메뉴 건너뛰기




Volumn 18, Issue 2, 2008, Pages 206-213

Quantitative systems-level determinants of human genes targeted by successful drugs

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 39049153521     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.6888208     Document Type: Article
Times cited : (71)

References (31)
  • 1
    • 33645675960 scopus 로고    scopus 로고
    • Estimating the cost of new drug development: Is it really 802 million dollars?
    • Adams, C.P. and Brantner, V.V. 2006. Estimating the cost of new drug development: Is it really 802 million dollars? Health Aff. (Millwood) 25: 420-428.
    • (2006) Health Aff. (Millwood) , vol.25 , pp. 420-428
    • Adams, C.P.1    Brantner, V.V.2
  • 3
    • 0038513959 scopus 로고    scopus 로고
    • Scale-free networks
    • Barabasi, A.L. and Bonabeau, E. 2003. Scale-free networks. Sci. Am. 288: 60-69.
    • (2003) Sci. Am , vol.288 , pp. 60-69
    • Barabasi, A.L.1    Bonabeau, E.2
  • 5
    • 2942624159 scopus 로고    scopus 로고
    • Apparent dependence of protein evolutionary rate on number of interactions is linked to biases in protein-protein interactions data sets
    • doi: 10.1186/1471-2148-3-21
    • Bloom, J.D. and Adami, C. 2003. Apparent dependence of protein evolutionary rate on number of interactions is linked to biases in protein-protein interactions data sets. BMC Evol. Biol. 3: 21. doi: 10.1186/1471-2148-3-21.
    • (2003) BMC Evol. Biol , vol.3 , pp. 21
    • Bloom, J.D.1    Adami, C.2
  • 7
    • 0034677966 scopus 로고    scopus 로고
    • Drug discovery: A historical perspective
    • Drews, J. 2000. Drug discovery: A historical perspective. Science 287: 1960-1964.
    • (2000) Science , vol.287 , pp. 1960-1964
    • Drews, J.1
  • 8
    • 0037404094 scopus 로고    scopus 로고
    • Strategic trends in the drug industry
    • Drews, J. 2003. Strategic trends in the drug industry. Drug Discov. Today 8: 411-420.
    • (2003) Drug Discov. Today , vol.8 , pp. 411-420
    • Drews, J.1
  • 9
    • 33746628593 scopus 로고    scopus 로고
    • Case histories, magic bullets and the state of drug discovery
    • Drews, J. 2006. Case histories, magic bullets and the state of drug discovery. Nat. Rev. Drug Discov. 5: 635-640.
    • (2006) Nat. Rev. Drug Discov , vol.5 , pp. 635-640
    • Drews, J.1
  • 14
    • 0020083498 scopus 로고
    • The meaning and use of the area under a receiver operating characteristic (ROC) curve
    • Hanley, J.A. and McNeil, B.J. 1982. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 143: 29-36.
    • (1982) Radiology , vol.143 , pp. 29-36
    • Hanley, J.A.1    McNeil, B.J.2
  • 15
    • 41349104828 scopus 로고    scopus 로고
    • Growing scale-free networks with tunable clustering
    • doi: 10.1103/PhysRevE.65.026107
    • Holme, P. and Kim, B.J. 2002. Growing scale-free networks with tunable clustering. Phys. Rev. E Stat. Nonlin. Soft Matter Phys. 65: 026107. doi: 10.1103/PhysRevE.65.026107.
    • (2002) Phys. Rev. E Stat. Nonlin. Soft Matter Phys , vol.65 , pp. 026107
    • Holme, P.1    Kim, B.J.2
  • 18
    • 0141538180 scopus 로고    scopus 로고
    • Drug receptor/effector polymorphisms and pharmacogenetics: Current status and challenges
    • Johnson, J.A. and Lima, J.J. 2003. Drug receptor/effector polymorphisms and pharmacogenetics: Current status and challenges. Pharmacogenetics 13: 525-534.
    • (2003) Pharmacogenetics , vol.13 , pp. 525-534
    • Johnson, J.A.1    Lima, J.J.2
  • 19
    • 0038543016 scopus 로고    scopus 로고
    • Noh, J.D. 2003. Exact scaling properties of a hierarchical network model. Phys. Rev. E Stat. Nonlin. Soft Matter Phys. 67: 045103.doi: 10.1103/PhysRevE.67.045103.
    • Noh, J.D. 2003. Exact scaling properties of a hierarchical network model. Phys. Rev. E Stat. Nonlin. Soft Matter Phys. 67: 045103.doi: 10.1103/PhysRevE.67.045103.
  • 30
    • 0037267313 scopus 로고    scopus 로고
    • Knockouts model the 100 best-selling drugs - Will they model the next 100?
    • Zambrowicz, B.P. and Sands, A.T. 2003. Knockouts model the 100 best-selling drugs - Will they model the next 100? Nat. Rev. Drug Discov. 2: 38-51.
    • (2003) Nat. Rev. Drug Discov , vol.2 , pp. 38-51
    • Zambrowicz, B.P.1    Sands, A.T.2
  • 31
    • 33646532662 scopus 로고    scopus 로고
    • Progress and problems in the exploration of therapeutic targets
    • Zheng, C., Han, L., Yap, C.W., Xie, B., and Chen, Y. 2006. Progress and problems in the exploration of therapeutic targets. Drug Discov. Today 11: 412-420.
    • (2006) Drug Discov. Today , vol.11 , pp. 412-420
    • Zheng, C.1    Han, L.2    Yap, C.W.3    Xie, B.4    Chen, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.