Syntheses and bioactivities of tricyclic pyrones

Tetrahedron

Volumn 59, Issue 26, 2003, Pages 4795-4803

  Hua, Duy H ^a   Huang, Xiaodong ^a   Tamura, Masafumi ^a   Chen, Yi ^a   Woltkamp, Melissa ^a   Jin, Lee Way ^b   Perchellet, Elisabeth M ^a   Perchellet, Jean Pierre ^a   Chiang, Peter K ^c   Namatame, Ichiji ^d   Tomoda, Hiroshi ^d  

^a KANSAS STATE UNIVERSITY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^d KITASATO UNIVERSITY   (Japan)

Author keywords

ACAT inhibitors; Alzheimer's disease; Amyloid peptides; APP C99 induced cell death; CETP inhibitors; Tricyclic pyrones

Indexed keywords

(7 ISOPROPENYL 1H,7H 5A,6,8,9 TETRAHYDRO 1 OXOPYRANO[4,3 B][1]BENZOPYRAN 3 YL)ACETIC ACID; 3 METHYL 7 [2 (METHANE SULFONYLOXY) 1 METHYLETHYL] 1H,7H 5A,6,8,9 TETRAHYDRO 1 OXOPYRANO[4,3 B][1]BENZOPYRAN; 3 [(7 ISOPROPENYL 1H,7H 5A,6,8,9 TETRAHYDRO 1 OXOPYRAN[4,3 B][1]BENZOPYRAN 3 YL)METHYLCARBAMOYL] 4 OXO 4 (4 NITROPHENYLAMINO)BUTANOIC ACID; 6 CHLOROPURINE; 7 ISOPROPENYL 3 METHYL 1H,7H 5A,6,8,9 TETRAHYDRO 1 OXOPYRANO[4,3 B][1]BENZOPYRAN; 7 [2 (N 10 ADENYL) 1 METHYLETHYL] 3 METHYL 1H,7H 5A,6,8,9 TETRAHYDRO 1 OXOPYRANO[4,3 B][1]BENZOPYRAN; 7 [2 (N 3 ADENYL) 1 METHYLETHYL] 3 METHYL 1H,7H 5A,6,8,9 TETRAHYDRO 1 OXOPYRANO[4,3 B][1]BENZOPYRAN; 7 [2 (N 9 ADENYL) 1 METHYLETHYL] 3 METHYL 1H,7H 5A,6,8,9 TETRAHYDRO 1 OXOPYRANO[4,3 B][1]BENZOPYRAN; ACETIC ACID DERIVATIVE; ADENINE DERIVATIVE; AMIDE; AMINE; AMYLOID BETA PROTEIN; ASPARTIC ACID; BENZYL(7 ISOPROPENYL 1H,7H 5A,6,8,9 TETRAHYDRO 1 OXOPYRANO[4,3 B]BENZOPYRAN 3 YL)ACETATE; BENZYL[10 HYDROXY 7 (2 HYDROXY 1 METHYLETHYL) 1H,7H 5A,6,8,9 TETRAHYDRO 1 OXOPYRANO[4,3,B][1]BENZOPYRAN 3 YL]ACETATE; BENZYL[7 (2 HYDROXY 1 METHYLMETHYLETHYL) 1H,7H 5A,6,8,9 TETRAHYDRO 1 OXOPYRANO[4,3 B][1]BENZOPYRAN 3 YL]ACETATE; CARBON DIOXIDE; CARBOXYLIC ACID; CHEMICAL COMPOUND; ESTER; LEAD; MESYLIC ACID; METHYL GROUP; PEPTIDE DERIVATIVE; PROPANE; PROTEIN PRECURSOR; PURINE DERIVATIVE; PYRAN DERIVATIVE; PYRONE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CARBOXY TERMINAL SEQUENCE; CARBOXYLATION; CHEMICAL MODIFICATION; DRUG ACTIVITY; EVALUATION; GAS CHROMATOGRAPHY; ISOMER; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NERVE CELL NECROSIS; NEUROPROTECTION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; TOXICITY;

EID: 0037838746     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(03)00687-2     Document Type: Article

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