Microarray analysis of Leflunomide-induced limb malformations in CD-1 mice

Reproductive Toxicology

Volumn 29, Issue 1, 2010, Pages 42-48

  Fukushima, Ryou ^a,b   Kaneto, Masako ^a   Kitagawa, Hiroshi ^b  

^a SHIONOGI AND CO LTD   (Japan)

^b KOBE UNIVERSITY   (Japan)

Author keywords

Dihydroorotate dehydrogenase; Leflunomide; Limb deformity; Microarray; Tyrosine kinase

Indexed keywords

CHOLESTEROL; DIHYDROOROTATE DEHYDROGENASE; LEFLUNOMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYOTOXICITY; ENZYME INHIBITION; FEMALE; GENE CONTROL; GENE EXPRESSION; LIMB MALFORMATION; MALE; MESENCHYME CELL; MICROARRAY ANALYSIS; MITOSIS INHIBITION; MORNING DOSAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; TERATOGENICITY;

ANIMALS; CELL DIVISION; CHOLESTEROL; ENZYME INHIBITORS; FEMALE; GESTATIONAL AGE; IMMUNOSUPPRESSIVE AGENTS; ISOXAZOLES; LIMB BUDS; LIMB DEFORMITIES, CONGENITAL; MESODERM; MICE; MICE, INBRED ICR; MITOTIC INDEX; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ANIMALIA; MUS;

EID: 73449125083     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2009.09.001     Document Type: Article

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