Antitumor activity of tricyclic pyrone analogs, a new synthetic class of microtubule de-stabilizing agents, in the murine EMT-6 mammary tumor cell line in vitro

Anti-Cancer Drugs

Volumn 9, Issue 6, 1998, Pages 565-576

  Perchellet, Elisabeth M ^a   Ladesich, James B ^a   Chen, Yi ^b   Sin, Hong Sig ^b   Hua, Duy H ^b   Kraft, Susan L ^c   Perchellet, Jean Pierre ^a  

^a Div of Biology   (United States)

^b Department of Chemistry ^*  (United States)

^c KANSAS STATE UNIVERSITY   (United States)

Author keywords

DNA synthesis; Mammary sarcoma; Mitotic index; Tricyclic pyrones; Tubulin polymerization; Tumor cell growth

Indexed keywords

H 10; H 14; H 16; PYRONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE; DNA SYNTHESIS; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; MICROTUBULE ASSEMBLY; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TUMOR CELL LINE; TUMOR GROWTH;

EID: 0031846864     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199807000-00008     Document Type: Article

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