Transcriptional regulation of the AP-2α promoter by BTEB-1 and AP- 2rep, a novel wt-1/egr-related zinc finger repressor

Molecular and Cellular Biology

Volumn 19, Issue 1, 1999, Pages 194-204

  Imhof, Axel ^b   Schuierer, Marion ^d   Werner, Oliver ^d   Moser, Markus ^d   Roth, Christina ^d   Bauer, Reinhard ^c   Buettner, Reinhard ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; RNA; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; DNA SEQUENCE; FETUS; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

EID: 0032954201     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.19.1.194     Document Type: Article

References (28)

1. Baskin, F., Y. P. Li, L. B. Hersh, R. M. Davis, and R. N. Rosenberg. 1997. An AP-2 binding sequence within exon 1 of human and porcine choline acetyl-transferase genes enhances transcription in neural cells. Neuroscience 76: 821-827.
2. Bauer, R., A. Pscherer, A. Imhof, M. Moser, H. Kopp, S. Seegers, M. Kerscher, M. A. Tainsky, F. Hofstaedter, and R. Buettner. 1994. The genomic structure of the human AP-2 gene. Nucleic Acids Res. 22:1413-1420.
3. Bennett, A. M., T. L. Tang, S. Sugimoto, C. T. Walsh, and B. G. Neel. 1994. Protein tyrosine phosphatase SHPTP-2 couples platelet-derived growth factor receptor β to ras. Proc. Natl. Acad. Sci. USA 91:7335-7339.
4. Bosher, J. M., T. Williams, and H. C. Hurst. 1995. The developmentally regulated transcription factor AP-2 is involved in c-erbB2 overexpression in human mammary carcinoma. Proc. Natl. Acad. Sci. USA 92:744-747.
5. Buettner, R., P. Kannan, A. Imhof, R. Bauer, S. O. Yim, R. Glockshuber, M. W. VanDyke, and M. A. Tainsky. 1993. An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2. Mol. Cell. Biol. 13:4174-4185.
6. Byrne, C., M. A. Tainsky, and E. Fuchs. 1994. Programming gene expression in developing epidermis. Development 120:2369-2383.
7. Chazaud, C., M. Oulad-Abdelghani, P. Bouillet, D. Decimo, P. Chambon, and H. Dolle. 1996. AP-2.2, a novel gene related to AP-2, is expressed in the formbrain, limbs and face during mouse embryogenesis. Mech. Dev. 54:83-94.
8. Creaser, P. C., D. A. D'Argenio, and T. Williams. 1996. Comparative and functional analysis of the AP-2 promoter indicates that conserved octamer and initiator elements are critical for activity. Nucleic Acids Res. 13:2597-2605.
9. Gaubatz, S., A. Imhuf, R. Dosch, O. Werner, P. Milchell, R. Buettner, and M. Eilers. 1995. Transcription factor AP-2 negatively regulates gene activation by myc. EMBO J. 14:1508-1519.
10. Gille, J., R. A. Swerlick, and S. W. Caughman, 1997. Transforming growth factor-alpha-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation. EMBO J. 16:750-759.
11. Imataka, H., K. Sofawa, K. Yasumoto, Y. Kikuchi, K. Sasano, A. Kobayashi, M. Hayami, and Y. Fujii-Kuriyama. 1992. Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-450 1Al gene. EMBO J. 11:3663-3671.
12. Imataka, H., K. Nakayama, K. Yasumoto, A, Mizuno, Y. Fujii-Kuriyama, and M. Hayami. 1994. Cell-specific translational control of transcription factor BTEB expression. J. Biol. Chem. 269:20668-20673.
13. Kannan, P., R. Buettner, P. J. Chiao, S. O. Yim, M. Sarkiss, and M. A. Tainsky. 1994. N-ras oncogene causes AP-2 transcriptional self-interference, which leads to transformation. Genes Dev. 8:1258-1269.
14. Mitchell, P. J., P. M. Timmons, J. M. Hebert, P. W. Rigby, and R. Tjian. 1991. Transcription factor AP-2 is expressed in neural crest lineages during mouse embryogenesis. Genes Dev. 5:105-119.
15. Moser, M., A. Pscherer, A. Imhof, R. Bauer, M. Kerscher, W. Amselgruber, F. Sinowatz, F. Hofstaedter, R. Schüle, and R. Buettner. 1995. Molecular cloning and characterization of a second AP-2 transcription activator gene. AP-2β. Development 121:2779-2788.
16. Moser, M., J. Rüschof, and R. Buettner. 1997. Comparative analysis of AP-2a and AP-2β gene expression during murine embryogenesis. Dev. Dyn. 208:115-124.
17. Moser, M., A. Pscherer, C. Roth, J. Becker, G. Mücher, K. Zerres, C. Dixkens, J. Weis, L. Guay-Woodford, R. Buettner, and R. Fässler. 1997. Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2β. Genes Dev. 11:1938-1948.
18. Oulad-Abdelghani, M., P. Bouillet, C. Chazaud, P. Dollé, and P. Chambon. 1996. AP-2.2: a novel AP-2 related transcription factor induced by retinoic acid during differentiation of P19 embryonal carcinoma cells. Exp. Cell Res. 225:338-347.
19. Pscherer, A., U. Dörflinger, J. Kirfel, K. Gawlas, J. Rüschoff, R. Buettner, and R. Schüle. 1996. The helix-loop-helix transcription factor SEF-2 regulates the activity of a novel initiator element in the promoter of the human somatostating receptor II gene. EMBO J. 15:6680-6690.
20. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989 Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
21. Schorle. H., P. Meier, M. Buchert, R. Jaenisch, and P. J. Mitchell. 1996. Transcription factor AP-2 essential for cranial closure and craniofacial development. Nature 381:235-238.
22. Sepulveda, A. R., S. L. Huang, K. M. Lebovitz, and M. W. Lieberman. 1997. A 346-base pair region of the mouse gamma-glutamyl transpeplidase type II promoter contains sufficient cis-acting elements for kidney-restricted expression in transgenic mice. J. Biol. Chem. 272:11959-11967.
23. Sogawa, K., Y. Kikuchi, H. Imataka, and Y. Fujii-Kariyama. 1993. Comparison of DNA-binding properties between BTEB and SP-1. J. Biochem. 114: 605-609.
24. Wang, D., T. H. Shin, and J. E. Kudlow. 1997. Transcription factor AP-2 controls transcription of the human transforming growth factor-alpha gene. J. Biol. Chem. 272:14244-14250.
25. Williams, T., A. Admon, B. Lüschcr, and R. Tjian. 1988. Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements. Genes Dev. 2:1557-1569.
26. Williams, T., and R. Tjian. 1991 Analysis of the DNA-binding and activation properties of the human transcription factor AP-2. Genes Dev. 5:670-682.
27. Williams, T., and R. Tjian. 1991. Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins. Science 251: 1067-1071.
28. Zhang, J., S. Hagopian-Donaldson, G. Serbedzija, J. Elsemore, D. Plehn-Dujowich. A. P. McMahon, R. A. Flavell, and T. Williams. 1996. Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2. Nature 381:238-241.