005, 309:933-935
    • (2005) Science , vol.309 , pp. 933-935
    • Benitah, S.A.1    Frye, M.2    Glogauer, M.3    Watt, F.M.4
  • 41
    • 25444486668 scopus 로고    scopus 로고
    • The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex
    • Mertens AE, Rygiel TP, Olivo C, van der Kammen R, Collard JG: The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex. J Cell Biol 2005, 170:1029-1037
    • (2005) J Cell Biol , vol.170 , pp. 1029-1037
    • Mertens, A.E.1    Rygiel, T.P.2    Olivo, C.3    van der Kammen, R.4    Collard, J.G.5
  • 44
    • 33750979813 scopus 로고    scopus 로고
    • Cdc42 expression in keratinocytes is required for the maintenance of the basement membrane in skin
    • Wu X, Quondamatteo F, Brakebusch C: Cdc42 expression in keratinocytes is required for the maintenance of the basement membrane in skin. Matrix Biol 2006, 25:466-474
    • (2006) Matrix Biol , vol.25 , pp. 466-474
    • Wu, X.1    Quondamatteo, F.2    Brakebusch, C.3
  • 45
  • 48
    • 0035171699 scopus 로고    scopus 로고
    • Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation
    • Toshima J, Toshima JY, Amano T, Yang N, Narumiya S, Mizuno K: Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation. Mol Biol Cell 2001, 12:1131-1145
    • (2001) Mol Biol Cell , vol.12 , pp. 1131-1145
    • Toshima, J.1    Toshima, J.Y.2    Amano, T.3    Yang, N.4    Narumiya, S.5    Mizuno, K.6
  • 49
    • 0030968177 scopus 로고    scopus 로고
    • The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts
    • Braga VM, Machesky LM, Hall A, Hotchin NA: The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J Cell Biol 1997, 137:1421-1431
    • (1997) J Cell Biol , vol.137 , pp. 1421-1431
    • Braga, V.M.1    Machesky, L.M.2    Hall, A.3    Hotchin, N.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.