Synthesis, molecular targets, and antitumor activities of substituted tetrahydro-1-oxopyrano[4,3-b][1]benzopyrans and nanogels for drug delivery

Anti-Cancer Agents in Medicinal Chemistry

Volumn 9, Issue 8, 2009, Pages 864-876

  Perchellet, Elisabeth M ^a   Perchellet, Jean Pierre H ^a   Ganta, Chanran K ^a   Troyer, Deryl L ^a   Shi, Aibin ^a   Hua, Duy H ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

1H,7H 5a,6,8,9 tetrahydro 1 oxopyrano 4,3 b 1 benzopyrans (tricyclic pyrones); 6 hydroxymethyl 1,4 anthracenedione (AQ10); Antitumor agents; DNA synthesis; Drug delivery; Mitotic index; Nucleoside transport; PEG PEI nanogel; Tubulin polymerization; Tumor cell growth

Indexed keywords

2 PYRIDYL BENZOPYRAN; 3 PYRIDYL BENZOPYRAN; 5A,6,8,9 TETRAHYDRO 1 OXOPYRANO[4,3 B][1]BENZOPYRAN DERIVATIVE; 6 HYDROXYMETHYL 1,4 ANTHRACENEDIONE; ANTINEOPLASTIC AGENT; BENZOPYRAN DERIVATIVE; COLCHICINE; DNA; DOXORUBICIN; MACROGOL; NANOPARTICLE; PACLITAXEL; POLYETHYLENEIMINE; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING SITE; CANCER CELL CULTURE; CELL PROLIFERATION; CHEMICAL REACTION; DNA SYNTHESIS; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HUMAN; IC 50; IN VITRO STUDY; LEWIS CARCINOMA; LUNG CARCINOMA; MICROTUBULE ASSEMBLY; MULTIDRUG RESISTANCE; NANOENCAPSULATION; NONHUMAN; OVARY CARCINOMA; SOLID TUMOR; STEREOCHEMISTRY;

ANTINEOPLASTIC AGENTS; BENZOPYRANS; DRUG CARRIERS; DRUG SCREENING ASSAYS, ANTITUMOR; NANOSTRUCTURES;

EID: 73449099586     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152009789124682     Document Type: Article

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